Results 221 to 230 of about 441,359 (251)
Some of the next articles are maybe not open access.
Nature Chemical Biology, 2007
RIG-I is an RNA helicase that senses viral infections and triggers innate and adaptive immune mechanisms. Recent studies have identified RNAs bearing 5′-triphosphates as ligands of RIG-I and have suggested a mechanism for how RIG-I distinguishes viral RNA from host RNA.
Christopher F Basler +1 more
openaire +1 more source
RIG-I is an RNA helicase that senses viral infections and triggers innate and adaptive immune mechanisms. Recent studies have identified RNAs bearing 5′-triphosphates as ligands of RIG-I and have suggested a mechanism for how RIG-I distinguishes viral RNA from host RNA.
Christopher F Basler +1 more
openaire +1 more source
RNA Silencing in Productive Virus Infections
Annual Review of Phytopathology, 2005RNA silencing can reduce the expression of specific genes through posttranscriptional gene silencing, the microRNA pathway, and also through transcriptional gene silencing. Posttranscriptional gene silencing also acts as an antivirus mechanism. By suppressing this antivirus defense mechanism, viruses affect all three silencing pathways in addition to ...
openaire +2 more sources
RVvictor: Virus RNA-directed molecular interactions for RNA virus infection
Computers in Biology and MedicineRNA viruses are major human pathogens that cause seasonal epidemics and occasional pandemic outbreaks. Due to the nature of their RNA genomes, it is anticipated that virus's RNA interacts with host protein (INTPRO), messenger RNA (INTmRNA), and non-coding RNA (INTncRNA) to perform their particular functions during their transcription and replication ...
Kuerbannisha Amahong +7 more
openaire +2 more sources
Infectivity studies of bromegrass mosaic virus RNA
Virology, 1965Abstract The infectivity of bromegrass mosaic virus (BMV) RNA has been investigated. The infectivity per unit weight of unfractionated RNA was approximately one-third that of an equivalent weight of RNA in the virus. No significant loss of infectivity occurred during 70 hours of incubation at 30°.
L E, Bockstahler, P, Kaesberg
openaire +2 more sources
INHIBITION OF CELL FUNCTIONS BY RNA-VIRUS INFECTIONS
Annual Review of Microbiology, 1984The studies with poliovirus have revealed that cells have a full capacity to translate uncapped mRNA, although their own mRNAs are capped and methylated. These observations have been confirmed by translation studies in fractionated systems in vitro.
L, Kääriäinen, M, Ranki
openaire +2 more sources
RNA-RNA Recombination and Evolution in Virus-Infected Plants
Annual Review of Phytopathology, 1994Viruses that depend on RNA-dependent RNA polymerases (RdRp) for repli cation of their genomic and subgenomic RNAs are subject to high inherent misincorporation of nucleotides that can lead to heterogeneous mixtures of related species (46, 93). It has been proposed that RNA viruses evolved the means for correcting high error rates through an ability to
A. E. Simon, J. J. Bujarski
openaire +2 more sources
Immunofluorescent demonstration of double-stranded RNA and virus antigen in RNA virus-infected cells
Virology, 1974Abstract The indirect immunofluorescence procedure has been used for demonstration of double-stranded RNA in cells infected with reovirus, poliomyelitis, and tick-borne encephalitis (TBE) viruses. Rabbit sera against poly(A)-poly(U) and poly(I)-poly(C) react specifically with double-stranded RNA.
I N, Gavrilovskaya +5 more
openaire +2 more sources
Influenza virus, an RNA virus, synthesizes its messenger RNA in the nucleus of infected cells
Cell, 1981Abstract It had not been established whether influenza virus, an RNA virus of negative polarity, synthesizes its mRNA in the nucleus or cytoplasm of infected cells. To determine the site of synthesis, we fractionated infected chicken embryo fibroblasts and BHK-21 cells using both aqueous and nonaqueous procedures, and assayed the pulse-labeled viral ...
C, Herz +3 more
openaire +2 more sources
Virus-specific RNA and DNA in nuclei of cells infected with fowlpox virus
Virology, 1976Abstract Poxviruses appear to be assembled exclusively in the cytoplasm of infected cells, and it has been generally held that all replicative events are restricted to the cytoplasm. Previous work in this laboratory has shown that fowlpox virus (FPV) stimulates DNA synthesis both in vivo and in vitro , which, together with the ability of FPV to ...
L G, Gafford, C C, Randall
openaire +2 more sources
Identification of virus-specific RNA in cells infected with rous sarcoma virus
Biochemical and Biophysical Research Communications, 1971Abstract The cytoplasm and nuclei of cells infected with Rous sarcoma virus contain RNA which can be annealed to single-stranded DNA synthesized by the RNA-dependent polymerase of the virus. Formation of DNA:RNA hybrids was detected by equilibrium centrifugation in Cs 2 SO 4 , and by step-wise elution from hydroxy-apatite.
A C, Garapin +4 more
openaire +2 more sources