Results 11 to 20 of about 113,079 (105)

Identification of the Initial Nucleocapsid Recognition Element in the HIV-1 RNA Packaging Signal [PDF]

Proceedings of the National Academy of Sciences of the United States of America, 2020
Siarhei Kharytonchyk, Alice Telesnitsky, Alexis Waller   +2 more
exaly   +2 more sources

Coronavirus Genomic RNA Packaging [PDF]

Virology, 2019
Paul S Masters
exaly   +2 more sources

The curious case of genome packaging and assembly in RNA viruses infecting plants

Frontiers in Genetics, 2023
Genome packaging is the crucial step for maturation of plant viruses containing an RNA genome. Viruses exhibit a remarkable degree of packaging specificity, despite the probability of co-packaging cellular RNAs.
Tushar Ranjan, Ravi Ranjan Kumar, Mohammad Ansar, Jitesh Kumar, Auroshikha Mohanty, Anamika Kumari, Khushbu Jain, Kumari Rajani, Sailabala Dei, Mohammad Feza Ahmad   +9 more
doaj   +1 more source

Plasma Membrane Anchoring and Gag:Gag Multimerization on Viral RNA Are Critical Properties of HIV-1 Gag Required To Mediate Efficient Genome Packaging

mBio, 2021
Human immunodeficiency virus type 1 (HIV-1) Gag selects and packages the HIV RNA genome during virus assembly. However, HIV-1 RNA constitutes only a small fraction of the cellular RNA.
Alice Duchon, Steven Santos, Jianbo Chen, Matthew Brown, Olga A. Nikolaitchik, Sheldon Tai, Jeffrey A. Chao, Eric O. Freed, Vinay K. Pathak, Wei-Shau Hu   +9 more
doaj   +1 more source

Influence of Gag and RRE Sequences on HIV-1 RNA Packaging Signal Structure and Function [PDF]

Journal of Molecular Biology, 2018
Siarhei Kharytonchyk, Alice Telesnitsky, Aishwarya S Iyer   +2 more
exaly   +2 more sources

HIV-1 Packaging Visualised by In-Gel SHAPE

Viruses, 2021
HIV-1 packages two copies of its gRNA into virions via an interaction with the viral structural protein Gag. Both copies and their native RNA structure are essential for virion infectivity.
Aaron R. D’Souza, Dhivya Jayaraman, Ziqi Long, Jingwei Zeng, Liam J. Prestwood, Charlene Chan, Dennis Kappei, Andrew M. L. Lever, Julia C. Kenyon   +8 more
doaj   +1 more source

Disruption of Specific RNA-RNA Interactions in a Double-Stranded RNA Virus Inhibits Genome Packaging and Virus Infectivity. [PDF]

PLoS Pathogens, 2015
Bluetongue virus (BTV) causes hemorrhagic disease in economically important livestock. The BTV genome is organized into ten discrete double-stranded RNA molecules (S1-S10) which have been suggested to follow a sequential packaging pathway from smallest ...
Teodoro Fajardo, Po-Yu Sung, Polly Roy
doaj   +1 more source

Reovirus Low-Density Particles Package Cellular RNA

Viruses, 2021
Packaging of segmented, double-stranded RNA viral genomes requires coordination of viral proteins and RNA segments. For mammalian orthoreovirus (reovirus), evidence suggests either all ten or zero viral RNA segments are simultaneously packaged in a ...
Timothy W. Thoner, Xiang Ye, John Karijolich, Kristen M. Ogden   +3 more
doaj   +1 more source

Packaging signal of influenza A virus

Virology Journal, 2021
Influenza A virus (IAV) contains a genome with eight single-stranded, negative-sense RNA segments that encode 17 proteins. During its assembly, all eight separate viral RNA (vRNA) segments are incorporated into virions in a selective manner.
Xiuli Li, Min Gu, Qinmei Zheng, Ruyi Gao, Xiufan Liu   +4 more
doaj   +1 more source

RNA Origami: Packaging a Segmented Genome in Orbivirus Assembly and Replication

Viruses, 2021
Understanding how viruses with multi-segmented genomes incorporate one copy of each segment into their capsids remains an intriguing question. Here, we review our recent progress and describe the advancements made in understanding the genome packaging ...
Po-Yu Sung, Polly Roy
doaj   +1 more source