Results 11 to 20 of about 174,288 (316)

Reovirus Low-Density Particles Package Cellular RNA [PDF]

Viruses, 2021
Packaging of segmented, double-stranded RNA viral genomes requires coordination of viral proteins and RNA segments. For mammalian orthoreovirus (reovirus), evidence suggests either all ten or zero viral RNA segments are simultaneously packaged in a ...
Timothy W. Thoner, Xiang Ye, John Karijolich, Kristen M. Ogden   +3 more
doaj   +3 more sources

RNA Encapsidation and Packaging in the Phleboviruses [PDF]

Viruses, 2016
The Bunyaviridae represents the largest family of segmented RNA viruses, which infect a staggering diversity of plants, animals, and insects. Within the family Bunyaviridae, the Phlebovirus genus includes several important human and animal pathogens ...
Katherine E. Hornak, Jean-Marc Lanchy, J. Stephen Lodmell   +2 more
doaj   +3 more sources

Dimeric RNA recognition regulates HIV-1 genome packaging.

PLoS Pathogens, 2013
How retroviruses regulate the amount of RNA genome packaged into each virion has remained a long-standing question. Our previous study showed that most HIV-1 particles contain two copies of viral RNA, indicating that the number of genomes packaged is ...
Olga A Nikolaitchik, Kari A Dilley, William Fu, Robert J Gorelick, S-H Sheldon Tai, Ferri Soheilian, Roger G Ptak, Kunio Nagashima, Vinay K Pathak, Wei-Shau Hu   +9 more
doaj   +3 more sources

Reconstitution of the SARS-CoV-2 ribonucleosome provides insights into genomic RNA packaging and regulation by phosphorylation. [PDF]

J Biol Chem, 2022
Carlson CR, Adly AN, Bi M, Howard CJ, Frost A, Cheng Y, Morgan DO.   +6 more
europepmc   +3 more sources

HIV-1 RNA genome packaging: it’s G-rated

mBio
A member of the Retroviridae, human immunodeficiency virus type 1 (HIV-1), uses the RNA genome packaged into nascent virions to transfer genetic information to its progeny.
Alice Duchon, Wei-Shau Hu
doaj   +3 more sources

MMTV RNA packaging requires an extended long-range interaction for productive Gag binding to packaging signals. [PDF]

PLoS Biol
Prabhu SG, Pillai VN, Ali LM, Vivet-Boudou V, Chameettachal A, Bernacchi S, Mustafa F, Marquet R, Rizvi TA.   +8 more
europepmc   +2 more sources

Coordination of Genomic RNA Packaging with Viral Assembly in HIV-1. [PDF]

Viruses, 2016
Hellmund C, Lever AM.
europepmc   +3 more sources

The heart of the HIV RNA packaging signal? [PDF]

Proc Natl Acad Sci U S A, 2020
Rein A.
europepmc   +3 more sources

Dynamic interactions of retroviral Gag condensates with nascent viral RNA at transcriptional burst sites: implications for genomic RNA packaging. [PDF]

mBio
Kaddis Maldonado RJ, Parent LJ.
europepmc   +2 more sources

RNA Packaging in HIV. [PDF]

Trends Microbiol, 2019
Successful replication of the AIDS retrovirus, HIV, requires that its genomic RNA be packaged in assembling virus particles with high fidelity. However, cellular mRNAs can also be packaged under some conditions. Viral RNA (vRNA) contains a 'packaging signal' (ψ) and is packaged as a dimer, with two vRNA monomers joined by a limited number of base pairs.
Rein A.
europepmc   +4 more sources