Results 11 to 20 of about 340,586 (247)
Structure of human RNA polymerase III [PDF]
Nature Communications, 2020 The eukaryotic RNA Polymerase III transcribes tRNAs, some ribosomal and spliceosomal RNAs. Here, the authors resolve a cryo-EM structure of human RNA Polymerase III in its apo form and complemented it with crystal structures and SAXS analysis of RPC5 ...
Ewan Phillip Ramsay +10 more
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Extragenic accumulation of RNA polymerase II enhances transcription by RNA polymerase III. [PDF]
PLoS Genetics, 2007 Recent genomic data indicate that RNA polymerase II (Pol II) function extends beyond conventional transcription of primarily protein-coding genes. Among the five snRNAs required for pre-mRNA splicing, only the U6 snRNA is synthesized by RNA polymerase ...
Imke Listerman +3 more
doaj +6 more sources
Corrigendum: RNA Polymerase III, Ageing and Longevity [PDF]
Frontiers in Genetics, 2021 Yavuz Kulaberoglu +5 more
doaj +2 more sources
The RNA polymerase III–RIG-I axis in antiviral immunity and inflammation [PDF]
Trends in Immunology, 2023 Filomeen Haerynck, Michaela Gack
exaly +2 more sources
RNA Polymerase III Subunit Mutations in Genetic Diseases
Frontiers in Molecular Biosciences, 2021 RNA polymerase (Pol) III transcribes small untranslated RNAs such as 5S ribosomal RNA, transfer RNAs, and U6 small nuclear RNA. Because of the functions of these RNAs, Pol III transcription is best known for its essential contribution to RNA maturation ...
Elisabeth Lata +7 more
doaj +1 more source
Regulation of Eukaryotic RNAPs Activities by Phosphorylation
Frontiers in Molecular Biosciences, 2021 Evolutionarily conserved kinases and phosphatases regulate RNA polymerase II (RNAPII) transcript synthesis by modifying the phosphorylation status of the carboxyl-terminal domain (CTD) of Rpb1, the largest subunit of RNAPII.
Araceli González-Jiménez +5 more
doaj +1 more source
A structural perspective of human RNA polymerase III. [PDF]
RNA Biol, 2022 RNA polymerase III (Pol III) is a large multisubunit complex conserved in all eukaryotes that plays an essential role in producing a variety of short non-coding RNAs, such as tRNA, 5S rRNA and U6 snRNA transcripts. Pol III comprises of 17 subunits in both yeast and human with a 10-subunit core and seven peripheral subunits.
Wang Q, Lei M, Wu J.
europepmc +4 more sources
Subcellular localization shapes the fate of RNA polymerase III
Cell Reports, 2023 Summary: RNA polymerase III (Pol III) plays a vital role in transcription and as a viral-DNA sensor, but how it is assembled and distributed within cells remains poorly understood.
Kai Tian +4 more
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Recruitment of RNA polymerase III in vivo [PDF]
Nucleic Acids Research, 2008 RNA polymerase (pol) III contains a dissociable subcomplex that is required for initiation, but not for elongation or termination of transcription. This subcomplex is composed of subunits RPC3, RPC6 and RPC7, and interacts with TFIIIB, a factor that is necessary and sufficient to support accurate pol III transcription in vitro. Direct binding of TFIIIB
Kenneth, Niall S. +2 more
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Alteration of the Premature tRNA Landscape by Gammaherpesvirus Infection
mBio, 2020 Transfer RNAs (tRNAs) are transcribed by RNA polymerase III (RNAPIII) and play a central role in decoding our genome, yet their expression and noncanonical function remain understudied.
Jessica M. Tucker +3 more
doaj +1 more source