Riboswitch control of bacterial RNA stability. [PDF]
Mol Microbiol, 2021 AbstractAlthough riboswitches have long been known to regulate translation initiation and transcription termination, a growing body of evidence indicates that they can also control bacterial RNA lifetimes by acting directly to hasten or impede RNA degradation. Ligand binding to the aptamer domain of a riboswitch can accelerate RNA decay by triggering a
Richards J, Belasco JG.
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RNA Stability Measurements Using RT-qPCR in Arabidopsis Seedlings [PDF]
Bio-Protocol, 2020 Steady-state mRNA levels are determined by both the rates of transcription and degradation. Regulation of mRNA stability and/or degradation are key factors that can significantly affect mRNA levels and its biological functions.
Tianran Jia, Brandon Le
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RNA stability controlled by m6A methylation contributes to X-to-autosome dosage compensation in mammals. [PDF]
Nat Struct Mol Biol, 2023 Rücklé C +16 more
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Role of the 5' end phosphorylation state for small RNA stability and target RNA regulation in bacteria. [PDF]
Nucleic Acids Res, 2023 Schilder A, Görke B.
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Analysis of SARS-CoV-2 RNA Stability and Infectivity in Oropharyngeal Swab Samples [PDF]
, 2021 Neumann M +4 more
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Post-mortem Interval and Its Relation with the RNA Degradation in the Dental Pulp in Submerged Teeth
Arab Journal of Forensic Sciences & Forensic Medicine, 2021 Post-mortem interval is the time between death and the discovery of the body or human remains. Teeth are the most resistant structures of the human body, able to withstand extreme conditions such as high temperature, humidity, and post-mortem degradation.
Bruna S. Borges +3 more
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Incoherent dual regulation by a SAM-II riboswitch controlling translation at a distance
RNA Biology, 2022 In Sinorhizobium meliloti, the methionine biosynthesis genes metA and metZ are preceded by S-adenosyl-L-methionine (SAM) riboswitches of the SAM-II class. Upon SAM binding, structural changes in the metZ riboswitch were predicted to cause transcriptional
Robina Scheuer +5 more
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Arginine multivalency stabilizes protein/RNA condensates [PDF]
Protein Science, 2021 Abstract Biomolecular condensates assembled through liquid–liquid phase separation (LLPS) of proteins and RNAs are currently recognized to play an important role in cellular organization. Their assembly depends on the formation of a network of transient, multivalent interactions between flexible scaffold biomolecules.
Matteo Paloni +2 more
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Characterizing RNA stability genome-wide through combined analysis of PRO-seq and RNA-seq data
BMC Biology, 2021 Background The concentrations of distinct types of RNA in cells result from a dynamic equilibrium between RNA synthesis and decay. Despite the critical importance of RNA decay rates, current approaches for measuring them are generally labor-intensive ...
Amit Blumberg +8 more
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Predicting 3D structure and stability of RNA pseudoknots in monovalent and divalent ion solutions. [PDF]
PLoS Computational Biology, 2018 RNA pseudoknots are a kind of minimal RNA tertiary structural motifs, and their three-dimensional (3D) structures and stability play essential roles in a variety of biological functions.
Ya-Zhou Shi +4 more
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