Regulation of RNA stability at the 3' end. [PDF]
Biol Chem, 2021 Abstract RNA homeostasis is regulated by a multitude of cellular pathways. Although the addition of untemplated adenine residues to the 3′ end of mRNAs has long been known to affect RNA stability, newly developed techniques for 3′-end sequencing of RNAs have revealed various unexpected RNA modifications.
Frederick MI, Heinemann IU.
europepmc +4 more sources
Low RNA stability signifies strong expression regulatability of tumor suppressors [PDF]
Nucleic Acids Research, 2023 Xinlei Gao, Yanqiang Li, Qi Cao
exaly +2 more sources
Post-mortem Interval and Its Relation with the RNA Degradation in the Dental Pulp in Submerged Teeth
Arab Journal of Forensic Sciences & Forensic Medicine, 2021 Post-mortem interval is the time between death and the discovery of the body or human remains. Teeth are the most resistant structures of the human body, able to withstand extreme conditions such as high temperature, humidity, and post-mortem degradation.
Bruna S. Borges +3 more
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Incoherent dual regulation by a SAM-II riboswitch controlling translation at a distance
RNA Biology, 2022 In Sinorhizobium meliloti, the methionine biosynthesis genes metA and metZ are preceded by S-adenosyl-L-methionine (SAM) riboswitches of the SAM-II class. Upon SAM binding, structural changes in the metZ riboswitch were predicted to cause transcriptional
Robina Scheuer +5 more
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VfoldCPX Server: Predicting RNA-RNA Complex Structure and Stability. [PDF]
PLoS ONE, 2016 RNA-RNA interactions are essential for genomic RNA dimerization, mRNA splicing, and many RNA-related gene expression and regulation processes. The prediction of the structure and folding stability of RNA-RNA complexes is a problem of significant ...
Xiaojun Xu, Shi-Jie Chen
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Stability of RNA Molecules Stored in GITC
BioTechniques, 1998 Rebecca C. Gilleland, Richard D. Hockett
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Characterizing RNA stability genome-wide through combined analysis of PRO-seq and RNA-seq data
BMC Biology, 2021 Background The concentrations of distinct types of RNA in cells result from a dynamic equilibrium between RNA synthesis and decay. Despite the critical importance of RNA decay rates, current approaches for measuring them are generally labor-intensive ...
Amit Blumberg +8 more
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Repression of PUM1-mediated mRNA decay activates translesion synthesis after DNA damage
Molecular & Cellular Oncology, 2020 Biological roles of Pumilio1 (PUM1) in ubiquitous cells remain unclear. Here we identify 48 degrading target mRNAs by combined analysis of transcriptome-wide mRNA stabilities and the binding of mRNAs.
Toshimichi Yamada +2 more
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Stability of SARS-CoV-2 RNA in Nonsupplemented Saliva
Emerging Infectious Diseases, 2021 The expense of saliva collection devices designed to stabilize severe acute respiratory syndrome coronavirus 2 RNA is prohibitive to mass testing. However, virus RNA in nonsupplemented saliva is stable for extended periods and at elevated temperatures ...
Isabel M. Ott +23 more
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Frozen section histopathology and preanalytical factors affecting nucleic acid integrity in biobanked fresh-frozen human cancer tissues [PDF]
Journal of Pathology and Translational MedicineBackground In this study, we evaluated the effects of storage duration and ischemic time on nucleic acid quality of fresh-frozen tissue (FFT) from colon adenocarcinoma (COAD), hepatocellular carcinoma (HCC), and renal cell carcinoma (RCC) collected at ...
Soungeun Kim +4 more
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