Results 61 to 70 of about 365,878 (302)
Biologia Plantarum, 2019 Sri Lankan cassava mosaic virus (SLCMV) is the principal causal agent of cassava mosaic disease in the Indian subcontinent. To gain resistance against the virus, the coat protein (CP) gene, namely the AV1 of SLCMV-Adivaram isolate, was cloned in either ...
A. GOGOI +4 more
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The type II poly(A)-binding protein PABP-2 is a downstream target of the "let-7" microRNA in the heterochronic pathway of "Caenorhabditis elegans" : mechanisms of microRNA-mediated gene silencing in "Caenorhabditis elegans" [PDF]
, 2012 microRNAs (miRNAs) are a large class of small, non-coding RNAs that post-transcriptionally regulate gene expression in animals, plants and protozoa. miRNAs are genomically encoded and transcribed by RNA polymerase II. Primary transcripts are sequentially
Hurschler, Benjamin
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Viral suppression of RNA silencing [PDF]
Science China Life Sciences, 2012 يلعب إسكات الجينات (إسكات الحمض النووي الريبي) دورًا أساسيًا في الدفاع المضاد للفيروسات في النباتات والفطريات واللافقاريات. تقوم الفيروسات بتشفير البروتينات التي تمنع إسكات الجينات لمواجهة دفاع المضيف. تم تحديد المثبطات الفيروسية لإسكات الحمض النووي الريبي (RSVs) من جميع الفيروسات النباتية تقريبًا التي تولد وبعض فيروسات الحشرات والثدييات. كشفت الدراسات
Lin Jiang, Chunhong Wei, Yang Li
openaire +2 more sources
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
SiRNA Mediated Gene Silencing: A Mini Review
Aceh International Journal of Science and Technology, 2012 - RNA interference (RNAi) technology has become a novel tool for silencing gene expression in cells or organisms. RNA interference is the process that double-stranded RNA induces the homology-dependent degradation of cognate mRNA mediated by 21-23 ...
Baby Joseph, Ajisha S.U, Jeevitha M.V
doaj +3 more sources
, 2010 We report that combining a DNA analog (2?F-ANA) with rigid RNA analogs [2?F-RNA and/or locked nucleic acid (LNA)] in siRNA duplexes can produce gene silencing agents with enhanced potency. The favored conformations of these two analogs are different, and
Alain, Tommy +9 more
core +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Viruses, 2018 Plant viruses are inducers and targets of antiviral RNA silencing. To condition susceptibility, most plant viruses encode silencing suppressor proteins that interfere with antiviral RNA silencing.
Hernan Garcia-Ruiz +2 more
doaj +1 more source
A Novel Epigenetic Silencing Pathway Involving the Highly Conserved 5'-3' Exoribonuclease Dhp1/Rat1/Xrn2 in Schizosaccharomyces pombe. [PDF]
PLoS Genetics, 2016 Epigenetic gene silencing plays a critical role in regulating gene expression and contributes to organismal development and cell fate acquisition in eukaryotes.
James Franklin Tucker +6 more
doaj +1 more source
Systemic RNAi mediated gene silencing in the anhydrobiotic nematode Panagrolaimus superbus [PDF]
, 2008 Background: Gene silencing by RNA interference (RNAi) is a powerful tool for functional genomics. Although RNAi was first described in Caenorhabditis elegans, several nematode species are unable to mount an RNAi response when exposed to exogenous double ...
Jacqueline Boyd +9 more
core +1 more source