Results 51 to 60 of about 107,453 (245)

RNAglib: a python package for RNA 2.5 D graphs [PDF]

open access: yesBioinformatics, 2021
AbstractSummaryRNA 3D architectures are stabilized by sophisticated networks of (non-canonical) base pair interactions, which can be conveniently encoded as multi-relational graphs and efficiently exploited by graph theoretical approaches and recent progresses in machine learning techniques.
Vincent Mallet   +4 more
openaire   +3 more sources

Mechanism of RNA Packaging Motor

open access: yes, 2011
P4 proteins are hexameric RNA packaging ATPases of dsRNA bacteriophages of the Cystoviridae family. P4 hexamers are integral part of the inner polymerase core and play several essential roles in the virus replication cycle. P4 proteins are structurally related to the hexameric helicases and translocases of superfamily 4 (SF4) and other RecA-like ...
Mancini, E, Tuma, R
openaire   +3 more sources

Dimerisation of HIV-2 genomic RNA is linked to efficient RNA packaging, normal particle maturation and viral infectivity

open access: yesRetrovirology, 2007
Background Retroviruses selectively encapsidate two copies of their genomic RNA, the Gag protein binding a specific RNA motif in the 5' UTR of the genome. In human immunodeficiency virus type 2 (HIV-2), the principal packaging signal (Psi) is upstream of
Crowther R Anthony   +3 more
doaj   +1 more source

Characterization of Coronavirus DI RNA Packaging [PDF]

open access: yes, 1998
Studies of defective interfering (DI) RNAs of mouse hepatitis virus (MHV), suggest that a 69 nt-long packaging signal, which is located about 20 kb from the 5'-end of the 31 kb-long MHV genomic RNA, is necessary and sufficient for MHV genomic RNA packaging into MHV particles.
K H, Kim, K, Narayanan, S, Makino
openaire   +2 more sources

MoMuLV and HIV-1 nucleocapsid proteins have a common role in genomic RNA packaging but different in late reverse transcription. [PDF]

open access: yesPLoS ONE, 2012
Retroviral nucleocapsid proteins harbor nucleic acid chaperoning activities that mostly rely on the N-terminal basic residues and the CCHC zinc finger motif.
Célia Chamontin   +4 more
doaj   +1 more source

Modular assembly of chimeric phi29 packaging RNAs that support DNA packaging [PDF]

open access: yesBiochemical and Biophysical Research Communications, 2008
The bacteriophage phi29 DNA packaging motor is a protein/RNA complex that can produce strong force to condense the linear-double-stranded DNA genome into a pre-formed protein capsid. The RNA component, called the packaging RNA (pRNA), utilizes magnesium-dependent inter-molecular base-pairing interactions to form ring-shaped complexes.
Yun, Fang   +4 more
openaire   +2 more sources

Packaging of Non-Coding RNAs into Herpesvirus Virions: Comparisons to Coding RNAs [PDF]

open access: yesFrontiers in Genetics, 2011
The herpesviruses are a family of large DNA viruses capable of establishing lifelong infections. Recent reports have shown that herpesviruses package non-coding RNA into virions; this follows earlier observations showing that coding RNAs are detected in virions.
Melanie Ann Amen   +4 more
openaire   +3 more sources

Dimeric RNA recognition regulates HIV-1 genome packaging.

open access: yesPLoS Pathogens, 2013
How retroviruses regulate the amount of RNA genome packaged into each virion has remained a long-standing question. Our previous study showed that most HIV-1 particles contain two copies of viral RNA, indicating that the number of genomes packaged is ...
Olga A Nikolaitchik   +9 more
doaj   +1 more source

Analysis of efficiently packaged defective interfering RNAs of murine coronavirus: localization of a possible RNA-packaging signal [PDF]

open access: yesJournal of Virology, 1990
We have previously shown that most of the defective interfering (DI) RNA of mouse hepatitis virus (MHV) are not packaged into virions. We have now identified, after 21 serial undiluted passages of MHV, a small DI RNA, DIssF, which is efficiently packaged into virions.
S, Makino, K, Yokomori, M M, Lai
openaire   +2 more sources

In vivo studies of genomic packaging in the dsRNA bacteriophage Φ8

open access: yesBMC Microbiology, 2005
Background Φ8 is a bacteriophage containing a genome of three segments of double-stranded RNA inside a polyhedral capsid enveloped in a lipid-containing membrane. Plus strand RNA binds and is packaged by empty procapsids.
Mindich Leonard, Qiao Xueying, Qiao Jian
doaj   +1 more source

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