Results 241 to 250 of about 853,838 (334)

SnapShot: Small RNA-Mediated Epigenetic Modifications

, 2007
Yanxia Bei, Sigal Pressman, Richard W. Carthew   +2 more
openalex   +1 more source

Correction: Nucleotide modifications in messenger RNA and their role in development and disease [PDF]

, 2019
Veronica Dezi, Chavdar Ivanov, Irmgard U. Haussmann, Matthias Soller   +3 more
openalex   +1 more source

ModiDeC: a multi-RNA modification classifier for direct nanopore sequencing. [PDF]

Nucleic Acids Res
Alagna N, Mündnich S, Miedema J, Pastore S, Lehmann L, Wierczeiko A, Friedrich J, Walz L, Jörg M, Butto T, Friedland K, Helm M, Gerber S.   +12 more
europepmc   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

Epitranscriptomic RNA m⁶A Modification in Cancer Therapy Resistance: Challenges and Unrealized Opportunities [PDF]

Mohammad B. Uddin, Zhishan Wang, Chengfeng Yang   +2 more
openalex   +1 more source

Beyond RNA modification: a novel role for tRNA modifying enzyme in oxidative stress response and metabolism. [PDF]

Nucleic Acids Res
Fruchard L, Sudol C, Rouard C, Treffkorn-Maurau A, Hardy L, Bos J, Duchateau M, Giai Gianetto Q, Matondo M, Bonhomme F, Thuillier Q, Marchand V, Motorin Y, Bregeon D, Mazel D, Hamdane D, Baharoglu Z.   +16 more
europepmc   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

Structure of tRNA Dimethylallyltransferase: RNA Modification through a Channel

, 2007
Wei Xie, Chun Zhou, Raven H. Huang
openalex   +1 more source