Results 261 to 270 of about 564,596 (305)

Beyond RNA modification: a novel role for tRNA modifying enzyme in oxidative stress response and metabolism. [PDF]

Nucleic Acids Res
Fruchard L, Sudol C, Rouard C, Treffkorn-Maurau A, Hardy L, Bos J, Duchateau M, Giai Gianetto Q, Matondo M, Bonhomme F, Thuillier Q, Marchand V, Motorin Y, Bregeon D, Mazel D, Hamdane D, Baharoglu Z.   +16 more
europepmc   +1 more source

Unraveling the Clinical Landscape of RNA Modification Regulators with Multi-Omics Insights in Pan-Cancer. [PDF]

Cancers (Basel)
Li Q, Zhang J, Cao Z, Wang J, Song J, Yi X.   +5 more
europepmc   +1 more source

Research on RNA modification in disease diagnosis and prognostic biomarkers: current status and challenges. [PDF]

Brief Bioinform
Shi H, Li Z, Zou Q, Yang H.
europepmc   +1 more source

An Expanded View of RNA Modification with Carbohydrate-Based Metabolic Probes. [PDF]

JACS Au
Hazemi ME, Geeson MB, Müller FM, Mikutis S, Enright AJ, Bernardes GJL.   +5 more
europepmc   +1 more source

Systematic benchmarking of basecalling models for RNA modification detection with highly-multiplexed nanopore sequencing

Diensthuber G, Milenkovic I, Llovera L, Milovanovic A, Pelizzari F, Novoa EM.   +5 more
europepmc   +1 more source

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RNA modifications in cancer

British Journal of Cancer, 2023
Currently, more than 170 modifications have been identified on RNA. Among these RNA modifications, various methylations account for two-thirds of total cases and exist on almost all RNAs. Roles of RNA modifications in cancer are garnering increasing interest. The research on m6A RNA methylation in cancer is in full swing at present.
Qiling Tang, Lvyuan Li, Yumin Wang, Pan Wu, Xiangchan Hou, Jiawei Ouyang, Chunmei Fan, Zheng Li, Fuyan Wang, Can Guo, Ming Zhou, Qianjin Liao, Hui Wang, Bo Xiang, Weihong Jiang, Guiyuan Li, Zhaoyang Zeng, Wei Xiong   +17 more
openaire   +2 more sources

RNA Modification in the Immune System

Annual Review of Immunology, 2023
Characterization of RNA modifications has identified their distribution features and molecular functions. Dynamic changes in RNA modification on various forms of RNA are essential for the development and function of the immune system. In this review, we discuss the value of innovative RNA modification profiling technologies to uncover the function of ...
Dali Han, Meng Michelle Xu
exaly   +3 more sources

RNA modifications in hematological malignancies

International Journal of Hematology, 2023
RNA modifications play an important role in various cancers including blood cancers by controlling gene expression programs critical for survival, proliferation and differentiation of cancer cells. While hundreds of RNA modifications have been identified, many have not been functionally characterized.
Zhen Jin, Kyle MacPherson, Zongmin Liu, Ly P. Vu   +3 more
openaire   +2 more sources

Role of RNA modifications in cancer

Nature Reviews Cancer, 2020
Specific chemical modifications of biological molecules are an efficient way of regulating molecular function, and a plethora of downstream signalling pathways are influenced by the modification of DNA and proteins. Many of the enzymes responsible for regulating protein and DNA modifications are targets of current cancer therapies.
Isaia Barbieri, Tony Kouzarides, Kouzarides Tony   +2 more
exaly   +3 more sources

Heterogeneity of chemical modifications on RNA

Biophysical Reviews, 2023
The chemical modifications of RNAs broadly impact almost all cellular events and influence various diseases. The rapid advance of sequencing and other technologies opened the door to global methods for profiling all RNA modifications, namely the "epitranscriptome." The mapping of epitranscriptomes in different cells and tissues unveiled that RNA ...
W. S. Sho Goh, Yi Kuang
openaire   +3 more sources