Results 11 to 20 of about 2,070,961 (352)
Trends Microbiol, 2019 Successful replication of the AIDS retrovirus, HIV, requires that its genomic RNA be packaged in assembling virus particles with high fidelity. However, cellular mRNAs can also be packaged under some conditions. Viral RNA (vRNA) contains a 'packaging signal' (ψ) and is packaged as a dimer, with two vRNA monomers joined by a limited number of base pairs.
Rein A.
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Coronavirus genomic RNA packaging. [PDF]
Virology, 2019 RNA viruses carry out selective packaging of their genomes in a variety of ways, many involving a genomic packaging signal. The first coronavirus packaging signal was discovered nearly thirty years ago, but how it functions remains incompletely understood.
Masters PS.
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Dimerisation of HIV-2 genomic RNA is linked to efficient RNA packaging, normal particle maturation and viral infectivity [PDF]
Retrovirology, 2007 Background Retroviruses selectively encapsidate two copies of their genomic RNA, the Gag protein binding a specific RNA motif in the 5' UTR of the genome. In human immunodeficiency virus type 2 (HIV-2), the principal packaging signal (Psi) is upstream of
Crowther R Anthony +3 more
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RNA Structures and Their Role in Selective Genome Packaging [PDF]
Viruses, 2021 To generate infectious viral particles, viruses must specifically select their genomic RNA from milieu that contains a complex mixture of cellular or non-genomic viral RNAs.
Liqing Ye +7 more
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The impact of local assembly rules on RNA packaging in a T = 1 satellite plant virus. [PDF]
PLoS Computational Biology, 2021 The vast majority of viruses consist of a nucleic acid surrounded by a protective icosahedral protein shell called the capsid. During viral infection of a host cell, the timing and efficiency of the assembly process is important for ensuring the ...
Sam R Hill +2 more
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Host RNA Packaging by Retroviruses: A Newly Synthesized Story. [PDF]
mBio, 2016 A fascinating aspect of retroviruses is their tendency to nonrandomly incorporate host cell RNAs into virions. In addition to the specific tRNAs that prime reverse transcription, all examined retroviruses selectively package multiple host cell noncoding ...
Eckwahl MJ, Telesnitsky A, Wolin SL.
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Packaging of Genomic RNA in Positive-Sense Single-Stranded RNA Viruses: A Complex Story
Viruses, 2019 The packaging of genomic RNA in positive-sense single-stranded RNA viruses is a key part of the viral infectious cycle, yet this step is not fully understood. Unlike double-stranded DNA and RNA viruses, this process is coupled with nucleocapsid assembly.
Mauricio Comas-Garcia
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RNA Encapsidation and Packaging in the Phleboviruses [PDF]
Viruses, 2016 The Bunyaviridae represents the largest family of segmented RNA viruses, which infect a staggering diversity of plants, animals, and insects. Within the family Bunyaviridae, the Phlebovirus genus includes several important human and animal pathogens ...
Katherine E. Hornak +2 more
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Nucleocapsid proteins: roles beyond viral RNA packaging. [PDF]
Wiley Interdiscip Rev RNA, 2016 Viral nucleocapsid proteins (NCs) enwrap the RNA genomes of viruses to form NC–RNA complexes, which act as a template and are essential for viral replication and transcription.
Ding B, Qin Y, Chen M.
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Kinetic Studies on the Interaction of HIV-1 Gag Protein with the HIV-1 RNA Packaging Signal [PDF]
VirusesDuring HIV-1 virus assembly, the genomic RNA (vRNA) is selected for packaging by the viral protein Gag because it contains a specific packaging signal, Psi. While there have been numerous studies of Gag–Psi interactions, there is almost no information on
Constance Rink +3 more
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