Results 61 to 70 of about 1,743,892 (345)

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

FEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino, Meijie Li, Cécile Fizames, Mattia Adamo, Laurence Lejay, Christian Dubos, Matthieu Platre, Antoine Martin   +7 more
wiley   +1 more source

Paired-end small RNA sequencing reveals a possible overestimation in the isomiR sequence repertoire previously reported from conventional single read data analysis [PDF]

, 2021
José Francisco Sánchez-Herrero, Raquel Pluvinet, Antonio Luna De Haro, Lauro Sumoy   +3 more
openalex   +3 more sources

Protocol for identifying differentially expressed genes using the RumBall RNA-seq analysis platform

STAR Protocols
Summary: Here, we present a protocol for the identification of differentially expressed genes through RNA sequencing analysis. Starting with FASTQ files from public datasets, this protocol leverages RumBall within a self-contained Docker system.
Luis Augusto Eijy Nagai, Seohyun Lee, Ryuichiro Nakato   +2 more
doaj   +1 more source

A complex adaptive systems approach to the kinetic folding of RNA

, 2005
The kinetic folding of RNA sequences into secondary structures is modeled as a complex adaptive system, the components of which are possible RNA structural rearrangements (SRs) and their associated bases and base pairs. RNA bases and base pairs engage in
Abrahams, Baker, Cannone, Fisher, Flamm, Fontana, Freier, Gratias, Gultyaev, Hadany, Higgs, Hofacker, Isambert, Kauffman, Kauffman, Kawasaki, Lee, Levin, Mathews, Mathews, McCarthy, Metropolis, Mironov, Mochizuki, Morgan, Nagel, Ndifon, Poerschke, Poerschke, Schuster, Schuster, Schuster, Skellett, Tang, Vitreschack, Wilfred Ndifon, Woese, Wolfinger, Xayaphoummine, Yang, Zamora, Zhang   +41 more
core   +3 more sources

Power Analysis of Single Cell RNA-Sequencing Experiments [PDF]

Nature Methods, 2016
AbstractHigh-throughput single cell RNA sequencing (scRNA-seq) has become an established and powerful method to investigate transcriptomic cell-to-cell variation, and has revealed new cell types, and new insights into developmental process and stochasticity in gene expression.
Svensson, Valentine, Natarajan, Kedar Nath, Ly, Lam-Ha, Miragaia, Ricardo J, Labalette, Charlotte, Macaulay, Iain C, Cvejic, Ana, Teichmann, Sarah A   +7 more
openaire   +4 more sources

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

FEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

Hantavirus in African Wood Mouse, Guinea

Emerging Infectious Diseases, 2006
Hantaviruses are rodentborne, emerging viruses that cause life-threatening human diseases in Eurasia and the Americas. We detected hantavirus genome sequences in an African wood mouse (Hylomyscus simus) captured in Sangassou, Guinea.
Boris Klempa, Elisabeth Fichet-Calvet, Emilie Lecompte, Brita Auste, Vladimir Aniskin, Helga Meisel, Christiane Denys, Lamine Koivogui, Jan ter Meulen, Detlev H. Krüger   +9 more
doaj   +1 more source

DNApi: A De Novo Adapter Prediction Algorithm for Small RNA Sequencing Data. [PDF]

PLoS ONE, 2016
With the rapid accumulation of publicly available small RNA sequencing datasets, third-party meta-analysis across many datasets is becoming increasingly powerful.
Junko Tsuji, Zhiping Weng
doaj   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

A Systematic Bioinformatics Workflow With Meta-Analytics Identified Potential Pathogenic Factors of Alzheimer’s Disease

Frontiers in Neuroscience, 2020
Potential pathogenic factors, other than well-known APP, APOE4, and PSEN, can be further identified from transcriptomics studies of differentially expressed genes (DEGs) that are specific for Alzheimer’s disease (AD), but findings are often inconsistent ...
Sze Chung Yuen, Hongmei Zhu, Siu-wai Leung, Siu-wai Leung   +3 more
doaj   +1 more source