Sequestration of G3BP coupled with efficient translation inhibits stress granules in Semliki Forest virus infection [PDF]
, 2012 Dynamic, mRNA-containing stress granules (SGs) form in the cytoplasm of cells under environmental stresses, including viral infection. Many viruses appear to employ mechanisms to disrupt the formation of SGs on their mRNAs, suggesting that they represent
Eng, Kai Er +6 more
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Mathematical model of plant-virus interactions mediated by RNA interference [PDF]
J. Theor. Biol. 403, 129-142 (2016), 2016 Cross-protection, which refers to a process whereby artificially inoculating a plant with a mild strain provides protection against a more aggressive isolate of the virus, is known to be an effective tool of disease control in plants. In this paper we derive and analyse a new mathematical model of the interactions between two competing viruses with ...
arxiv +1 more source
Biochemical prevention and treatment of viral infections – A new paradigm in medicine for infectious diseases [PDF]
, 2004 For two centuries, vaccination has been the dominating approach to develop prophylaxis against viral infections through immunological prevention. However, vaccines are not always possible to make, are ineffective for many viral infections, and also carry
Fang, Fang, Le Calvez, Hervé, Yu, Mang
core +3 more sources
Mycoviruses as Triggers and Targets of RNA Silencing in White Mold Fungus Sclerotinia sclerotiorum
Viruses, 2018 This study aimed to demonstrate the existence of antiviral RNA silencing mechanisms in Sclerotinia sclerotiorum by infecting wild-type and RNA-silencing-deficient strains of the fungus with an RNA virus and a DNA virus.
Pauline Mochama +3 more
doaj +1 more source
Dengue virus type 2 infections of Aedes aegypti are modulated by the mosquito's RNA interference pathway. [PDF]
PLoS Pathogens, 2009 A number of studies have shown that both innate and adaptive immune defense mechanisms greatly influence the course of human dengue virus (DENV) infections, but little is known about the innate immune response of the mosquito vector Aedes aegypti to ...
Irma Sánchez-Vargas +7 more
doaj +1 more source
Inhibition of type I interferon induction and signalling by mosquito-borne flaviviruses [PDF]
, 2017 The Flavivirus genus (Flaviviridae family) contains a number of important human pathogens, including dengue and Zika viruses, which have the potential to cause severe disease.
Clark, Jordan J. +3 more
core +1 more source
Role of HIV RNA structure in recombination and speciation: romping in purine A, keeps HTLV away [PDF]
Microbes and Infection (2014) 16, 96-103, 2013 Extreme enrichment of the human immunodeficiency virus (HIV-1) RNA genome for the purine A parallels the mild purine-loading of the RNAs of most organisms. This should militate against loop-loop "kissing" interactions between the structured viral genome and structured host RNAs, which can generate segments of double-stranded RNA sufficient to trigger ...
arxiv +1 more source
Widespread recombination, reassortment, and transmission of unbalanced compound viral genotypes in natural arenavirus infections. [PDF]
, 2015 Arenaviruses are one of the largest families of human hemorrhagic fever viruses and are known to infect both mammals and snakes. Arenaviruses package a large (L) and small (S) genome segment in their virions.
Chang, Li-Wen +13 more
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Phosphorylation of TGB1 by protein kinase CK2 promotes barley stripe mosaic virus movement in monocots and dicots. [PDF]
, 2015 The barley stripe mosaic virus (BSMV) triple gene block 1 (TGB1) protein is required for virus cell-to-cell movement. However, little information is available about how these activities are regulated by post-translational modifications. In this study, we
Han, Chenggui +11 more
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The Plant Pathology Journal, 2014 Viral diseases have been a major limiting factor threating sustainable potato (Solanum tuberosum L.) production in Pakistan. Surveys were conducted to serologically quantify the incidence of RNA viruses infecting potato; Potato virus X (PVX), Potato ...
Amir Hameed +3 more
doaj +1 more source