Results 231 to 240 of about 938,495 (334)

Comparative single‐cell transcriptomic profiling of patient‐derived renal carcinoma cells in cellular and animal models of kidney cancer

open access: yesFEBS Open Bio, EarlyView.
We generated and characterized clear cell renal cell carcinoma models using the patient‐derived RCC243 cell line—including cell culture, orthotopic, and metastatic tumors—via single‐cell RNA‐sequencing for comparisons between models and patient tumor datasets.
Richard Huang   +9 more
wiley   +1 more source

RAS, a Pentatricopeptide Repeat Protein, Interacts with OsTRX z to Regulate Chloroplast Gene Transcription and RNA Processing. [PDF]

open access: yesPlants (Basel)
Qiu Z   +14 more
europepmc   +1 more source

Multi-omic profiling reveals an RNA processing rheostat that predisposes to prostate cancer. [PDF]

open access: yesEMBO Mol Med, 2023
Stentenbach M   +10 more
europepmc   +1 more source

METTL3 knockout accelerates hepatocarcinogenesis via inhibiting endoplasmic reticulum stress response

open access: yesFEBS Open Bio, EarlyView.
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui   +15 more
wiley   +1 more source

NS1-mediated DNMT1 degradation regulates human bocavirus 1 replication and RNA processing. [PDF]

open access: yesPLoS Pathog
Qin S   +10 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy