Results 261 to 270 of about 991,885 (339)

Damage Microenvironment Guided Responsive Smart Hydrogel Design for Self‐Regenerative Repair in Chronic Wound Healing

open access: yesAdvanced Materials Interfaces, EarlyView.
Chronic wounds remain a major therapeutic challenge, with VEGF applications hindered by rapid degradation and systemic side effects. Here, a dual‐responsive chitosan–gelatin hydrogel is reported, functionalized with dopamine, glutathione, and MMP‐sensitive motifs, enabling spatiotemporally controlled VEGF release and enhanced biocompatibility, thereby ...
Zhenghui Xiong   +5 more
wiley   +1 more source

3D‐Printed Unibody Microfluidic Devices for Organ‐on‐Chip Applications

open access: yesAdvanced Materials Technologies, EarlyView.
A practical approach is demonstrated to 3D printing unibody microfluidic Organ‐on‐Chip (OoC) devices using commercial resins and desktop DLP printers. The demonstrated functional devices support 2D monolayers, 3D spheroids, and barrier tissues. With optimised design and post‐processing techniques, leak‐free, biocompatible microchannels and membranes ...
Louis Jun Ye Ong   +8 more
wiley   +1 more source

Implementation of FTA Elute Card for Viral RNA Storage and Cost‐Effective Wastewater Surveillance

open access: yesAdvanced Sensor Research, EarlyView.
A strategy is developed for room‐temperature storage of RNA from wastewater using FTA Elute cards, which allow for easy and portable transportation. FTA Elude cards provided a 15.4% recovery of the original RNA with cards, compared to only 0.5% recovery without cards.
Qingxin Hui   +3 more
wiley   +1 more source

Mechanisms of transcription attenuation and condensation of RNA polymerase II by RECQ5

open access: yes
Sebesta M   +10 more
europepmc   +1 more source

Spt6-Spn1 interaction is required for RNA polymerase II association and precise nucleosome positioning along transcribed genes. [PDF]

open access: yesJ Biol Chem
Chen B   +9 more
europepmc   +1 more source

Gallium β‐Cyclodextrin Nanoparticles Containing both Gallium Protoporphyrin and Gallium Nitrate Exhibit Antimicrobial Activity against Nontuberculous Mycobacteria in Vitro and in Vivo

open access: yesAdvanced Therapeutics, EarlyView.
Cyclodextrin nanoparticle containing both Ga(NO3)3 and GaPP is synthesized and tested against non‐tuberculous mycobacteria (NTM). The in vivo efficacy of the nanoparticle therapy is additionally tested by treating pulmonary NTM infections in mice and observed much greater effectiveness in bacterial clearance and survival of mice.
Seoung‐ryoung Choi   +2 more
wiley   +1 more source

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