Results 31 to 40 of about 2,070,961 (352)
Disruption of Specific RNA-RNA Interactions in a Double-Stranded RNA Virus Inhibits Genome Packaging and Virus Infectivity. [PDF]
PLoS Pathogens, 2015 Bluetongue virus (BTV) causes hemorrhagic disease in economically important livestock. The BTV genome is organized into ten discrete double-stranded RNA molecules (S1-S10) which have been suggested to follow a sequential packaging pathway from smallest ...
Teodoro Fajardo, Po-Yu Sung, Polly Roy
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Reovirus Low-Density Particles Package Cellular RNA
Viruses, 2021 Packaging of segmented, double-stranded RNA viral genomes requires coordination of viral proteins and RNA segments. For mammalian orthoreovirus (reovirus), evidence suggests either all ten or zero viral RNA segments are simultaneously packaged in a ...
Timothy W. Thoner +3 more
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Packaging signal of influenza A virus
Virology Journal, 2021 Influenza A virus (IAV) contains a genome with eight single-stranded, negative-sense RNA segments that encode 17 proteins. During its assembly, all eight separate viral RNA (vRNA) segments are incorporated into virions in a selective manner.
Xiuli Li +4 more
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Specificity of retroviral RNA packaging [PDF]
Journal of Virology, 1991 Encapsidation of retroviral RNA has been shown to be dependent on specific cis-acting signals, in particular, the packaging region (psi) located near the 5' end of the retroviral genome. In this report, we show that a 683-base avian extended packaging sequence (psi+) derived from Rous sarcoma virus will direct packaging of heterologous hygromycin mRNA ...
Maxine L. Linial, Rachel Aronoff
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Modified RNAs and predictions with the ViennaRNA Package
Bioinformatics, 2023 Abstract Motivation In living organisms, many RNA molecules are modified post-transcriptionally. This turns the widely known four-letter RNA alphabet ACGU into a much larger one with currently more than 300 known distinct modified bases.
Varenyk, Yuliia +3 more
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RNA Origami: Packaging a Segmented Genome in Orbivirus Assembly and Replication
Viruses, 2021 Understanding how viruses with multi-segmented genomes incorporate one copy of each segment into their capsids remains an intriguing question. Here, we review our recent progress and describe the advancements made in understanding the genome packaging ...
Po-Yu Sung, Polly Roy
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Frontiers in Cellular and Infection Microbiology, 2023 Rift Valley fever virus (RVFV), a bunyavirus, has a single-stranded, negative-sense tri-segmented RNA genome, consisting of L, M and S RNAs. An infectious virion carries two envelope glycoproteins, Gn and Gc, along with ribonucleoprotein complexes ...
Breanna Tercero +8 more
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Packaging of viral RNAs in virions of adenoviruses [PDF]
Virology Journal, 2009 Earlier, we detected viral RNAs packaged in the porcine adenovirus (PAdV) -3 virions. Using Southern blot analysis, we further demonstrated that the viral RNAs were predominantly packaged in CsCl purified mature capsids (containing viral genome) than empty/intermediate capsids. Some of the packaged viral RNAs appear to be polyadenylated.
Li Xing, Suresh K. Tikoo
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Sorting and packaging of RNA into extracellular vesicles shape intracellular transcript levels
BMC Biology, 2022 Background Extracellular vesicles (EVs) are released by nearly every cell type and have attracted much attention for their ability to transfer protein and diverse RNA species from donor to recipient cells.
Tina M. O’Grady +8 more
semanticscholar +1 more source
RNA packaging in lentiviruses [PDF]
Retrovirology, 2009 The selection by a lentivirus of its genomic RNA from the background of a vast excess of cellular messenger RNAs and sub-genomic viral RNAs occurs with high specificity. The nature and site of the specific interaction between the unspliced RNA genome and the gag polyprotein, which is responsible for its capture, is still poorly understood and the ...
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