Results 191 to 200 of about 991,885 (339)

Transcription elongation factor SII interacts with a domain of the large subunit of human RNA polymerase II. [PDF]

, 1988
Jay Rappaport, K Cho, Alan Saltzman, Joseph Prenger, Miriam Golomb, Roberto Weinmann   +5 more
openalex   +1 more source

Vibration‐Mediated Recovery of Irradiated Osteocytes and Their Regulatory Role in Breast Cancer Bone Metastasis

Advanced Healthcare Materials, EarlyView.
Radiotherapy damages bone and disrupts osteocyte function, yet mechanically mediated protection remains largely unexplored. This study demonstrates that low‐magnitude, high‐frequency (LMHF) vibration mitigates irradiated osteocyte apoptosis, restores their ability to regulate breast cancer extravasation, and acts synergistically with radiotherapy to ...
Xin Song, Kimberly Seaman, Amel Sassi, Chun‐Yu Lin, Tiankuo Chu, Liyun Wang, Yu Sun, Lidan You   +7 more
wiley   +1 more source

DNA-directed termination of mammalian RNA polymerase II. [PDF]

Genes Dev
Davidson L, Rouvière JO, Sousa-Luís R, Nojima T, Proudfoot NJ, Jensen TH, West S.   +6 more
europepmc   +2 more sources

Multi-omics analysis reveals RNA polymerase II degradation as a novel mechanism of PF-3758309's anti-tumor activity. [PDF]

Cell Death Discov
Jia X, Zhang J, Pan L, He J, Zhu M, Zhao L, Zhang X, Zhao W, Xie D, Shen X, Liu B, Tan M.   +11 more
europepmc   +1 more source

Poly(dAT) dependent trinucleotide synthesis catalysed by wheat germ RNA polymerase II. Effects of nucleotide substrates and cordycepin triphosphate [PDF]

, 1985
Jacques Dietrich, Marcel Teissère, Claudette Job, Dominique Job   +3 more
openalex   +1 more source

RNA polymerase II clustering through carboxy-terminal domain phase separation

Nature Structural & Molecular Biology, 2018
M. Boehning, C. Dugast-Darzacq, M. Rankovic, A. Hansen, Taekyung Yu, H. Marie-Nelly, D. McSwiggen, G. Kokic, G. Dailey, P. Cramer, X. Darzacq, M. Zweckstetter   +11 more
semanticscholar   +1 more source

Impact of Nanoparticle Stiffness on Endosomal Escape and Signaling Pathways in Cytosolic Delivery

Advanced Healthcare Materials, EarlyView.
Nanoparticle (NP) stiffness affects cellular uptake, but its impact on intracellular distribution remains unclear. This study synthesizes silica nanocapsules with varying stiffness, inspired by viral mechanisms, and applies assays to measure cellular uptake and escape efficiency.
Yali Zhang, Yue Hui, Zichao Guo, Dawei Liu, Yun Liu, Huajian Gao, Chun‐Xia Zhao   +6 more
wiley   +1 more source

BACTERIOPHAGE T4 ENDONUCLEASES II AND IV, OPPOSITELY AFFECTED BY dCMP HYDROXYMETHYLASE ACTIVITY, HAVE DIFFERENT ROLES IN THE DEGRADATION AND IN THE RNA POLYMERASE-DEPENDENT REPLICATION OF T4 CYTOSINE-CONTAINING DNA [PDF]

, 1986
Karin Carlson, Aud Ȗvervatin
openalex   +1 more source

A Human Kidney Tubuloid Model of Repeated Cisplatin‐Induced Cellular Senescence and Fibrosis for Drug Screening

Advanced Healthcare Materials, EarlyView.
Replicating aging and senescence‐related pathophysiological responses in kidney organoids remains a significant challenge. Human adult renal tubular organoid, tubuloids, are successfully developed recapitulating cellular senescence that is the central pathophysiological mechanism of chronic kidney disease (CKD).
Yuki Nakao, Makiko Mori, Yuta Sekiguchi, Iori Morita, Ryota Shindoh, Shintaro Mandai, Tamami Fujiki, Hiroaki Kikuchi, Fumiaki Ando, Koichiro Susa, Takayasu Mori, Ayumi Suzuki, Yuji Nashimoto, Hirokazu Kaji, Yuma Waseda, Soichiro Yoshida, Yasuhisa Fujii, Eisei Sohara, Shinichi Uchida, Kensuke Miyake, Yutaro Mori   +20 more
wiley   +1 more source

Phosphorylation modulates secondary structure of intrinsically disorder regions in RNA polymerase II. [PDF]

J Biol Chem
Chen W, Laremore TN, Yennawar NH, Showalter SA.   +3 more
europepmc   +1 more source