Results 261 to 270 of about 821,958 (335)

DNA-directed termination of mammalian RNA polymerase II. [PDF]

Genes Dev
Davidson L, Rouvière JO, Sousa-Luís R, Nojima T, Proudfoot NJ, Jensen TH, West S.   +6 more
europepmc   +2 more sources

Direct recruitment of RNA Polymerase II by NANOG to activated target genes

Mullin NP, Barbieri E, Zhang J, Vojtek M, McGarvey A, Colby D, Tomlinson S, Chambers IP.   +7 more
europepmc   +1 more source

RNA polymerase II at histone genes predicts outcome in human cancer. [PDF]

Science
Henikoff S, Zheng Y, Paranal RM, Xu Y, Greene JE, Henikoff JG, Russell ZR, Szulzewsky F, Thirimanne HN, Kugel S, Holland EC, Ahmad K.   +11 more
europepmc   +1 more source

Evaluating Cytocompatibility of Corynebacterium glutamicum‐poly Vinyl Alcohol Living Biomaterials for Ocular Use

Advanced Healthcare Materials, EarlyView.
In ophthalmology, living biomaterials such as living contact lenses appear promising for sustained drug delivery or biosensing. The cytocompatibility of Cg‐PVA hydrogels, developed as a model living contact lens, is investigated with the ocular surface, showing their potential translation to the clinic.
Krupansh Desai, Lorely Garcia‐Sanchez, Maryam Amini, Lara Luana Teruel‐Enrico, Silke Siegrist, Aránzazu del Campo, Sara Trujillo   +6 more
wiley   +1 more source

RNA polymerase II coordinates histone deacetylation at active promoters. [PDF]

Sci Adv
Hoffman JA, Trotter KW, Archer TK.
europepmc   +1 more source

Redefining Therapies for Drug‐Resistant Tuberculosis: Synergistic Effects of Antimicrobial Peptides, Nanotechnology, and Computational Design

Advanced Healthcare Materials, EarlyView.
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales, Jessica Ingrid Marquez Cazorla, Renzo Marianito Marquez Cazorla, Aline Martins dos Santos, Jonatas Lobato Duarte, Letícia Oliveira Catarin Nunes, Túlio Custódio Reis, Lara Cerazi Salvador, Norival Alves Santos‐Filho, Rafael Miguel Sábio, Hélder A. Santos, Fernando Rogério Pavan   +11 more
wiley   +1 more source

Phosphorylation modulates secondary structure of intrinsically disorder regions in RNA polymerase II. [PDF]

J Biol Chem
Chen W, Laremore TN, Yennawar NH, Showalter SA.   +3 more
europepmc   +1 more source

Evaluating the Antiviral Efficacy of Encapsulated PKC Inhibitor BIM‐I against influenza A Virus Infection

Advanced Healthcare Materials, EarlyView.
This study explores nanoparticle delivery of the protein kinase C inhibitor bisindolylmaleimide‐I (BIM‐I) to combat influenza A virus infections. Encapsulation in biodegradable PLGA nanoparticles improved safety while maintaining the compound's strong antiviral activity.
Laura Klement, Jana Ismail, Josefine Schroeder, Amod Godbole, Johanna Schreiber, Christine Weber, Zoltan Cseresnyes, Marc T. Figge, Bettina Löffler, Ulrich S. Schubert, Stephanie Schubert, Christina Ehrhardt, Carsten Hoffmann   +12 more
wiley   +1 more source

Mouse promoters are characterised by low occupancy and high turnover of RNA polymerase II. [PDF]

Mol Syst Biol
Chatsirisupachai K, Moene CJI, Kleinendorst R, Kreibich E, Molina N, Krebs A.   +5 more
europepmc   +1 more source

Mechanisms and Functions of the RNA Polymerase II General Transcription Machinery during the Transcription Cycle [PDF]

Stephen R. Archuleta, James A. Goodrich, Jennifer F. Kugel   +2 more
openalex   +1 more source