Results 21 to 30 of about 331,347 (206)
A direct role of RNA polymerase III and RNA in DNA homologous recombination
Molecular & Cellular Oncology, 2021 End resection excises several thousand bases from the 5ʹ-ended strand during DNA double-strand break repair, creating 3ʹ-end single-stranded DNA overhangs. This overhang requires strict protection from DNA2 or other nucleases digestion.
Sijie Liu, Daochun Kong
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Frontiers in Cellular and Infection Microbiology, 2022 Ancestral RNA polymerase III (Pol III) is a multi-subunit polymerase responsible for transcription of short non-coding RNA, such as double-stranded short interspersed nuclear elements (SINEs).
Brianna M. Doratt +8 more
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In vitro Assessment of RNA Polymerase I Activity
Bio-Protocol, 2017 In eukaryotic cells transcriptional processes are carried out by three different RNA polymerases: RNA polymerase I which specifically transcribes ribosomal RNA (rRNA), RNA polymerase II which transcribes protein-coding genes to yield messenger RNAs ...
Marzia Govoni
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Specific Features of RNA Polymerases I and III: Structure and Assembly
Frontiers in Molecular Biosciences, 2021 RNA polymerase I (RNAPI) and RNAPIII are multi-heterogenic protein complexes that specialize in the transcription of highly abundant non-coding RNAs, such as ribosomal RNA (rRNA) and transfer RNA (tRNA).
Tomasz W. Turowski +2 more
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Truncated PARP1 mediates ADP-ribosylation of RNA polymerase III for apoptosis
Cell Discovery, 2022 Caspase-mediated cleavage of PARP1 is a surrogate marker for apoptosis. However, the biological significance of PARP1 cleavage during apoptosis is still unclear.
Qian Chen +7 more
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Retrotransposon targeting to RNA polymerase III-transcribed genes
Mobile DNA, 2018 Retrotransposons are genetic elements that are similar in structure and life cycle to retroviruses by replicating via an RNA intermediate and inserting into a host genome. The Saccharomyces cerevisiae (S.
Stephanie Cheung +2 more
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BMC Evolutionary Biology, 2004 Background The primate-specific Alu elements, which originated 65 million years ago, exist in over a million copies in the human genome. These elements have been involved in genome shuffling and various diseases not only through retrotransposition but ...
Brahmachari Samir K +3 more
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Novel layers of RNA polymerase III control affecting tRNA gene transcription in eukaryotes [PDF]
Open Biology, 2017 RNA polymerase III (Pol III) transcribes a limited set of short genes in eukaryotes producing abundant small RNAs, mostly tRNA. The originally defined yeast Pol III transcriptome appears to be expanding owing to the application of new methods.
Ewa Leśniewska, Magdalena Boguta
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RNA polymerase III transcription in cancer: the BRF2 connection
Molecular Cancer, 2011 RNA polymerase (pol) III transcription is responsible for the transcription of small, untranslated RNAs involved in fundamental metabolic processes such mRNA processing (U6 snRNA) and translation (tRNAs).
Schramm Laura, Cabarcas Stephanie
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Maf1 and Repression of RNA Polymerase III-Mediated Transcription Drive Adipocyte Differentiation
Cell Reports, 2018 Summary: RNA polymerase (pol) III transcribes a variety of small untranslated RNAs involved in transcription, RNA processing, and translation. RNA pol III and its components are altered in various human developmental disorders, yet their roles in cell ...
Chun-Yuan Chen +5 more
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