Results 21 to 30 of about 719,129 (168)
Hepatitis Delta Virus RNA Replication [PDF]
Viruses, 2009 Hepatitis delta virus (HDV) is a distant relative of plant viroids in the animal world. Similar to plant viroids, HDV replicates its circular RNA genome using a double rolling-circle mechanism. Nevertheless, the production of hepatitis delta antigen (HDAg), which is indispensible for HDV replication, is a unique feature distinct from plant viroids ...
Chung-Hsin Tseng, Michael M. C. Lai
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RNA regulatory processes in RNA virus biology
WIREs RNA, 2019 AbstractNumerous post‐transcriptional RNA processes play a major role in regulating the quantity, quality and diversity of gene expression in the cell. These include RNA processing events such as capping, splicing, polyadenylation and modification, but also aspects such as RNA localization, decay, translation, and non‐coding RNA‐associated regulation ...
Shaun T. Cross +3 more
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Challenges in RNA virus bioinformatics [PDF]
Bioinformatics, 2014 Abstract Motivation: Computer-assisted studies of structure, function and evolution of viruses remains a neglected area of research. The attention of bioinformaticians to this interesting and challenging field is far from commensurate with its medical and biotechnological importance.
Marz Manja +10 more
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HortScience, 2021 MN55 is an apple (Malus ×domestica Borkh.) cultivar recently released by the University of Minnesota apple breeding program, with fruit marketed in the U.S. as Rave®. When stored for 4 months at 0 to 4 °C, MN55 fruit can develop several storage disorders,
Cindy B.S. Tong +6 more
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mBio, 2015 Transcripts of human papillomavirus 16 (HPV16) E6 and E7 oncogenes undergo alternative RNA splicing to produce multiple splice isoforms. However, the importance of these splice isoforms is poorly understood.
Masahiko Ajiro, Zhi-Ming Zheng
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Riboswitching on RNA virus replication [PDF]
Proceedings of the National Academy of Sciences, 2007 Positive-strand RNA viruses direct different virus-specific processes during their infection of host cells. Fundamental events such as viral RNA genome replication are controlled by viral regulatory RNA elements (REs). Here, we have investigated the possibility of specifically modulating the action of a viral RE using RNA aptamer technology.
Sheng, Wang, K Andrew, White
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Lipids and RNA virus replication [PDF]
Current Opinion in Virology, 2014 Most viruses rely heavily on their host machinery to successfully replicate their genome and produce new virus particles. Recently, the interaction of positive-strand RNA viruses with the lipid biosynthetic and transport machinery has been the subject of intense investigation.
Kouacou V, Konan, Lorena, Sanchez-Felipe
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KSHV ORF57, a Protein of Many Faces
Viruses, 2015 Kaposi’s sarcoma-associated herpesvirus (KSHV) ORF57 protein (also known as mRNA transcript accumulation (Mta)) is a potent posttranscriptional regulator essential for the efficient expression of KSHV lytic genes and productive KSHV replication.
Vladimir Majerciak, Zhi-Ming Zheng
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Antagonistic activity against innate immunity determines virulence in mammalian bornaviruses
npj VirusesVariegated squirrel bornavirus 1 (VSBV-1) is a lethal emerging disease that has been discovered in privately owned and zoo squirrels, but its pathogenicity as a zoonotic pathogen remains uncertain.
Akiko Makino +3 more
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Development of an RNA Virus-Based Episomal Vector Capable of Switching Transgene Expression
Frontiers in Microbiology, 2019 Viral vectors are efficient gene delivery systems, although most of these vectors still present limitations to their practical use, such as achieving only transient transgene expression and a risk of insertional mutations.
Yusuke Yamamoto +5 more
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