Results 251 to 260 of about 855,003 (301)

Immune‐Driven Expression in Inclusion Body Myositis With T‐Cell Large Granular Lymphocytic Leukemia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives T‐cell large granular lymphocytic leukemia (T‐LGLL), reported in up to 58% of inclusion body myositis (IBM) patients, is a rare leukemia of cytotoxic or less commonly helper T cells. The range of myopathies in T‐LGLL and the impact of coexisting T‐LGLL in IBM are not well understood. Our objectives are to investigate the spectrum of
Pannathat Soontrapa, Iago Pinal‐Fernandez, Pritikanta Paul, Michael P. Skolka, Margherita Milone, Min Shi, Mithun V. Shah, Maria Casal‐Dominguez, Katherine Pak, Andrew L. Mammen, Teerin Liewluck   +10 more
wiley   +1 more source

Biological interpretation of DNA/RNA modification by ALKBH proteins and their role in human cancer. [PDF]

Eur J Med Res
Yang S, Xing J, Song Y, Cui J, Bao L, Xi Q, Zuo Y.   +6 more
europepmc   +1 more source

Role of N6-methyladenosine RNA modification in cancer. [PDF]

MedComm (2020)
Qu Y, Gao N, Zhang S, Gao L, He B, Wang C, Gong C, Shi Q, Li Z, Yang S, Xiao Y.   +10 more
europepmc   +1 more source

A comparative evaluation of computational models for RNA modification detection using nanopore sequencing with RNA004 chemistry. [PDF]

Brief Bioinform
Zou Y, Ahsan MU, Chan J, Meng W, Gao SJ, Huang Y, Wang K.   +6 more
europepmc   +1 more source

Letter to the editor regarding "Inhibition of Mettl3-mediated m6A RNA modification of HMGCS1 protects retinal ganglion cells from glutamate excitotoxicity-induced ferroptosis in a rat model of glaucoma." [PDF]

Int J Surg
Ye L, Hu X.
europepmc   +1 more source

Huashi Runzao decoction for primary Sjögren disease: a double-blind, randomized controlled trial combined with m6A and m5C RNA modification analysis. [PDF]

Front Pharmacol
Huang Z, Deng T, Zhang X, Lei C, Zhang Y, Yang J, He Q, Liao J, Chen J, Yang L, Gu X, Luo J, Xiao C, Tao Q.   +13 more
europepmc   +1 more source

Systematic benchmarking of basecalling models for RNA modification detection with highly-multiplexed nanopore sequencing

Diensthuber G, Milenkovic I, Llovera L, Milovanovic A, Pelizzari F, Novoa EM.   +5 more
europepmc   +1 more source

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RNA modifications in cancer

British Journal of Cancer, 2023
Currently, more than 170 modifications have been identified on RNA. Among these RNA modifications, various methylations account for two-thirds of total cases and exist on almost all RNAs. Roles of RNA modifications in cancer are garnering increasing interest. The research on m6A RNA methylation in cancer is in full swing at present.
Qiling Tang, Lvyuan Li, Yumin Wang, Pan Wu, Xiangchan Hou, Jiawei Ouyang, Chunmei Fan, Zheng Li, Fuyan Wang, Can Guo, Ming Zhou, Qianjin Liao, Hui Wang, Bo Xiang, Weihong Jiang, Guiyuan Li, Zhaoyang Zeng, Wei Xiong   +17 more
openaire   +2 more sources

Transfer RNA Modification

EcoSal Plus, 2005
Transfer RNA (tRNA) from all organisms on this planet contains modified nucleosides, which are derivatives of the four major nucleosides. tRNA from Escherichia coli/Salmonella enterica contains 31 different modified nucleosides, which are all, except for one (Queuosine[Q]), synthesized on an oligonucleotide ...
Glenn R, Björk, Tord G, Hagervall
openaire   +2 more sources

RNA modifications in hematological malignancies

International Journal of Hematology, 2023
RNA modifications play an important role in various cancers including blood cancers by controlling gene expression programs critical for survival, proliferation and differentiation of cancer cells. While hundreds of RNA modifications have been identified, many have not been functionally characterized.
Zhen Jin, Kyle MacPherson, Zongmin Liu, Ly P. Vu   +3 more
openaire   +2 more sources