Results 51 to 60 of about 605,647 (350)
Background: The main threat to human health is infectious disease. For the treatment of infections with RNA viruses, there are hardly any antiviral drugs in the market.
Gajala Deethamvali Ghouse Peer +4 more
doaj +1 more source
Mycoviruses as Triggers and Targets of RNA Silencing in White Mold Fungus Sclerotinia sclerotiorum
This study aimed to demonstrate the existence of antiviral RNA silencing mechanisms in Sclerotinia sclerotiorum by infecting wild-type and RNA-silencing-deficient strains of the fungus with an RNA virus and a DNA virus.
Pauline Mochama +3 more
doaj +1 more source
The unceasing circulation of SARS-CoV-2 leads to the continuous emergence of novel viral sublineages. Here, we isolate and characterize XBB.1, XBB.1.5, XBB.1.9.1, XBB.1.16.1, EG.5.1.1, EG.5.1.3, XBF, BA.2.86.1 and JN.1 variants, representing >80% of ...
Delphine Planas +24 more
doaj +1 more source
Viral diseases have been a major limiting factor threating sustainable potato (Solanum tuberosum L.) production in Pakistan. Surveys were conducted to serologically quantify the incidence of RNA viruses infecting potato; Potato virus X (PVX), Potato ...
Amir Hameed +3 more
doaj +1 more source
Dengue virus type 2 infections of Aedes aegypti are modulated by the mosquito's RNA interference pathway. [PDF]
A number of studies have shown that both innate and adaptive immune defense mechanisms greatly influence the course of human dengue virus (DENV) infections, but little is known about the innate immune response of the mosquito vector Aedes aegypti to ...
Irma Sánchez-Vargas +7 more
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Prevalence of dengue, chikungunya and zika viruses in blood donors in Kunming, China
Objective To investigate the prevalence of zika virus (ZIKV), dengue virus (DENV) and chikungunya virus (CHIKV) infections in blood donors in Kunming, China.
ZHANG Zhihui +7 more
doaj +1 more source
Zika Virus Infection and Prolonged Viremia in Whole-Blood Specimens
We tested whole-blood and plasma samples from immunocompetent patients who had had benign Zika virus infections and found that Zika virus RNA persisted in whole blood substantially longer than in plasma.
Jean Michel Mansuy +6 more
doaj +1 more source
In vivo evidence for quasispecies distributions in the bovine respiratory syncytial virus genome [PDF]
We analyzed the genetic evolution of bovine respiratory syncytial virus (BRSV) isolate W2-00131, from its isolation in bovine turbinate (BT) cells to its inoculation in calves.
Bonnet, Marion +5 more
core +1 more source
Equine arteritis virus-infected cells contain six polyadenylated virus-specific RNAs
The kinetics of equine arteritis virus growth and virus-specific RNA synthesis at 40° were determined in BHK-21 cells. Maximum titers of infectious virus (∼10(7) PFU/ml) were observed at 12 hr p.i., while incorporation of [(3)H]uridine into virus-specific RNA became detectable at 4 hr p.i. and increased to reach a maximum rate at 8 hr p.i. This RNA was
Horzinek, M.C. +2 more
openaire +3 more sources

