Results 51 to 60 of about 1,673,511 (373)

Mycoviruses as Triggers and Targets of RNA Silencing in White Mold Fungus Sclerotinia sclerotiorum

Viruses, 2018
This study aimed to demonstrate the existence of antiviral RNA silencing mechanisms in Sclerotinia sclerotiorum by infecting wild-type and RNA-silencing-deficient strains of the fungus with an RNA virus and a DNA virus.
Pauline K. Mochama, Prajakta Jadhav, Achal Neupane, Shin-Yi Lee Marzano   +3 more
semanticscholar   +1 more source

Molecular insights into the function of the viral RNA silencing suppressor HCPro.

The Plant Journal, 2016
Potyviral helper component proteinase (HCPro) is a well-characterized suppressor of antiviral RNA silencing, but its mechanism of action is not yet fully understood.
K. I. Ivanov, K. Eskelin, M. Bašić, Swarnalok De, Andres Lõhmus, M. Varjosalo, K. Mäkinen   +6 more
semanticscholar   +1 more source

Gene silencing in tick cell lines using small interfering or long double-stranded RNA [PDF]

, 2012
Gene silencing by RNA interference (RNAi) is an important research tool in many areas of biology. To effectively harness the power of this technique in order to explore tick functional genomics and tick-microorganism interactions, optimised parameters ...
A-C Barnard, AA Latif, AE Lew-Tabor, Alain Kohl, AM Nijhof, AM Nijhof, CL Donald, DE Brackney, EF Blouin, EM Morazzani, Esther Schnettler, F Jongejan, G Attarzadeh-Yazdi, G Barry, Gerald Barry, GJ Hannon, I Sifuentes-Romero, J Fuente de la, J Fuente de la, J Fuente de la, J Fuente de la, J Fuente de la, JC Clemens, JC Scott, JE George, JH Pedra, John K. Fazakerley, K Kiiver, KM Kocan, L Bell-Sakyi, L Bell-Sakyi, L Bell-Sakyi, L Bell-Sakyi, L Song, Lesley Bell-Sakyi, MGR Varma, P Liljestrom, P Lingor, P Willadsen, Pilar Alberdi, R Fragkoudis, R Fragkoudis, RA Zambon, S Bivalkar-Mehla, S Garcia, S Garcia, S Kurscheid, S Narasimhan, Sabine Weisheit, SM Hammond, SW Ding, TJ Kurtti, TJ Kurtti, UG Munderloh, V Nene, V Shkap, Z Zivkovic, Z Zivkovic   +57 more
core   +4 more sources

Distinct Effects of p19 RNA Silencing Suppressor on Small RNA Mediated Pathways in Plants

PLoS Pathogens, 2016
RNA silencing is one of the main defense mechanisms employed by plants to fight viruses. In change, viruses have evolved silencing suppressor proteins to neutralize antiviral silencing.
Levente Kontra, Tibor Csorba, M. Tavazza, A. Lucioli, R. Tavazza, Simon Moxon, V. Tisza, A. Medzihradszky, M. Turina, J. Burgyán   +9 more
semanticscholar   +1 more source

Effects of the Crinivirus Coat Protein–Interacting Plant Protein SAHH on Post-Transcriptional RNA Silencing and Its Suppression

Molecular Plant-Microbe Interactions, 2013
In plants, post-transcriptional gene silencing (PTGS) is a sequence-specific mechanism of RNA degradation induced by double-stranded RNA (dsRNA), which is processed into small interfering RNAs (siRNAs).
M. Carmen Cañizares, Rosa Lozano-Durán, Tomás Canto, Eduardo R. Bejarano, David M. Bisaro, Jesús Navas-Castillo, Enrique Moriones   +6 more
doaj   +1 more source

An enhanced CRISPR repressor for targeted mammalian gene regulation. [PDF]

, 2018
The RNA-guided endonuclease Cas9 can be converted into a programmable transcriptional repressor, but inefficiencies in target-gene silencing have limited its utility.
Cecchi, Ryan J, Chan, Yingleong, Chavez, Alejandro, Church, George M, Church, George M, Collins, James J, Davidsohn, Noah, Ebrahimkhani, Mo R, Guo, Xiaoge, Kiani, Samira, Kuo, Chih-Chung, Lance-Byrne, Alissa, Lewis, Nathan E, Lim, Elaine T, Menn, David, Milanova, Denitsa, Pradhan, Swechchha, Sharma, Sumana, Tung, Angela, Tuttle, Marcelle, Yeo, Nan Cher   +20 more
core   +1 more source

Silencing viruses by RNA interference

Microbes and Infection, 2005
Post-transcriptional gene silencing (PTGS) makes possible new approaches for studying the various steps of the viral cycle. Plus-strand RNA viruses appear to be attractive targets for small interfering RNAs (siRNAs), as their genome functions as both mRNA and replication template. PTGS creates an alternative to classic reverse genetics for viruses with
Colbère-Garapin, Florence, Blondel, Bruno, Saulnier, Aure, Pelletier, Isabelle, Labadie, Karine   +4 more
openaire   +4 more sources

Identification of Silencing Suppressor Protein Encoded by Strawberry Mottle Virus

Frontiers in Plant Science, 2022
Strawberry mottle virus (SMoV) is associated with strawberry decline disease, causing losses to fruit yield and quality. In this study, using a screening system that enables detection of both local and systemic plant host (RNA silencing) defense ...
Lingjiao Fan, Chengyong He, Dehang Gao, Tengfei Xu, Fei Xing, Jiaqi Yan, Binhui Zhan, Shifang Li, Hongqing Wang   +8 more
doaj   +1 more source

Sense- and antisense-mediated resistance against Sri Lankan cassava mosaic virus (SLCMV) in Nicotiana benthamiana

Biologia Plantarum, 2019
Sri Lankan cassava mosaic virus (SLCMV) is the principal causal agent of cassava mosaic disease in the Indian subcontinent. To gain resistance against the virus, the coat protein (CP) gene, namely the AV1 of SLCMV-Adivaram isolate, was cloned in either ...
A. GOGOI, A. KALDIS, I. DASGUPTA, B.K. BORAH, A. VOLOUDAKIS   +4 more
doaj   +1 more source

Reprogramming of RNA silencing triggered by cucumber mosaic virus infection in Arabidopsis

Genome Biology, 2021
Background RNA silencing has an important role mediating sequence-specific virus resistance in plants. The complex interaction of viruses with RNA silencing involves the loading of viral small interfering RNAs (vsiRNAs) into its host ARGONAUTE (AGO ...
Maria Luz Annacondia, German Martinez
doaj   +1 more source