Results 41 to 50 of about 447,697 (355)
Emerging Microbes and Infections, 2021 Infection by (re-)emerging RNA arboviruses including Chikungunya virus (CHIKV) and Mayaro virus primarily cause acute febrile disease and transient polyarthralgia. However, in a significant subset of infected individuals, debilitating arthralgia persists
Fabian Pott +6 more
doaj +1 more source
Zika virus infection reprograms global transcription of host cells to allow sustained infection. [PDF]
, 2017 Zika virus (ZIKV) is an emerging virus causally linked to neurological disorders, including congenital microcephaly and Guillain-Barré syndrome. There are currently no targeted therapies for ZIKV infection.
Bansal, Vikas +5 more
core +2 more sources
Self-organized critical dynamics of RNA virus evolution [PDF]
arXiv, 2022 RNA virus (e.g., SARS-CoV-2) evolves in a complex manner. Studying RNA virus evolution is vital for understanding molecular evolution and medicine development. Scientists lack, however, general frameworks to characterize the dynamics of RNA virus evolution directly from empirical data and identify potential physical laws. To fill this gap, we present a
arxiv
Effect of the charge distribution of virus coat proteins on the length of packaged RNAs [PDF]
, 2020 Single-stranded RNA viruses efficiently encapsulate their genome into a protein shell called the capsid. Electrostatic interactions between the positive charges in the capsid protein's N-terminal tail and the negatively charged genome have been postulated as the main driving force for virus assembly.
arxiv +1 more source
Viral Genome Segmentation Can Result from a Trade-Off between Genetic Content and Particle Stability [PDF]
, 2011 The evolutionary benefit of viral genome segmentation is a classical, yet unsolved question in evolutionary biology and RNA genetics. Theoretical studies anticipated that replication of shorter RNA segments could provide a replicative advantage over ...
Arias, Armando +7 more
core +3 more sources
Quantifying the relative contribution of free virus and cell-to-cell transmission routes to the propagation of hepatitis C virus infections in vitro using an agent-based model [PDF]
arXiv, 2021 Experiments have shown that hepatitis C virus (HCV) infections in vitro disseminate both distally via the release and diffusion of cell-free virus through the medium, and locally via direct, cell-to-cell transmission. To determine the relative contribution of each mode of infection to HCV dissemination, we developed an agent-based model (ABM) that ...
arxiv
Functional RNA during Zika virus infection
Virus Research, 2018 Zika virus (ZIKV; family Flaviviridae; genus Flavivirus) is a pathogenic mosquito-borne RNA virus that currently threatens human health in the Americas, large parts of Asia and occasionally elsewhere in the world. ZIKV infection is often asymptomatic but can cause severe symptoms including congenital microcephaly and Guillain-Barré syndrome.
Gorben P. Pijlman +4 more
openaire +4 more sources
RNA Viruses: ROS-Mediated Cell Death
International Journal of Cell Biology, 2014 Reactive oxygen species (ROS) are well known for being both beneficial and deleterious. The main thrust of this review is to investigate the role of ROS in ribonucleic acid (RNA) virus pathogenesis.
Mohammad Latif Reshi +2 more
doaj +1 more source
Possible roles of endogenous RNA virus elements in RNA virus infection
Uirusu, 2016 While ebola virus disease (EVD) outbreak in West Africa seemed to be subsided, there are still some sporadic cases reported from the field. Many studies were conducted during the outbreak. It was identified that the virus can survive for a long period in certain areas of the survivors and they can be a reservoir.
Tomoyuki Honda, Keizo Tomonaga
openaire +7 more sources
Nora virus persistent infections are not affected by the RNAi machinery. [PDF]
PLoS ONE, 2009 Drosophila melanogaster is widely used to decipher the innate immune system in response to various pathogens. The innate immune response towards persistent virus infections is among the least studied in this model system. We recently discovered a picorna-
Mazen S Habayeb +2 more
doaj +1 more source