Results 1 to 10 of about 3,158,683 (345)

Metavirome of 31 tick species provides a compendium of 1,801 RNA virus genomes

Nature Microbiology, 2023
The metavirome of 31 tick species sheds light on the diversity and distinct evolution of tick-associated RNA viruses, and lays the foundation for better understanding of tick–virus interaction. The increasing prevalence and expanding distribution of tick-
Xue-bing Ni, Xiao-ming Cui, Jinyuan Liu, Run-Ze Ye, Yu-Qian Wu, Jia-Fu Jiang, Yi Sun, Qian Wang, M. H. Shum, Q. Chang, Lin Zhao, Xiao-Hu Han, Ke Ma, Shi-Jing Shen, Ming-Zhu Zhang, Wen-Bin Guo, Jinxin Zhu, L. Zhan, Liang-Jing Li, S. Ding, D. Zhu, Jie Zhang, Luoyuan Xia, X. Oong, X. Ruan, Hong Shao, Teng-Cheng Que, Guang-yuan Liu, C. Du, En-jiong Huang, Xin Wang, Liuyun Du, Chongcai Wang, Wenqiang Shi, Yu-Sheng Pan, Yuhao Zhou, J. Qu, Jiang Ma, Cai-Wei Gong, Qibin Chen, Qian Qin, T. Lam, Na Jia, Wu-Chun Cao   +43 more
semanticscholar   +1 more source

Hidden Viral Sequences in Public Sequencing Data and Warning for Future Emerging Diseases

mBio, 2021
RNA viruses cause numerous emerging diseases, mostly due to transmission from mammalian and avian reservoirs. Large-scale surveillance of RNA viral infections in these animals is a fundamental step for controlling viral infectious diseases.
Junna Kawasaki, Shohei Kojima, Keizo Tomonaga, Masayuki Horie   +3 more
doaj   +1 more source

SARS-CoV-2: from its discovery to genome structure, transcription, and replication

Cell & Bioscience, 2021
SARS-CoV-2 is an extremely contagious respiratory virus causing adult atypical pneumonia COVID-19 with severe acute respiratory syndrome (SARS). SARS-CoV-2 has a single-stranded, positive-sense RNA (+RNA) genome of ~ 29.9 kb and exhibits significant ...
Ayslan Castro Brant, Wei Tian, Vladimir Majerciak, Wei Yang, Zhi-Ming Zheng   +4 more
doaj   +1 more source

Reverse Genetics and Artificial Replication Systems of Borna Disease Virus 1

Viruses, 2022
Borna disease virus 1 (BoDV-1) is a neurotropic RNA virus belonging to the family Bornaviridae within the order Mononegavirales. Whereas BoDV-1 causes neurological and behavioral disorders, called Borna disease (BD), in a wide range of mammals, its ...
Takehiro Kanda, Keizo Tomonaga
doaj   +1 more source

Structure of the RNA-dependent RNA polymerase from COVID-19 virus

Science, 2020
The COVID-19 RNA-synthesizing machine Many in the scientific community have mobilized to understand the virus that is causing the global coronavirus disease 2019 (COVID-19) pandemic. Gao et al.
Yan Gao, Liming Yan, Yucen Huang, Fengjiang Liu, Yao Zhao, Lin Cao, Tao Wang, Qianqian Sun, Z. Ming, Lianqi Zhang, Ji Ge, Litao Zheng, Ying Zhang, Haofeng Wang, Yan Zhu, Chen Zhu, T. Hu, T. Hua, Bing Zhang, Xiuna Yang, Jun Li, Haitao Yang, Zhijie Liu, Wenqing Xu, L. Guddat, Quan Wang, Z. Lou, Z. Rao   +27 more
semanticscholar   +1 more source

Human Papillomavirus Type 16 Circular RNA Is Barely Detectable for the Claimed Biological Activity

mBio, 2022
Human papillomavirus type 16 (HPV16) E7 oncoprotein plays an essential role in cervical carcinogenesis and is encoded predominantly by an E6*I mRNA through alternative RNA splicing of a P97 promoter-transcribed bicistronic E6E7 pre-mRNA.
Lulu Yu, Zhi-Ming Zheng
doaj   +1 more source

In vivo biodistribution analysis of transmission competent and defective RNA virus-based episomal vector

Scientific Reports, 2020
RNA virus-based episomal vector (REVec) is an emerging viral vector system that mediates long-term stable gene expression in variety of cell types in vitro.
Yumiko Komatsu, Chiaki Tanaka, Ryo Komorizono, Keizo Tomonaga   +3 more
doaj   +1 more source

Evolutionary Selection of the Nuclear Localization Signal in the Viral Nucleoprotein Leads to Host Adaptation of the Genus Orthobornavirus

Viruses, 2020
Adaptation of the viral life cycle to host cells is necessary for efficient viral infection and replication. This evolutionary process has contributed to the mechanism for determining the host range of viruses.
Ryo Komorizono, Yukiko Sassa, Masayuki Horie, Akiko Makino, Keizo Tomonaga   +4 more
doaj   +1 more source

Rapid Molecular Detection of SARS-CoV-2 (COVID-19) Virus RNA Using Colorimetric LAMP

medRxiv, 2020
The ability to detect an infectious agent in a widespread epidemic is crucial to the success of quarantine efforts in addition to sensitive and accurate screening of potential cases of infection from patients in a clinical setting.
Yinhua Zhang, Nelson Odiwuor, Jin Xiong, Luo Sun, Raphael Nyaruaba, Hongping Wei, N. Tanner   +6 more
semanticscholar   +1 more source

Dual function of the nuclear export signal of the Borna disease virus nucleoprotein in nuclear export activity and binding to viral phosphoprotein

Virology Journal, 2017
Background Borna disease virus (BoDV), which has a negative-sense, single-stranded RNA genome, causes persistent infection in the cell nucleus. The nuclear export signal (NES) of the viral nucleoprotein (N) consisting of leucine at positions 128 and 131 ...
Mako Yanai, Madoka Sakai, Akiko Makino, Keizo Tomonaga   +3 more
doaj   +1 more source