Results 31 to 40 of about 106,855 (258)

Identification of an RNA silencing suppressor encoded by a mastrevirus

Journal of General Virology, 2014
Wheat dwarf virus (WDV) is a DNA virus belonging to the genus Mastrevirus of the family Geminiviridae. In this study, we report that the Rep protein encoded by WDV is a RNA silencing supressor as determined by co-infiltration assays using transgenic Nicotiana benthamiana line 16c carrying the GFP reporter gene. The Rep protein was shown to inhibit both
Yaqin, Wang, Mingqing, Dang, Huwei, Hou, Yuzhen, Mei, Yajuan, Qian, Xueping, Zhou   +5 more
openaire   +2 more sources

Aspergillus Mycoviruses Are Targets and Suppressors of RNA Silencing [PDF]

Eukaryotic Cell, 2008
ABSTRACT RNA silencing can function as a virus defense mechanism in a diverse range of eukaryotes, and many viruses are capable of suppressing the silencing machinery targeting them. However, the extent to which this occurs between fungal RNA silencing and mycoviruses is unclear.
T M, Hammond, M D, Andrewski, M J, Roossinck, N P, Keller   +3 more
openaire   +2 more sources

Acquisition of full-length viral helicase domains by insect retrotransposon-encoded polypeptides

Frontiers in Microbiology, 2015
Recent metagenomic studies in insects identified many sequences unexpectedly closely related to plant virus genes. Here we describe a new example of this kind, insect R1 LINEs with an additional C-terminal domain in their open reading frame 2.
Ekaterina eLazareva, Alexander eLezzhov, Nikita eVassetzky, Andrey G. Solovyev, Sergey eMorozov   +4 more
doaj   +1 more source

The Ebola Virus VP35 Protein Is a Suppressor of RNA Silencing

PLoS Pathogens, 2007
RNA silencing or interference (RNAi) is a gene regulation mechanism in eukaryotes that controls cell differentiation and developmental processes via expression of microRNAs. RNAi also serves as an innate antiviral defence response in plants, nematodes, and insects.
Haasnoot, J., de Vries, W., Geutjes, E.J., Prins, M.W., de Haan, P., Berkhout, B.   +5 more
openaire   +4 more sources

Mosquito-Borne Viruses and Suppressors of Invertebrate Antiviral RNA Silencing [PDF]

Viruses, 2014
The natural maintenance cycles of many mosquito-borne viruses require establishment of persistent non-lethal infections in the invertebrate host. While the mechanisms by which this occurs are not well understood, antiviral responses directed by small RNAs are important in modulating the pathogenesis of viral infections in disease vector mosquitoes.
O'Neal, Scott T., Samuel, Glady Hazitha, Adelman, Zach N., Myles, Kevin M.   +3 more
openaire   +4 more sources

Olive Mild Mosaic Virus Coat Protein and P6 Are Suppressors of RNA Silencing, and Their Silencing Confers Resistance against OMMV

Viruses, 2018
RNA silencing is an important defense mechanism in plants, yet several plant viruses encode proteins that suppress this mechanism. In this study, the genome of the Olive mild mosaic virus (OMMV) was screened for silencing suppressors.
Carla MR Varanda, Patrick Materatski, Maria Doroteia Campos, Maria Ivone E. Clara, Gustavo Nolasco, Maria do Rosário Félix   +5 more
doaj   +1 more source

Identification of an RNA-silencing suppressor in the genome of Grapevine virus A

Journal of General Virology, 2006
Higher plants use post-transcriptional gene silencing (PTGS), an RNA-degradation system, as a defence mechanism against viral infections. To counteract this, plant viruses encode and express PTGS suppressor proteins. Four of the five proteins encoded by the Grapevine virus A (GVA) genome were screened using a green fluorescent protein (GFP)-based ...
ZHOU ZSH, DELL'ORCO M, SALDARELLI P, TURTURO C, MINAFRA A, MARTELLI GP   +5 more
openaire   +3 more sources

The Luteovirus P4 Movement Protein Is a Suppressor of Systemic RNA Silencing [PDF]

Viruses, 2017
The plant viral family Luteoviridae is divided into three genera: Luteovirus, Polerovirus and Enamovirus. Without assistance from another virus, members of the family are confined to the cells of the host plant’s vascular system. The first open reading frame (ORF) of poleroviruses and enamoviruses encodes P0 proteins which act as silencing suppressor ...
Fusaro, Adriana, Barton, Deborah, Nakasugi, Kenlee, Jackson, Craig, Kalischuk, Melanie, Kawchuk, Lawrence, Vaslin, Maite, Correa, Regis, Waterhouse, Peter   +8 more
openaire   +5 more sources

Cucurbit Chlorotic Yellows Virus p22 Protein Interacts with Cucumber SKP1LB1 and Its F-Box-Like Motif Is Crucial for Silencing Suppressor Activity

Viruses, 2019
Plants use RNA silencing as a defense against viruses. In response, viruses encode various RNA silencing suppressors to counteract the antiviral silencing.
Siyu Chen, Xinyan Sun, Yajuan Shi, Ying Wei, Xiaoyu Han, Honglian Li, Linlin Chen, Bingjian Sun, Hangjun Sun, Yan Shi   +9 more
doaj   +1 more source

Identification of Silencing Suppressor Protein Encoded by Strawberry Mottle Virus

Frontiers in Plant Science, 2022
Strawberry mottle virus (SMoV) is associated with strawberry decline disease, causing losses to fruit yield and quality. In this study, using a screening system that enables detection of both local and systemic plant host (RNA silencing) defense ...
Lingjiao Fan, Chengyong He, Dehang Gao, Tengfei Xu, Fei Xing, Jiaqi Yan, Binhui Zhan, Shifang Li, Hongqing Wang   +8 more
doaj   +1 more source