Results 311 to 320 of about 324,915 (330)
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A precursor of globin messenger RNA
Journal of Molecular Biology, 1976Abstract The size of pulse-labeled globin messenger RNA nucleotide sequences was investigated, to determine whether newly transcribed globin mRNA molecules are larger than steady-state globin mRNA. Molecular hybridization techniques were used to compare directly the sedimentation of steady-state (unlabeled) and pulse-labeled (radioactive) globin mRNA
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Splicing messenger RNA precursors: branch sites and lariat RNAs
Trends in Biochemical Sciences, 1985Abstract The splicing of mRNA precursors proceeds through an unusual RNA structure: a lariat or tailed circular molecule where the 5′ end of the intervening sequence is attached to an internal residue via a 2′–5′ phosphodiester bond. The role of lariat formation and its possible significance are discussed.
Richard A. Padgett +3 more
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Asymmetric maturation of a dimeric transfer RNA precursor
Journal of Molecular Biology, 1980Abstract Six of the eight transfer RNAs coded by bacteriophage T4 are synthesized via three dimeric precursor molecules. The sequences of two of these have been determined. Both of these precursors give rise to equimolar amounts of the cognate tRNA molecules in vivo .
C, Guthrie, C A, Scholla
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Isolation of ribosomal RNA precursors from lung
Analytical Biochemistry, 1977Abstract A method is presented for the isolation of ribosomal RNA precursors from lung. The very labile precursors of ribosomal RNA in mouse lungs can be isolated and preserved when lung tissue (i) is frozen in liquid nitrogen and pulverized, (ii) is homogenized in hypotonic buffer, (iii) nuclei are rapidly isolated after being sieved through ...
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Isolation of ribosomal RNA precursors from Physarum polycephalum
Archives of Biochemistry and Biophysics, 1973Ribosomal RNA synthesis in Physarum polycephalum was studied by labeling intact microplasmodia with [3H]uridine. Labeled, high-molecular-weight RNA species were found in a 30,000 S structure released by phenol extraction at room temperature. RNA was released from the structure by further phenol extraction at 65–70 °C.
D N, Jacobson, C E, Holt
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Precursors of alpha and beta globin messenger RNAs
Journal of Molecular Biology, 1978Abstract Several structural properties of the pulse-labeled globin messenger RNA precursor molecules that sediment faster than steady-state (10 S) globin mRNA (Curtis & Weissmann, 1976; Ross, 1976; Kwan et al., 1977; Bastos & Aviv, 1977) are investigated.
J, Ross, D A, Knecht
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SPLICING OF MESSENGER RNA PRECURSORS
Annual Review of Biochemistry, 1986R A, Padgett +4 more
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Transcription and Processing of Transfer RNA Precursors
1976Publisher Summary This chapter discusses the transcription of tRNA genes as precursors and how these are converted to mature tRNA. One important step in tRNA biosynthesis, the modification of tRNA bases, is discussed only in relation to the precursors.
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Erratum: Splicing of Messenger RNA Precursors
Science, 1987In the article "Splicing of messenger RNA precursors" by Phillip A. Sharp (13 Feb., p. 766), the results of C. Weissmann ( 53 ) were incorrectly described. As H. Hornig et al. show [ Nature (London ) 324, 589 (1987)], a C at the branch site of a precursor RNA does not ...
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Nucleotide Sequence and Function of Transfer RNA and Precursor Transfer RNA
1973At present, we have to consider the functional interactions of the tRNA molecule without knowing its three-dimensional structure. Comparison of tRNA sequences has shown that they have a common hydrogen-bonded structure defined by the cloverleaf arrangement, and in addition they have certain common sequences or correlated sequences which may also be ...
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