Human Retrovirus Genomic RNA Packaging [PDF]
Viruses, 2022 Two non-covalently linked copies of the retrovirus genome are specifically recruited to the site of virus particle assembly and packaged into released particles.
Heather M. Hanson +3 more
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The impact of local assembly rules on RNA packaging in a T = 1 satellite plant virus. [PDF]
PLoS Computational Biology, 2021 The vast majority of viruses consist of a nucleic acid surrounded by a protective icosahedral protein shell called the capsid. During viral infection of a host cell, the timing and efficiency of the assembly process is important for ensuring the ...
Sam R Hill +2 more
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RNA Origami: Packaging a Segmented Genome in Orbivirus Assembly and Replication [PDF]
Viruses, 2021 Understanding how viruses with multi-segmented genomes incorporate one copy of each segment into their capsids remains an intriguing question. Here, we review our recent progress and describe the advancements made in understanding the genome packaging ...
Po-Yu Sung, Polly Roy
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The curious case of genome packaging and assembly in RNA viruses infecting plants [PDF]
Frontiers in Genetics, 2023 Genome packaging is the crucial step for maturation of plant viruses containing an RNA genome. Viruses exhibit a remarkable degree of packaging specificity, despite the probability of co-packaging cellular RNAs.
Tushar Ranjan +9 more
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Dimerisation of HIV-2 genomic RNA is linked to efficient RNA packaging, normal particle maturation and viral infectivity [PDF]
Retrovirology, 2007 Background Retroviruses selectively encapsidate two copies of their genomic RNA, the Gag protein binding a specific RNA motif in the 5' UTR of the genome. In human immunodeficiency virus type 2 (HIV-2), the principal packaging signal (Psi) is upstream of
Crowther R Anthony +3 more
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From Cells to Virus Particles: Quantitative Methods to Monitor RNA Packaging [PDF]
Viruses, 2016 In cells, positive strand RNA viruses, such as Retroviridae, must selectively recognize their full-length RNA genome among abundant cellular RNAs to assemble and release particles.
Mireia Ferrer +4 more
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MoMuLV and HIV-1 nucleocapsid proteins have a common role in genomic RNA packaging but different in late reverse transcription. [PDF]
PLoS ONE, 2012 Retroviral nucleocapsid proteins harbor nucleic acid chaperoning activities that mostly rely on the N-terminal basic residues and the CCHC zinc finger motif.
Célia Chamontin +4 more
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Kinetic Studies on the Interaction of HIV-1 Gag Protein with the HIV-1 RNA Packaging Signal [PDF]
VirusesDuring HIV-1 virus assembly, the genomic RNA (vRNA) is selected for packaging by the viral protein Gag because it contains a specific packaging signal, Psi. While there have been numerous studies of Gag–Psi interactions, there is almost no information on
Constance Rink +3 more
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Nucleocapsid protein-dependent assembly of the RNA packaging signal of Middle East respiratory syndrome coronavirus [PDF]
Journal of Biomedical Science, 2018 Background Middle East respiratory syndrome coronavirus (MERS-CoV) consists of a positive-sense, single-stranded RNA genome and four structural proteins: the spike, envelope, membrane, and nucleocapsid protein. The assembly of the viral genome into virus
Wei-Chen Hsin +6 more
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Elements in the 5′ Untranslated Region of Viral RNA Important for HIV Gag Recognition and Cross-Packaging [PDF]
VirusesDuring retrovirus assembly, Gag packages unspliced viral RNA as the virion genome. Genome packaging is usually specific with occasional exceptions of cross-packaging RNA from distantly related retroviruses.
Zetao Cheng +5 more
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