Results 71 to 80 of about 1,301,283 (332)
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
Computational and Structural Biotechnology Journal, 2022 RNA secondary structures can carry out essential cellular functions alone or interact with one another to form the hierarchical tertiary structures.
Tzu-Hsien Yang +3 more
doaj
Structure and RNA content of the prosomes
FEBS Letters, 1992 Duck erythroblast, prosomes were analysed by small angle neutron scattering (SANS), dynamic light scattering and (cryo‐)electron microscopy. A molecular weight of ≈ 720,000 ± 50,000, a radius of gyration of 64 ± 2 Å and a hydrodynamic radius of ≈ 86 Å were obtained.
Wilma Bergsma-Schutter +7 more
openaire +4 more sources
Shapes of topological RNA structures [PDF]
Mathematical Biosciences, 2015 27 pages, 11 figures, 2 tables.
Christian M. Reidys, Fenix W. D. Huang
openaire +4 more sources
Identification of novel small molecule inhibitors of ETS transcription factors
FEBS Letters, EarlyView.ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla +9 more
wiley +1 more source
Fatgraph models of RNA structure
Computational and Mathematical Biophysics, 2017 In this review paper we discuss fatgraphs as a conceptual framework for RNA structures. We discuss various notions of coarse-grained RNA structures and relate them to fatgraphs.We motivate and discuss the main intuition behind the fatgraph model and ...
Huang Fenix +2 more
doaj +1 more source
RNA Dependent RNA Polymerases: Insights from Structure, Function and Evolution
Viruses, 2018 RNA dependent RNA polymerase (RdRp) is one of the most versatile enzymes of RNA viruses that is indispensable for replicating the genome as well as for carrying out transcription.
Sangita Venkataraman +2 more
doaj +1 more source
Characteristics of equipartition for RNA structure [PDF]
BMC Proceedings, 2014 With the continuous discovery of novel RNA molecules with key cellular functions and of novel pathways and interaction networks, the need for structural information of RNA is still increasing. In order to predict structure of long RNA and understand its natural folding mechanism, exploring the characteristic of RNA structure is an important issue.The ...
Daming Zhu +5 more
openaire +3 more sources
Social context prevents heat hormetic effects against mutagens during fish development
FEBS Letters, EarlyView.This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere +5 more
wiley +1 more source
Structural mechanisms for binding and activation of a contact-quenched fluorophore by RhoBAST
Nature CommunicationsThe fluorescent light-up aptamer RhoBAST, which binds and activates the fluorophore–quencher conjugate tetramethylrhodamine-dinitroaniline with high affinity, super high brightness, remarkable photostability, and fast exchange kinetics, exhibits ...
Yufan Zhang +6 more
doaj +1 more source