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The implications of FASN in viral infection and related diseases: a promising target in antiviral therapies. [PDF]
Huang Y +6 more
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Why Andes hantavirus is not the next SARS-CoV-2: contrasting viral shedding, transmissibility and genomic patterns. [PDF]
Bal A +5 more
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Nucleotide sequence analysis reveals the presence of PVY-Tam isolates affecting tamarillo in Colombia. [PDF]
Martínez-Moncayo C +5 more
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Mirusha virus: A novel sand fly-borne phlebovirus with evidence of neutralizing antibodies in humans and dogs in Kosovo. [PDF]
Jakupi X +15 more
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Emerging Roles of tRNAs in RNA Virus Infections
Trends in Biochemical Sciences, 2020Viruses rely on the host cell translation machinery for efficient synthesis of their own proteins. Emerging evidence highlights different roles for host transfer RNAs (tRNAs) in the process of virus replication. For instance, different RNA viruses manipulate host tRNA pools to favor viral protein translation. Interestingly, specific host tRNAs are used
Alexandre Nunes +5 more
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Nature Chemical Biology, 2007
RIG-I is an RNA helicase that senses viral infections and triggers innate and adaptive immune mechanisms. Recent studies have identified RNAs bearing 5′-triphosphates as ligands of RIG-I and have suggested a mechanism for how RIG-I distinguishes viral RNA from host RNA.
Christopher F Basler +1 more
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RIG-I is an RNA helicase that senses viral infections and triggers innate and adaptive immune mechanisms. Recent studies have identified RNAs bearing 5′-triphosphates as ligands of RIG-I and have suggested a mechanism for how RIG-I distinguishes viral RNA from host RNA.
Christopher F Basler +1 more
openaire +1 more source
RNA Silencing in Productive Virus Infections
Annual Review of Phytopathology, 2005RNA silencing can reduce the expression of specific genes through posttranscriptional gene silencing, the microRNA pathway, and also through transcriptional gene silencing. Posttranscriptional gene silencing also acts as an antivirus mechanism. By suppressing this antivirus defense mechanism, viruses affect all three silencing pathways in addition to ...
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