Results 11 to 20 of about 2,532,976 (299)

Marginalized kernels for RNA sequence data analysis.

open access: yesGenome informatics. International Conference on Genome Informatics, 2002
We present novel kernels that measure similarity of two RNA sequences, taking account of their secondary structures. Two types of kernels are presented. One is for RNA sequences with known secondary structures, the other for those without known secondary structures.
Kin, Taishin, Tsuda, Koji, Asai, Kiyoshi
openaire   +3 more sources

ScanFold 2.0: a rapid approach for identifying potential structured RNA targets in genomes and transcriptomes [PDF]

open access: yesPeerJ, 2022
A major limiting factor in target discovery for both basic research and therapeutic intervention is the identification of structural and/or functional RNA elements in genomes and transcriptomes.
Ryan J. Andrews   +4 more
doaj   +2 more sources

TRANSCRIPTOMIC DIFFERENCES IN MONOZYGOTIC TWINS WITH OVARIAN CANCER

open access: yesSabiad, 2022
Objectives: The most significant barrier to treating epithelial ovarian cancer(EOC), is the late diagnosis and the emergence of chemotherapy resistance in the early stages.The ineffectiveness of standard treatment protocols in advanced-stage cases ...
Gözde Kuru Türkcan   +6 more
doaj   +1 more source

RNA Sequencing and Analysis [PDF]

open access: yesCold Spring Harbor Protocols, 2015
RNA sequencing (RNA-Seq) uses the capabilities of high-throughput sequencing methods to provide insight into the transcriptome of a cell. Compared to previous Sanger sequencing- and microarray-based methods, RNA-Seq provides far higher coverage and greater resolution of the dynamic nature of the transcriptome.
Kimberly R, Kukurba   +1 more
openaire   +2 more sources

Spatial transcriptomics of the nematode Caenorhabditis elegans using RNA tomography

open access: yesSTAR Protocols, 2021
Summary: RNA tomography or tomo-seq combines mRNA sequencing and cryo-sectioning to spatially resolve gene expression. We have adapted this method for the nematode Caenorhabditis elegans to generate anteroposterior gene expression maps at near-cellular ...
Erik S. Schild   +5 more
doaj   +1 more source

ANALYSIS OF LARGE-SCALE SEQUENCING OF SMALL RNAS [PDF]

open access: yesBiocomputing 2008, 2007
The advent of large-scale sequencing has opened up new areas of research, such as the study of Piwi-interacting small RNAs (piRNAs). piRNAs are longer than miRNAs, close to 30 nucleotides in length, involved in various functions, such as the suppression of transposons in germline. Since a large number of them (many tens of thousands) are generated from
Olson, A. J.   +4 more
openaire   +4 more sources

Discovery of RNA secondary structural motifs using sequence-ordered thermodynamic stability and comparative sequence analysis

open access: yesMethodsX, 2023
Major advances in RNA secondary structural motif prediction have been achieved in the last few years; however, few methods harness the predictive power of multiple approaches to deliver in-depth characterizations of local RNA motifs and their potential ...
Jake M. Peterson   +4 more
doaj   +1 more source

RNA Sequencing Analysis of Salivary Extracellular RNA [PDF]

open access: yes, 2016
Salivary biomarkers for disease detection, diagnostic and prognostic assessments have become increasingly well established in recent years. In this chapter we explain the current leading technology that has been used to characterize salivary non-coding RNAs (ncRNAs) from the extracellular RNA (exRNA) fraction: HiSeq from Illumina® platform for RNA ...
Majem, Blanca   +3 more
openaire   +4 more sources

SePIA: RNA and small RNA sequence processing, integration, and analysis [PDF]

open access: yesBioData Mining, 2016
Large-scale sequencing experiments are complex and require a wide spectrum of computational tools to extract and interpret relevant biological information. This is especially true in projects where individual processing and integrated analysis of both small RNA and complementary RNA data is needed.
Katherine Icay   +5 more
openaire   +3 more sources

Fast Processing RNA-Seq on Multicore Processor

open access: yesمجلة بغداد للعلوم, 2021
RNA Sequencing (RNA-Seq) is the sequencing and analysis of transcriptomes. The main purpose of RNA-Seq analysis is to find out the presence and quantity of RNA in an experimental sample under a specific condition.
Lee Jia Bin   +3 more
doaj   +1 more source

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