Results 31 to 40 of about 340,586 (247)
Retrotransposon targeting to RNA polymerase III-transcribed genes
Mobile DNA, 2018 Retrotransposons are genetic elements that are similar in structure and life cycle to retroviruses by replicating via an RNA intermediate and inserting into a host genome. The Saccharomyces cerevisiae (S.
Stephanie Cheung +2 more
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BMC Evolutionary Biology, 2004 Background The primate-specific Alu elements, which originated 65 million years ago, exist in over a million copies in the human genome. These elements have been involved in genome shuffling and various diseases not only through retrotransposition but ...
Brahmachari Samir K +3 more
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European Journal of Biochemistry, 1993 Recent studies on RNA polymerase III (pol III) gene transcription have provided a new awareness of the molecular complexity of this process. Fortunately, while the number of transcription components has been increasing, fundamental similarities have emerged regarding the function of eukaryotic promoter elements and the factors that bind them to form ...
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RNA polymerase III transcription and cancer [PDF]
Oncogene, 2004 RNA polymerase (pol) III synthesizes a range of essential products, including tRNA, 5S rRNA and 7SL RNA, which are required for protein synthesis and trafficking. High rates of pol III transcription are necessary for cells to sustain growth. A wide range of transformed and tumour cell types have been shown to express elevated levels of pol III products.
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RNA polymerase III transcription as a disease factor [PDF]
Genes & Development, 2020 RNA polymerase (Pol) III is responsible for transcription of different noncoding genes in eukaryotic cells, whose RNA products have well-defined functions in translation and other biological processes for some, and functions that remain to be defined for others. For all of them, however, new functions are being described.
Yeganeh, M., Hernandez, N.
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RNA polymerase III transcription in cancer: the BRF2 connection
Molecular Cancer, 2011 RNA polymerase (pol) III transcription is responsible for the transcription of small, untranslated RNAs involved in fundamental metabolic processes such mRNA processing (U6 snRNA) and translation (tRNAs).
Schramm Laura, Cabarcas Stephanie
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Novel layers of RNA polymerase III control affecting tRNA gene transcription in eukaryotes [PDF]
Open Biology, 2017 RNA polymerase III (Pol III) transcribes a limited set of short genes in eukaryotes producing abundant small RNAs, mostly tRNA. The originally defined yeast Pol III transcriptome appears to be expanding owing to the application of new methods.
Ewa Leśniewska, Magdalena Boguta
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TLS Inhibits RNA Polymerase III Transcription [PDF]
Molecular and Cellular Biology, 2010 RNA transcription by all the three RNA polymerases (RNAPs) is tightly controlled, and loss of regulation can lead to, for example, cellular transformation and cancer. While most transcription factors act specifically with one polymerase, a small number have been shown to affect more than one polymerase to coordinate overall levels of transcription in ...
Adelene Y, Tan, James L, Manley
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Maf1 and Repression of RNA Polymerase III-Mediated Transcription Drive Adipocyte Differentiation
Cell Reports, 2018 Summary: RNA polymerase (pol) III transcribes a variety of small untranslated RNAs involved in transcription, RNA processing, and translation. RNA pol III and its components are altered in various human developmental disorders, yet their roles in cell ...
Chun-Yuan Chen +5 more
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BioTechniques, 2001 The RNA polymerase III-based two-hybrid system has been developed to detect interactions between proteins such as RNA polymerase II transcription factors and regulators that cannot be studied by the original RNA polymerase II two-hybrid system.
Michael Petrascheck +2 more
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