Results 41 to 50 of about 1,743,892 (345)

ScanFold: an approach for genome-wide discovery of local RNA structural elements—applications to Zika virus and HIV [PDF]

PeerJ, 2018
In addition to encoding RNA primary structures, genomes also encode RNA secondary and tertiary structures that play roles in gene regulation and, in the case of RNA viruses, genome replication.
Ryan J. Andrews, Julien Roche, Walter N. Moss   +2 more
doaj   +2 more sources

Three-dimensional modeling of single stranded DNA hairpins for aptamer-based biosensors. [PDF]

, 2017
Aptamers consist of short oligonucleotides that bind specific targets. They provide advantages over antibodies, including robustness, low cost, and reusability.
Jeddi, Iman, Saiz, Leonor
core   +2 more sources

Tracking Cryptosporidium parvum by Sequence Analysis of Small Double-Stranded RNA

Emerging Infectious Diseases, 2001
We sequenced a 173-nucleotide fragment of the small double-stranded viruslike RNA of Cryptosporidium parvum isolates from 23 calves and 38 humans. Sequence diversity was detected at 17 sites.
Lihua Xiao, Josef Limor, Caryn Bern, Altaf A. Lal   +3 more
doaj   +1 more source

A Low Sodium Diet Activates HSD2 Neurons in the Nucleus Tractus Solitarii to Promote Sodium Appetite Via the cAMP/MAPK Signaling Pathway

Journal of Integrative Neuroscience
Background: Sodium homeostasis is crucial for physiological balance, yet the neurobiological mechanisms underlying sodium appetite remain incompletely understood.
Xue Zhao, Yongqiang Chen, Ke Zhao, Yanxuan Wei, Yongan Zhang, Kun Liu, Luo Shi   +6 more
doaj   +1 more source

Expanding the repertoire of human tandem repeat RNA-binding proteins.

PLoS ONE, 2023
Protein regions consisting of arrays of tandem repeats are known to bind other molecular partners, including nucleic acid molecules. Although the interactions between repeat proteins and DNA are already widely explored, studies characterising tandem ...
Agustín Ormazábal, Matías Sebastián Carletti, Tadeo Enrique Saldaño, Martín Gonzalez Buitron, Julia Marchetti, Nicolas Palopoli, Alex Bateman   +6 more
doaj   +1 more source

PRADA: pipeline for RNA sequencing data analysis [PDF]

Bioinformatics, 2014
Abstract Summary:  Technological advances in high-throughput sequencing necessitate improved computational tools for processing and analyzing large-scale datasets in a systematic automated manner. For that purpose, we have developed PRADA (Pipeline for RNA-Sequencing Data Analysis), a flexible, modular and highly scalable software ...
Wandaliz, Torres-García, Siyuan, Zheng, Andrey, Sivachenko, Rahulsimham, Vegesna, Qianghu, Wang, Rong, Yao, Michael F, Berger, John N, Weinstein, Gad, Getz, Roel G W, Verhaak   +9 more
openaire   +2 more sources

Electroacupuncture Regulates Mitochondria-Endoplasmic Reticulum interactions via Fn1 in a Parkinson’s Disease Model: Transcriptomic Evidence

Journal of Integrative Neuroscience
Aims: Parkinson’s disease (PD) is characterized by dopaminergic neuron degeneration and disruption to mitochondria-associated endoplasmic reticulum membranes (MAMs).
Peilin Lyu, Feng Wen, Zhiyi Fu, Junying Li, Qiyan Li, Xiaowen Cai, Shengtao Huang, Xiaoke Qiu, Zhinan Zhang, Yong Huang, Jiping Zhang   +10 more
doaj   +1 more source

Probing of RNA structures in a positive sense RNA virus reveals selection pressures for structural elements. [PDF]

, 2017
In single stranded (+)-sense RNA viruses, RNA structural elements (SEs) play essential roles in the infection process from replication to encapsidation.
Aviran, Sharon, Choudhary, Krishna, Lucks, Julius B, Perry, Keith L, Thompson, Jeremy R, Watters, Kyle E   +5 more
core   +2 more sources

The First Complete Genome Sequence of a Novel Tetrastichus brontispae RNA Virus-1 (TbRV-1)

Viruses, 2019
The complete sequence of a novel RNA virus isolated from Tetrastichus brontispae (TbRV-1) was determined to be 12,239 nucleotides in length with five non-overlapping, linearly arranged coding sequences (CDS), potentially encoding nucleoproteins ...
E Meng, Baozhen Tang, Francisco Javier Sanchez-Garcia, Ting Qiao, Lang Fu, Yu Wang, You-Ming Hou, Jiang-Lin Wu, Zhi-Ming Chen   +8 more
doaj   +1 more source

Geometric combinatorics and computational molecular biology: branching polytopes for RNA sequences

, 2016
Questions in computational molecular biology generate various discrete optimization problems, such as DNA sequence alignment and RNA secondary structure prediction.
Drellich, Elizabeth, Gainer-Dewar, Andrew, Harrington, Heather A., He, Qijun, Heitsch, Christine, Poznanović, Svetlana   +5 more
core   +1 more source