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Hidden Viral Sequences in Public Sequencing Data and Warning for Future Emerging Diseases
mBio, 2021 RNA viruses cause numerous emerging diseases, mostly due to transmission from mammalian and avian reservoirs. Large-scale surveillance of RNA viral infections in these animals is a fundamental step for controlling viral infectious diseases.
Junna Kawasaki +3 more
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SARS-CoV-2: from its discovery to genome structure, transcription, and replication
Cell & Bioscience, 2021 SARS-CoV-2 is an extremely contagious respiratory virus causing adult atypical pneumonia COVID-19 with severe acute respiratory syndrome (SARS). SARS-CoV-2 has a single-stranded, positive-sense RNA (+RNA) genome of ~ 29.9 kb and exhibits significant ...
Ayslan Castro Brant +4 more
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Reverse Genetics and Artificial Replication Systems of Borna Disease Virus 1
Viruses, 2022 Borna disease virus 1 (BoDV-1) is a neurotropic RNA virus belonging to the family Bornaviridae within the order Mononegavirales. Whereas BoDV-1 causes neurological and behavioral disorders, called Borna disease (BD), in a wide range of mammals, its ...
Takehiro Kanda, Keizo Tomonaga
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Human Papillomavirus Type 16 Circular RNA Is Barely Detectable for the Claimed Biological Activity
mBio, 2022 Human papillomavirus type 16 (HPV16) E7 oncoprotein plays an essential role in cervical carcinogenesis and is encoded predominantly by an E6*I mRNA through alternative RNA splicing of a P97 promoter-transcribed bicistronic E6E7 pre-mRNA.
Lulu Yu, Zhi-Ming Zheng
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Biophysical Modeling of SARS-CoV-2 Assembly: Genome Condensation and Budding [PDF]
Viruses 2022, 14, 2089, 2022 The COVID-19 pandemic caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has spurred unprecedented and concerted worldwide research to curtail and eradicate this pathogen. SARS-CoV-2 has four structural proteins: Envelope (E), Membrane (M), Nucleocapsid (N), and Spike (S), which self-assemble along with its RNA into the ...
arxiv +1 more source
Scientific Reports, 2020 RNA virus-based episomal vector (REVec) is an emerging viral vector system that mediates long-term stable gene expression in variety of cell types in vitro.
Yumiko Komatsu +3 more
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Viruses, 2020 Adaptation of the viral life cycle to host cells is necessary for efficient viral infection and replication. This evolutionary process has contributed to the mechanism for determining the host range of viruses.
Ryo Komorizono +4 more
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One Hour Photo, Seymour Parrish, gnosticism, Demiurge, early Christianity, religious symbolism, cinema, sin, punishment, sword [PDF]
Future Human Image, 2022 This article focuses on the architecture of intersection that exists between emerging infectious diseases, conflict and global governance. Using COVID-19 as both the backdrop for a failed global response as well as a predictive exercise for future ...
Sanjay Pooran
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Polysomally Protected Viruses [PDF]
Phys. Biol. 18 046009 (2021), 2021 It is conceivable that an RNA virus could use a polysome, that is, a string of ribosomes covering the RNA strand, to protect the genetic material from degradation inside a host cell. This paper discusses how such a virus might operate, and how its presence might be detected by ribosome profiling.
arxiv +1 more source
Virology Journal, 2017 Background Borna disease virus (BoDV), which has a negative-sense, single-stranded RNA genome, causes persistent infection in the cell nucleus. The nuclear export signal (NES) of the viral nucleoprotein (N) consisting of leucine at positions 128 and 131 ...
Mako Yanai +3 more
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