Human Retrovirus Genomic RNA Packaging [PDF]
Viruses, 2022 Two non-covalently linked copies of the retrovirus genome are specifically recruited to the site of virus particle assembly and packaged into released particles.
Heather M. Hanson +3 more
doaj +4 more sources
RNA Structures and Their Role in Selective Genome Packaging [PDF]
Viruses, 2021 To generate infectious viral particles, viruses must specifically select their genomic RNA from milieu that contains a complex mixture of cellular or non-genomic viral RNAs.
Liqing Ye +2 more
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From Cells to Virus Particles: Quantitative Methods to Monitor RNA Packaging [PDF]
Viruses, 2016 In cells, positive strand RNA viruses, such as Retroviridae, must selectively recognize their full-length RNA genome among abundant cellular RNAs to assemble and release particles.
Simon Henriet +2 more
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RNA Encapsidation and Packaging in the Phleboviruses [PDF]
Viruses, 2016 The Bunyaviridae represents the largest family of segmented RNA viruses, which infect a staggering diversity of plants, animals, and insects. Within the family Bunyaviridae, the Phlebovirus genus includes several important human and animal pathogens ...
Jean-Marc Lanchy, J Stephen Lodmell
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Coronavirus genomic RNA packaging [PDF]
Virology, 2019 RNA viruses carry out selective packaging of their genomes in a variety of ways, many involving a genomic packaging signal. The first coronavirus packaging signal was discovered nearly thirty years ago, but how it functions remains incompletely understood.
Paul S Masters
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The impact of local assembly rules on RNA packaging in a T = 1 satellite plant virus. [PDF]
PLoS Computational Biology, 2021 The vast majority of viruses consist of a nucleic acid surrounded by a protective icosahedral protein shell called the capsid. During viral infection of a host cell, the timing and efficiency of the assembly process is important for ensuring the ...
Sam R Hill +2 more
doaj +2 more sources
Packaging of Genomic RNA in Positive-Sense Single-Stranded RNA Viruses: A Complex Story
Viruses, 2019 The packaging of genomic RNA in positive-sense single-stranded RNA viruses is a key part of the viral infectious cycle, yet this step is not fully understood. Unlike double-stranded DNA and RNA viruses, this process is coupled with nucleocapsid assembly.
Mauricio Comas-García
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RNA Origami: Packaging a Segmented Genome in Orbivirus Assembly and Replication
Viruses, 2021 Understanding how viruses with multi-segmented genomes incorporate one copy of each segment into their capsids remains an intriguing question. Here, we review our recent progress and describe the advancements made in understanding the genome packaging ...
Po-Yu Sung, Polly Roy, Roy Polly
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Kinetic Studies on the Interaction of HIV-1 Gag Protein with the HIV-1 RNA Packaging Signal [PDF]
VirusesDuring HIV-1 virus assembly, the genomic RNA (vRNA) is selected for packaging by the viral protein Gag because it contains a specific packaging signal, Psi. While there have been numerous studies of Gag–Psi interactions, there is almost no information on
Constance Rink +3 more
doaj +2 more sources
Nucleocapsid protein-dependent assembly of the RNA packaging signal of Middle East respiratory syndrome coronavirus [PDF]
Journal of Biomedical Science, 2018 Background Middle East respiratory syndrome coronavirus (MERS-CoV) consists of a positive-sense, single-stranded RNA genome and four structural proteins: the spike, envelope, membrane, and nucleocapsid protein. The assembly of the viral genome into virus
Wei-Chen Hsin +6 more
doaj +2 more sources