Results 101 to 110 of about 1,640,958 (330)

Special Issue: Frontiers in RNA Structure

Molecules, 2020
The frontiers of our knowledge about RNA structure are rapidly moving [...]
Quentin Vicens
doaj   +1 more source

A model for the study of ligand binding to the ribosomal RNA helix h44. [PDF]

, 2010
Oligonucleotide models of ribosomal RNA domains are powerful tools to study the binding and molecular recognition of antibiotics that interfere with bacterial translation.
Dibrov, Sergey M, Hermann, Thomas, Parsons, Jerod   +2 more
core   +3 more sources

Structure-Guided Engineering of the Homodimeric Mango-IV Fluorescence Turn-on Aptamer Yields an RNA FRET Pair [PDF]

, 2020
Robert J. Trachman, Razvan Cojocaru, Di Wu, Grzegorz Piszczek, Michaël Ryckelynck, Peter J. Unrau, A.R. Ferré-D′Amaré   +6 more
openalex   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Genome organization and interaction with capsid protein in a multipartite RNA virus. [PDF]

, 2020
We report the asymmetric reconstruction of the single-stranded RNA (ssRNA) content in one of the three otherwise identical virions of a multipartite RNA virus, brome mosaic virus (BMV).
Beren, Christian, Chakravarty, Antara, Cui, Yanxiang, Gelbart, William M, Knobler, Charles M, Rao, ALN, Yang, Xue, Zhou, Z Hong   +7 more
core  

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

HiPR: High-throughput probabilistic RNA structure inference

Computational and Structural Biotechnology Journal, 2020
Recent high-throughput structure-sensitive genome-wide sequencing-based assays have enabled large-scale studies of RNA structure, and robust transcriptome-wide computational prediction of individual RNA structures across RNA classes from these assays has
Pavel P. Kuksa, Fan Li, Sampath Kannan, Brian D. Gregory, Yuk Yee Leung, Li-San Wang   +5 more
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Watson-Crick pairing, the Heisenberg group and Milnor invariants

, 2008
We study the secondary structure of RNA determined by Watson-Crick pairing without pseudo-knots using Milnor invariants of links. We focus on the first non-trivial invariant, which we call the Heisenberg invariant.
Gadgil, Siddhartha
core   +1 more source

ASPRAlign: a tool for the alignment of RNA secondary structures with arbitrary pseudoknots [PDF]

, 2020
Michela Quadrini, Luca Tesei, Emanuela Merelli   +2 more
openalex   +1 more source