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RNA processing in prokaryotic cells
BioEssays, 1993AbstractRNA processing in Escherichia coli and some of its phages is reviewed here, with primary emphasis on rRNA and tRNA processing. Three enzymes, RNase III, RNase E and RNase P are responsible for most of the primary endonucleolytic RNA processing events. The first two are proteins, while RNase P is a ribozyme.
David Apirion, Andras Miczak
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Processing of 45 s nucleolar RNA
Journal of Molecular Biology, 1970Abstract Approximately one-half of the 45 s RNA precursor to mammalian ribosomal RNA is discarded during maturation in the nucleolus. Several intermediate size molecules are formed which have approximate sedimentation coefficients of 41, 36, 32, 24 and 20 s.
Sheldon Penman, Robert A. Weinberg
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Chloroplast RNA processing and stability
Photosynthesis Research, 2004Primary chloroplast transcripts are processed in a number of ways, including intron splicing, internal cleavage of polycistronic RNAs, and endonucleolytic or exonucleolytic cleavages at the transcript termini. All chloroplast RNAs are also subject to degradation, although a curious feature of many chloroplast mRNAs is their relative longevity.
David L. Herrin, Jöerg Nickelsen
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Telomerase RNA biosynthesis and processing
Biochemistry (Moscow), 2012Telomerase synthesizes repetitive G-rich sequences (telomeric repeats) at the ends of eukaryotic chromosomes. This mechanism maintains the integrity of the genome, as telomere shortening leads to degradation and fusion of chromosomes. The core components of telomerase are the telomerase catalytic subunit and telomerase RNA, which possesses a small ...
E. V. Gromenko +5 more
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RNA Processing and Translation
2009The information that codes for all proteins in a cell is found on specific segments within the DNA. When a cell requires the function of a particular protein, it must initiate the steps involved in the synthesis of this protein. The overall process is termed gene expression.
Nadine Wiper-Bergeron +2 more
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Trends in Biochemical Sciences, 1980
Abstract Recent studies indicate that, in addition to generating messenger RNA, RNA processing plays an important role in controlling the expression of immunoglobulin genes in the development of the immune response.
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Abstract Recent studies indicate that, in addition to generating messenger RNA, RNA processing plays an important role in controlling the expression of immunoglobulin genes in the development of the immune response.
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RNA processing and human disease
Cellular and Molecular Life Sciences, 2000Gene expression involves multiple regulated steps leading from gene to active protein. Many of these steps involve some aspect of RNA processing. Diseases caused by mutations that directly affect RNA processing are relatively rare compared with mutations that disrupt protein function.
T. A. Cooper, A. V. Philips
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Lsm proteins and RNA processing [PDF]
Biochemical Society Transactions, 2005 Sm and Lsm proteins are ubiquitous in eukaryotes and form complexes that interact with RNAs involved in almost every cellular process. My laboratory has studied the Lsm proteins in the yeast Saccharomyces cerevisiae, identifying in the nucleus and cytoplasm distinct complexes that affect pre-mRNA splicing and degradation, small nucleolar RNA, tRNA ...
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SnRNAs, SnRNPs, and RNA Processing
Annual Review of Biochemistry, 1982PERSPECTIVES AND SUMMARY . SMALL RNAs . Historical Aspects . Conservation Through Evolution . Synthesis 0/ Small RNAs ..
R Reddy +3 more
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RNA processing and decay in plastids
WIREs RNA, 2013AbstractPlastids were derived through endosymbiosis from a cyanobacterial ancestor, whose uptake was followed by massive gene transfer to the nucleus, resulting in the compact size and modest coding capacity of the extant plastid genome. Plastid gene expression is essential for plant development, but depends on nucleus‐encoded proteins recruited from ...
Alice Barkan +3 more
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