Results 1 to 10 of about 1,280,482 (239)
Single-peptide DNA-dependent RNA polymerase homologous to multi-subunit RNA polymerase [PDF]
Nature Communications, 2017 Although all known RNA polymerases have multiple subunits, unrelated single-subunit polymerases have also been described. Here, the authors describe a single-subunit RNA polymerase from the SPβ prophage ofBacillus subtilis, which shares homology to multi-
David Forrest +3 more
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Structure of the bacteriophage PhiKZ non-virion RNA polymerase bound to a p119L open promoter analogue [PDF]
IUCrJBacteriophage ΦKZ (PhiKZ) was the first identified member of a family of massive bacterial viruses. ΦKZ infects Pseudomonas aeruginosa, which kills tens of thousands every year, and it therefore has potential as a bacteriophage therapy. On infection, ΦKZ
Chao-Sheng Chen +3 more
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Guanine quadruplexes mediate mitochondrial RNA polymerase pausing [PDF]
BMC BiologyBackground The information content within nucleic acids extends beyond the primary sequence to include secondary structures with functional roles in transcription regulation.
Ryan J. Snyder +6 more
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Abstract P-23: Histone N-terminal Tails Reduce Early Nucleosomal Pausing during Transcription [PDF]
International Journal of Biomedicine, 2021 Background: Nucleosomes are the barriers to transcript elongation by RNA polymerase 2 (Pol 2) in vitro and in vivo. Formation and overcoming the barrier are important for transcription regulation. N-terminal tails of core histones do not affect the inner
Nadezhda S. Gerasimova +2 more
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Abstract P-18: Phosphorylation of RNA Polymerase II C-Terminal Domain Affects Transcript Elongation Through Chromatin [PDF]
International Journal of Biomedicine, 2021 Background: Transcription is the central point of gene regulation where the efficient maintenance of chromatin structure during the passage of RNA polymerase (Pol II) is critical for cell survival and functioning.
Sohail Akhtar +3 more
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Extragenic accumulation of RNA polymerase II enhances transcription by RNA polymerase III. [PDF]
PLoS Genetics, 2007 Recent genomic data indicate that RNA polymerase II (Pol II) function extends beyond conventional transcription of primarily protein-coding genes. Among the five snRNAs required for pre-mRNA splicing, only the U6 snRNA is synthesized by RNA polymerase ...
Imke Listerman +3 more
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Biotechnology & Biotechnological Equipment, 2021 Yeasts Saccharomyces cerevisiae, like other microbes in nature, respond to the unavailability of nutrients with entrance in quiescent/G0 state. These cells exist in non-dividing, latent form by maintaining the cellular metabolism at a low level but still
Asya Vladimirova Daskalova +5 more
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DNA polymerase III protein, HolC, helps resolve replication/transcription conflicts
Microbial Cell, 2021 In Escherichia coli, DNA replication is catalyzed by an assembly of proteins, the DNA polymerase III holoenzyme. This complex includes the polymerase and proofreading subunits, the processivity clamp and clamp loader complex.
Susan T. Lovett
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Biophysical Chemistry, 2011 Molecular motors can exhibit Brownian ratchet or power stroke mechanisms. These mechanistic categories are related to transition state position: An early transition state suggests that chemical energy is stored and then released during the step (stroke) while a late transition state suggests that the release of chemical energy rectifies thermally ...
Galburt, E., Parrondo, J., Grill, S.
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RNA Polymerases of Maize: Nuclear RNA Polymerases [PDF]
Proceedings of the National Academy of Sciences, 1971 Two DNA-dependent RNA polymerases of nuclear origin have been purified from leaves of Zea mays . The two enzymes can be separated on DEAE-cellulose columns. Enzymes I and II are eluted with 0.08 and 0.20 M (NH 4 ) 2 SO 4 , respectively.
G C, Strain, K P, Mullinix, L, Bogorad
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