Results 21 to 30 of about 106,855 (258)

Viral suppressors: Combatting RNA silencing [PDF]

Nature Plants, 2017
[EN] Plants defend themselves from invading viruses using RNA silencing. However, plant viruses try to spoil this defensive mechanism by expressing one or more proteins that act as RNA silencing suppressors. One such protein spoils plant defence by transporting the silencing signal into the peroxisomes to avoid its systemic spread.
openaire   +4 more sources

Identification of the Potential Virulence Factors and RNA Silencing Suppressors of Mulberry Mosaic Dwarf-Associated Geminivirus

Viruses, 2018
Plant viruses encode virulence factors or RNA silencing suppressors to reprogram plant cellular processes or to fine-tune host RNA silencing-mediated defense responses.
Xiuling Yang, Yanxiang Ren, Shaoshuang Sun, Dongxue Wang, Fanfan Zhang, Dawei Li, Shifang Li, Xueping Zhou   +7 more
doaj   +1 more source

Naturally occurring substitution of an amino acid in a plant virus gene-silencing suppressor enhances viral adaptation to increasing thermal stress.

PLoS Pathogens, 2023
Cereal yellow dwarf virus (CYDV-RPV) encodes a P0 protein that functions as a viral suppressor of RNA silencing (VSR). The strength of silencing suppression is highly variable among CYDV-RPV isolates. In this study, comparison of the P0 sequences of CYDV-
Lina Cai, Mingqing Dang, Yawen Yang, Ruoxin Mei, Fan Li, Xiaorong Tao, Peter Palukaitis, Randy Beckett, W Allen Miller, Stewart M Gray, Yi Xu   +10 more
doaj   +1 more source

Bacterial pathogens encode suppressors of RNA-mediated silencing [PDF]

Genome Biology, 2008
Plant pathogenic bacteria encounter host defenses mediated by a variety of small RNAs. Bacterial suppressors of silencing that inhibit multiple steps of plant microRNA biogenesis and function have recently been identified.
Mosher, Rebecca A, Baulcombe, David C
openaire   +2 more sources

A calmodulin-like protein suppresses RNA silencing and promotes geminivirus infection by degrading SGS3 via the autophagy pathway in Nicotiana benthamiana.

PLoS Pathogens, 2017
A recently characterized calmodulin-like protein is an endogenous RNA silencing suppressor that suppresses sense-RNA induced post-transcriptional gene silencing (S-PTGS) and enhances virus infection, but the mechanism underlying calmodulin-like protein ...
Fangfang Li, Nan Zhao, Zhenghe Li, Xiongbiao Xu, Yaqin Wang, Xiuling Yang, Shu-Sheng Liu, Aiming Wang, Xueping Zhou   +8 more
doaj   +1 more source

Silencing of a viral RNA silencing suppressor in transgenic plants

Journal of General Virology, 2002
High expression levels of the helper component proteinase (HCpro), a known virus suppressor of RNA silencing, were attained in Nicotiana benthamiana transformed with the HCpro cistron of Potato virus A (PVA, genus Potyvirus). No spontaneous silencing of the HCpro transgene was observed, in contrast to the PVA coat protein (CP)-encoding transgene in ...
Eugene I, Savenkov, Jari P T, Valkonen
openaire   +2 more sources

The Heterologous Expression of the p22 RNA Silencing Suppressor of the Crinivirus Tomato Chlorosis Virus from Tobacco Rattle Virus and Potato Virus X Enhances Disease Severity but Does Not Complement Suppressor-Defective Mutant Viruses

Viruses, 2017
To counteract host antiviral RNA silencing, plant viruses express suppressor proteins that function as pathogenicity enhancers. The genome of the Tomato chlorosis virus (ToCV) (genus Crinivirus, family Closteroviridae) encodes an RNA silencing suppressor,
Yazmín Landeo-Ríos, Jesús Navas-Castillo, Enrique Moriones, M. Carmen Cañizares   +3 more
doaj   +1 more source

Multiple Domains of the Tobacco mosaic virus p126 Protein Can Independently Suppress Local and Systemic RNA Silencing

Molecular Plant-Microbe Interactions, 2012
Small RNA-mediated RNA silencing is a widespread antiviral mechanism in plants and other organisms. Many viruses encode suppressors of RNA silencing for counter-defense.
Li-Ya Wang, Shih-Shun Lin, Ting-Hsuan Hung, Tsai-Kun Li, Nai-Chun Lin, Tang-Long Shen   +5 more
doaj   +1 more source

Size Selective Recognition of siRNA by an RNA Silencing Suppressor [PDF]

Cell, 2003
RNA silencing in plants likely exists as a defense mechanism against molecular parasites such as RNA viruses, retrotransposons, and transgenes. As a result, many plant viruses have adapted mechanisms to evade and suppress gene silencing. Tombusviruses express a 19 kDa protein (p19), which has been shown to suppress RNA silencing in vivo and bind ...
Vargason, Jeff, Szittya, Gyorgy, Burgyan, Jozsef, Tanaka Hall, Traci M.   +3 more
openaire   +2 more sources

Grapevine Fanleaf Virus RNA1-Encoded Proteins 1A and 1BHel Suppress RNA Silencing

Molecular Plant-Microbe Interactions, 2023
Grapevine fanleaf virus (GFLV) (genus Nepovirus, family Secoviridae) causes fanleaf degeneration, one of the most damaging viral diseases of grapevines. Despite substantial advances at deciphering GFLV-host interactions, how this virus overcomes the host
Jiyeong Choi, Samira Pakbaz, Luz Marcela Yepes, Elizabeth Jeannette Cieniewicz, Corinne Schmitt-Keichinger, Rossella Labarile, Serena Anna Minutillo, Michelle Heck, Jian Hua, Marc Fuchs   +9 more
doaj   +1 more source