Results 31 to 40 of about 113,079 (105)
In vivo studies of genomic packaging in the dsRNA bacteriophage Φ8
BMC Microbiology, 2005 Background Φ8 is a bacteriophage containing a genome of three segments of double-stranded RNA inside a polyhedral capsid enveloped in a lipid-containing membrane. Plus strand RNA binds and is packaged by empty procapsids.
Mindich Leonard, Qiao Xueying, Qiao Jian
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HIV-1 RNA genome packaging: it’s G-rated
mBioA member of the Retroviridae, human immunodeficiency virus type 1 (HIV-1), uses the RNA genome packaged into nascent virions to transfer genetic information to its progeny.
Alice Duchon, Wei-Shau Hu
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VirusesDuring retrovirus assembly, Gag packages unspliced viral RNA as the virion genome. Genome packaging is usually specific with occasional exceptions of cross-packaging RNA from distantly related retroviruses.
Zetao Cheng +5 more
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Role of genome topology in the stability of viral capsids
Physical Review Research, 2023 We explore how the stability of RNA viruses depends on genome topology and interactions between RNA and the capsid proteins. RNA is modeled as a branched polymer with 12 attractive sites (packaging signals) that can form bonds with 12 icosahedrally ...
James Daniel Farrell +2 more
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Trans-Acting RNA–RNA Interactions in Segmented RNA Viruses
Viruses, 2019 RNA viruses represent a large and important group of pathogens that infect a broad range of hosts. Segmented RNA viruses are a subclass of this group that encode their genomes in two or more molecules and package all of their RNA segments in a single ...
Laura R. Newburn, K. Andrew White
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RNA Encapsidation and Packaging in the Phleboviruses
Viruses, 2016 The Bunyaviridae represents the largest family of segmented RNA viruses, which infect a staggering diversity of plants, animals, and insects. Within the family Bunyaviridae, the Phlebovirus genus includes several important human and animal pathogens ...
Katherine E. Hornak +2 more
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Sequences within both the 5' UTR and Gag are required for optimal in vivo packaging and propagation of mouse mammary tumor virus (MMTV) genomic RNA. [PDF]
PLoS ONE, 2012 BACKGROUND: This study mapped regions of genomic RNA (gRNA) important for packaging and propagation of mouse mammary tumor virus (MMTV). MMTV is a type B betaretrovirus which preassembles intracellularly, a phenomenon distinct from retroviruses that ...
Farah Mustafa +7 more
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A conserved influenza A virus nucleoprotein code controls specific viral genome packaging
Nature Communications, 2016 The nucleotide sequence of the eight genomic RNA segments of influenza A virus provides essential packaging signals, but how these sequences are recognized is unknown. Here, Moreira et al.
Étori Aguiar Moreira +10 more
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Structure-Function Model for Kissing Loop Interactions That Initiate Dimerization of Ty1 RNA
Viruses, 2017 The genomic RNA of the retrotransposon Ty1 is packaged as a dimer into virus-like particles. The 5′ terminus of Ty1 RNA harbors cis-acting sequences required for translation initiation, packaging and initiation of reverse transcription (TIPIRT).
Eric R. Gamache +6 more
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Nature Communications, 2018 Influenza A virus packaging depends on interactions between nucleoprotein (NP) and viral RNA (vRNA), but the pattern of NP binding is unclear. Using PAR-CLIP, Williams et al.
Graham D. Williams +6 more
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