Results 311 to 320 of about 310,443 (357)

Vesicular and non-vesicular extracellular small RNAs direct gene silencing in a plant-interacting bacterium. [PDF]

Nat Commun
Ravet A, Zervudacki J, Singla-Rastogi M, Charvin M, Thiebeauld O, Perez-Quintero AL, Courgeon L, Candat A, Lebeau L, Fortunato AE, Mendu V, Navarro L.   +11 more
europepmc   +1 more source

Neophytadiene, a Plant Specialized Metabolite, Mediates the Virus‐Vector‐Plant Tripartite Interactions

Advanced Science, EarlyView.
Tomato chlorosis virus (ToCV) infection induces production of neophytadiene, a volatile resulting from chlorophyll degradation that is highly attractive to whiteflies. OBP2, an odorant‐binding protein from insect vector B. tabaci, exhibits a strong binding affinity for neophytadiene.
Xiao‐bin Shi, Hao Yue, Yan Wei, Evan L. Preisser, Pei Wang, Jiao Du, Ji‐xing Xia, Kai‐long Li, Xin Yang, Jian‐bin Chen, Song‐bai Zhang, Zhan‐hong Zhang, Xu‐guo Zhou, De‐yong Zhang, Yong Liu   +14 more
wiley   +1 more source

The chromatin reader Dido3 is a regulator of the gene network that controls B cell differentiation. [PDF]

Cell Biosci
Del Burgo FG, García-López MÁ, Pons T, de Luis EV, Martínez-A C, Villares R.   +5 more
europepmc   +1 more source

PLoS One [PDF]

, 2012
Alles, J., Barth, S., Cogliatti, S., Dueck, A., Grasser, F., Imig, J., Meister, G., Motsch, N., Reineke, T., Renner, C., Tinguely, M., Zhu, J.   +11 more
core   +1 more source

Pyruvate Carboxylase in Macrophages Aggravates Atherosclerosis by Regulating Metabolism Reprogramming to Promote Inflammatory Responses Through the Hypoxia‐Inducible Factor‐1 Signaling Pathway

Advanced Science, EarlyView.
This study investigates the role of macrophage pyruvate carboxylase (PC) in atherosclerosis (AS) demonstrating that PC upregulation in macrophages promotes metabolism reprogramming to enhance inflammatory responses via the HIF‐1 signaling pathway.
Ling‐Na Zhao, Rui‐Ling Wang, Ran‐Xin Liu, Meng‐Ru Zheng, Li Zhao, Bao‐Feng Li, Jia‐Le Li, De‐Shen Liu, Xiao‐Xia He, Qin‐Bao Peng, Kai Li, Tian‐Xiao Lin, Ying‐Ying Liu, Sheng‐Ping He, Jun Lu, Shao‐Yi Zheng, Xiu Liu, Fang‐Ze Huang   +17 more
wiley   +1 more source

A spatial transcriptomic signature of 26 genes resolved at single-cell resolution characterizes high-risk gastric cancer precursors. [PDF]

NPJ Precis Oncol
Huang RJ, Wichmann IA, Su A, Sathe A, Shum MV, Grimes SM, Meka R, Almeda A, Bai X, Shen J, Nguyen Q, Luo I, Han SS, Amieva MR, Hwang JH, Ji HP.   +15 more
europepmc   +1 more source

Ultrasound‐Responsive 4D Bioscaffold for Synergistic Sonopiezoelectric‐Gaseous Osteosarcoma Therapy and Enhanced Bone Regeneration

Advanced Science, EarlyView.
An acoustic‐responsive therapeutic platform for synergistic sonopiezoelectric‐gaseous osteosarcoma therapy and bone regeneration is fabricated through the joint loading of few‐layer black phosphorus nanosheets and S‐Nitroso‐L‐glutathione onto the 3D‐printed bioactive glass scaffolds.
Haoyu Fang, Daoyu Zhu, Yixuan Chen, Changqing Zhang, Gan Li, Qihang Fang, Meiqi Chang, Yu Chen, Youshui Gao   +8 more
wiley   +1 more source

The Application of Non-Coding RNAs as Biomarkers, Therapies, and Novel Vaccines in Diseases. [PDF]

Int J Mol Sci
Yang LX, Li H, Cheng ZH, Sun HY, Huang JP, Li ZP, Li XX, Hu ZG, Wang J.   +8 more
europepmc   +1 more source

METTL14‐Induced M6A Methylation Increases G6pc Biosynthesis, Hepatic Glucose Production and Metabolic Disorders in Obesity

Advanced Science, EarlyView.
It is shown that obesity is associated with increases in hepatic METTL14 and m6A methylation of G6pc transcript. YTHDF1 and YTHDF3 bind to m6A‐marked G6pc mRNA to increase its synthesis. Hepatocyte‐specific deletion of Mettl14 decreases G6pc m6A methylation, G6pc biosynthesis, and G6pc‐mediated gluconeogenesis, alleviating glucose metabolic defects in ...
Qiantao Zheng, Xiao Zhong, Qianqian Kang, Zhiguo Zhang, Decheng Ren, Yong Liu, Liangyou Rui   +6 more
wiley   +1 more source

Pus7mutation links tRNA dysregulation to aggressive behavior through activation of the integrated stress response and glycolytic reprogramming

Stock M, Angel MG, Witzenberger M, Nowak J, Biela A, Chramiec-Glabik A, Mariano V, Dreos R, Sklias A, Quadroni M, Brümmer A, Gallart-Ayala H, Ivanisevic J, Guex N, Kleenman L, Leidel S, Helm M, Bagni C, Glatt S, Gatfield D, Schwartz S, Roignant J.   +21 more
europepmc   +1 more source