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RNA secondary structures play diverse roles in positive-sense (+) RNA virus infections, but those located with the replication protein coding sequence can be difficult to investigate.
Rong Sun +3 more
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Probing in vivo RNA Structure With Optimized DMS-MaPseq in Rice
RNA transcripts form various secondary and tertiary structures that have a wide range of regulatory functions. Several methods have been developed to profile in vivo RNA secondary structure in prokaryotes and eukaryotes.
Qiongli Jin +4 more
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After transcription, a messenger RNA (mRNA) is further post‐transcriptionally regulated by several features including RNA secondary structure and covalent RNA modifications (specifically N6‐methyladenosine, m6A). Both RNA secondary structure and m6A have
Marianne C. Kramer +8 more
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Pseudoknots in RNA secondary structures
<p>RNA molecules are sequences of nucleotides that serve as more than mere intermediaries between DNA and proteins, e.g. as catalytic molecules. Computational prediction of RNA secondary structure is among the few structure prediction problems that can be solved satisfactorily in polynomial time. Most work has been done to predict structures that
Rune B. Lyngsø +1 more
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Evolutionary Algorithm for RNA Secondary Structure Prediction Based on Simulated SHAPE Data. [PDF]
Non-coding RNAs perform a wide range of functions inside the living cells that are related to their structures. Several algorithms have been proposed to predict RNA secondary structure based on minimum free energy.
Soheila Montaseri +2 more
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Prediction of RNA Secondary Structure [PDF]
Calculations of the free energy required to close single-strand loops by formation of a base pair in double-helical nucleic acids are reported. These results can be used to estimate the free energy of particular secondary structures for a given RNA molecule under conditions of high-salt concentration.
C, Delisi, D M, Crothers
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RNA STRAND: The RNA Secondary Structure and Statistical Analysis Database
Background The ability to access, search and analyse secondary structures of a large set of known RNA molecules is very important for deriving improved RNA energy models, for evaluating computational predictions of RNA secondary structures and for a ...
Andronescu Mirela +3 more
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Secondary Structure of Subgenomic RNA M of SARS-CoV-2
SARS-CoV-2 belongs to the Coronavirinae family. Like other coronaviruses, SARS-CoV-2 is enveloped and possesses a positive-sense, single-stranded RNA genome of ~30 kb. Genomic RNA is used as the template for replication and transcription.
Marta Soszynska-Jozwiak +5 more
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RNAmute: RNA secondary structure mutation analysis tool
Background RNAMute is an interactive Java application that calculates the secondary structure of all single point mutations, given an RNA sequence, and organizes them into categories according to their similarity with respect to the wild type predicted ...
Barash Danny, Churkin Alexander
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Graph-Based Analysis of RNA Secondary Structure Similarity Comparison
In organisms, ribonucleic acid (RNA) plays an essential role. Its function is being discovered more and more. Due to the conserved nature of RNA sequences, its function mainly depends on the RNA secondary structure.
Lina Yang +5 more
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