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Hidden Viral Sequences in Public Sequencing Data and Warning for Future Emerging Diseases
mBio, 2021 RNA viruses cause numerous emerging diseases, mostly due to transmission from mammalian and avian reservoirs. Large-scale surveillance of RNA viral infections in these animals is a fundamental step for controlling viral infectious diseases.
Junna Kawasaki +3 more
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SARS-CoV-2: from its discovery to genome structure, transcription, and replication
Cell & Bioscience, 2021 SARS-CoV-2 is an extremely contagious respiratory virus causing adult atypical pneumonia COVID-19 with severe acute respiratory syndrome (SARS). SARS-CoV-2 has a single-stranded, positive-sense RNA (+RNA) genome of ~ 29.9 kb and exhibits significant ...
Ayslan Castro Brant +4 more
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Cloned defective interfering influenza virus protects ferrets from pandemic 2009 influenza A virus and allows protective immunity to be established [PDF]
, 2012 Influenza A viruses are a major cause of morbidity and mortality in the human population, causing epidemics in the winter, and occasional worldwide pandemics.
Carroll, Miles W. +9 more
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Reverse Genetics and Artificial Replication Systems of Borna Disease Virus 1
Viruses, 2022 Borna disease virus 1 (BoDV-1) is a neurotropic RNA virus belonging to the family Bornaviridae within the order Mononegavirales. Whereas BoDV-1 causes neurological and behavioral disorders, called Borna disease (BD), in a wide range of mammals, its ...
Takehiro Kanda, Keizo Tomonaga
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Nucleic Acids Research, 2008 The RNA Virus Database is a database and web application describing the genome organization and providing analytical tools for the 938 known species of RNA virus. It can identify submitted nucleotide sequences, can place them into multiple whole-genome alignments (in species where more than one isolate has been fully sequenced) and contains translated ...
Belshaw, Robert +3 more
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Human Papillomavirus Type 16 Circular RNA Is Barely Detectable for the Claimed Biological Activity
mBio, 2022 Human papillomavirus type 16 (HPV16) E7 oncoprotein plays an essential role in cervical carcinogenesis and is encoded predominantly by an E6*I mRNA through alternative RNA splicing of a P97 promoter-transcribed bicistronic E6E7 pre-mRNA.
Lulu Yu, Zhi-Ming Zheng
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Scientific Reports, 2020 RNA virus-based episomal vector (REVec) is an emerging viral vector system that mediates long-term stable gene expression in variety of cell types in vitro.
Yumiko Komatsu +3 more
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Multifaceted contributions of Dicer2 to arbovirus transmission by Aedes aegypti
Cell Reports, 2023 Summary: Arthropod-borne viruses (arboviruses) transmitted by Aedes aegypti mosquitoes are an increasing threat to global health. The small interfering RNA (siRNA) pathway is considered the main antiviral immune pathway of insects, but its effective ...
Sarah Hélène Merkling +11 more
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Comparison of 6/94 Virus and Sendai Virus RNA by RNA-RNA Hybridization [PDF]
Journal of Virology, 1974 The genomic RNA of 6/94 virus, an agent isolated from the brains of multiple sclerosis patients, was studied for sequence homology by RNA-RNA hybridization with closely related Sendai virus and another paramyxovirus virus, Newcastle disease virus.
D, Kolakofsky, P F, Spahr, H, Koprowski
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Virology Journal, 2017 Background Borna disease virus (BoDV), which has a negative-sense, single-stranded RNA genome, causes persistent infection in the cell nucleus. The nuclear export signal (NES) of the viral nucleoprotein (N) consisting of leucine at positions 128 and 131 ...
Mako Yanai +3 more
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