Results 11 to 20 of about 331,347 (206)

Corrigendum: RNA Polymerase III, Ageing and Longevity [PDF]

Frontiers in Genetics, 2021
Yavuz Kulaberoglu, Yasir Malik, Gillian Borland, Colin Selman, Nazif Alic, Jennifer M. A. Tullet   +5 more
doaj   +2 more sources

The RNA polymerase III–RIG-I axis in antiviral immunity and inflammation [PDF]

Trends in Immunology, 2023
Leslie Naesens, Filomeen Haerynck, Michaela U Gack   +2 more
exaly   +2 more sources

Extragenic accumulation of RNA polymerase II enhances transcription by RNA polymerase III. [PDF]

PLoS Genetics, 2007
Recent genomic data indicate that RNA polymerase II (Pol II) function extends beyond conventional transcription of primarily protein-coding genes. Among the five snRNAs required for pre-mRNA splicing, only the U6 snRNA is synthesized by RNA polymerase ...
Imke Listerman, Anita S Bledau, Inna Grishina, Karla M Neugebauer   +3 more
doaj   +1 more source

RNA Polymerase III Subunit Mutations in Genetic Diseases

Frontiers in Molecular Biosciences, 2021
RNA polymerase (Pol) III transcribes small untranslated RNAs such as 5S ribosomal RNA, transfer RNAs, and U6 small nuclear RNA. Because of the functions of these RNAs, Pol III transcription is best known for its essential contribution to RNA maturation ...
Elisabeth Lata, Karine Choquet, Francis Sagliocco, Bernard Brais, Geneviève Bernard, Geneviève Bernard, Geneviève Bernard, Martin Teichmann   +7 more
doaj   +1 more source

Regulation of Eukaryotic RNAPs Activities by Phosphorylation

Frontiers in Molecular Biosciences, 2021
Evolutionarily conserved kinases and phosphatases regulate RNA polymerase II (RNAPII) transcript synthesis by modifying the phosphorylation status of the carboxyl-terminal domain (CTD) of Rpb1, the largest subunit of RNAPII.
Araceli González-Jiménez, Adrián Campos, Francisco Navarro, Francisco Navarro, Andrés Clemente-Blanco, Olga Calvo   +5 more
doaj   +1 more source

Subcellular localization shapes the fate of RNA polymerase III

Cell Reports, 2023
Summary: RNA polymerase III (Pol III) plays a vital role in transcription and as a viral-DNA sensor, but how it is assembled and distributed within cells remains poorly understood.
Kai Tian, Rui Wang, Jie Huang, Hui Wang, Xiong Ji   +4 more
doaj   +1 more source

Structure of human RNA polymerase III

Nature Communications, 2020
The eukaryotic RNA Polymerase III transcribes tRNAs, some ribosomal and spliceosomal RNAs. Here, the authors resolve a cryo-EM structure of human RNA Polymerase III in its apo form and complemented it with crystal structures and SAXS analysis of RPC5 ...
Ewan Phillip Ramsay, Guillermo Abascal-Palacios, Julia L. Daiß, Helen King, Jerome Gouge, Michael Pilsl, Fabienne Beuron, Edward Morris, Philip Gunkel, Christoph Engel, Alessandro Vannini   +10 more
doaj   +1 more source

Manipulation of RNA polymerase III by Herpes Simplex Virus-1

Nature Communications, 2022
RNA Polymerase III (Pol III) transcribes non-coding RNA, including tRNAs. Applying different RNA-Seq techniques, Dremel et al. provide the Pol III transcriptional landscape of Herpes simplex virus 1 (HSV-1) infected cells.
Sarah E. Dremel, Frances L. Sivrich, Jessica M. Tucker, Britt A. Glaunsinger, Neal A. DeLuca   +4 more
doaj   +1 more source

Alteration of the Premature tRNA Landscape by Gammaherpesvirus Infection

mBio, 2020
Transfer RNAs (tRNAs) are transcribed by RNA polymerase III (RNAPIII) and play a central role in decoding our genome, yet their expression and noncanonical function remain understudied.
Jessica M. Tucker, Aaron M. Schaller, Ian Willis, Britt A. Glaunsinger   +3 more
doaj   +1 more source

Chromatin remodeling by Pol II primes efficient Pol III transcription

Nature Communications, 2023
The packaging of the genetic material into chromatin imposes the remodeling of this barrier to allow efficient transcription. RNA polymerase II activity is coupled with several histone modification complexes that enforce remodeling.
Carlo Yague-Sanz, Valérie Migeot, Marc Larochelle, François Bachand, Maxime Wéry, Antonin Morillon, Damien Hermand   +6 more
doaj   +1 more source