The use of attenuated isolates of Pepino mosaic virus for cross-protection [PDF]
, 2010 Pepino mosaic virus (PepMV) has recently emerged as a highly infectious viral pathogen in tomato crops. Greenhouse trials were conducted under conditions similar to commercial tomato production.
Hamelink, R. +5 more
core +2 more sources
Exosomes and Their Role in the Life Cycle and Pathogenesis of RNA Viruses
Viruses, 2015 Exosomes are membrane-enclosed vesicles actively released into the extracellular space, whose content reflect the physiological/pathological state of the cells they originate from.
Harendra Singh Chahar +2 more
doaj +1 more source
Evidence for West Nile Virus and Usutu Virus Infections in Wild and Resident Birds in Germany, 2017 and 2018 [PDF]
, 2019 Wild birds play an important role as reservoir hosts and vectors for zoonotic arboviruses and foster their spread. Usutu virus (USUV) has been circulating endemically in Germany since 2011, while West Nile virus (WNV) was first diagnosed in several bird ...
Eiden, Martin +19 more
core +2 more sources
RNA Viruses: ROS-Mediated Cell Death
International Journal of Cell Biology, 2014 Reactive oxygen species (ROS) are well known for being both beneficial and deleterious. The main thrust of this review is to investigate the role of ROS in ribonucleic acid (RNA) virus pathogenesis.
Mohammad Latif Reshi +2 more
doaj +1 more source
Emerging Microbes and Infections, 2021 Infection by (re-)emerging RNA arboviruses including Chikungunya virus (CHIKV) and Mayaro virus primarily cause acute febrile disease and transient polyarthralgia. However, in a significant subset of infected individuals, debilitating arthralgia persists
Fabian Pott +6 more
doaj +1 more source
Zika virus infection reprograms global transcription of host cells to allow sustained infection. [PDF]
, 2017 Zika virus (ZIKV) is an emerging virus causally linked to neurological disorders, including congenital microcephaly and Guillain-Barré syndrome. There are currently no targeted therapies for ZIKV infection.
Bansal, Vikas +5 more
core +2 more sources
A novel mechanism of RNase L inhibition: Theiler\u27s virus L* protein prevents 2-5A from binding to RNase L [PDF]
, 2018 The OAS/RNase L pathway is one of the best-characterized effector pathways of the IFN antiviral response. It inhibits the replication of many viruses and ultimately promotes apoptosis of infected cells, contributing to the control of virus spread ...
Drappier, Melissa +8 more
core +8 more sources
Computer-designed orthogonal RNA aptamers programmed to recognize Ebola virus glycoproteins
Biosafety and Health, 2019 Ebola virus (EBOV), a member of the filovirus family, is an enveloped negative-sense RNA virus that causes lethal infections in humans and primates.
Yue Teng +6 more
doaj +1 more source
Biochemical prevention and treatment of viral infections – A new paradigm in medicine for infectious diseases [PDF]
, 2004 For two centuries, vaccination has been the dominating approach to develop prophylaxis against viral infections through immunological prevention. However, vaccines are not always possible to make, are ineffective for many viral infections, and also carry
Fang, Fang, Le Calvez, Hervé, Yu, Mang
core +3 more sources
Nora virus persistent infections are not affected by the RNAi machinery. [PDF]
PLoS ONE, 2009 Drosophila melanogaster is widely used to decipher the innate immune system in response to various pathogens. The innate immune response towards persistent virus infections is among the least studied in this model system. We recently discovered a picorna-
Mazen S Habayeb +2 more
doaj +1 more source