Results 101 to 110 of about 3,202,245 (403)

Construction of Stable Reporter Flaviviruses and Their Applications

Viruses, 2020
Flaviviruses are significant human pathogens that cause frequent emerging and reemerging epidemics around the world. Better molecular tools for studying, diagnosing, and treating these diseases are needed.
Coleman Baker, Pei-Yong Shi
doaj   +1 more source

Radial distribution of RNA genome packaged inside spherical viruses

, 2008
The problem of RNA genomes packaged inside spherical viruses is studied. The viral capsid is modeled as a hollowed sphere. The attraction between RNA molecules and the inner viral capsid is assumed to be non-specific and occurs at the inner capsid ...
J. Johnson, P.-G. de Gennes, Se Il Lee, Toan T. Nguyen   +3 more
core   +1 more source

Positive-sense RNA viruses reveal the complexity and dynamics of the cellular and viral epitranscriptomes during infection

Nucleic Acids Research, 2018
More than 140 post-transcriptional modifications (PTMs) are known to decorate cellular RNAs, but their incidence, identity and significance in viral RNA are still largely unknown.
W. McIntyre, Rachel Netzband, G. Bonenfant, Jason M. Biegel, Clare M. Miller, G. Fuchs, E. Henderson, Manoj Arra, M. Canki, D. Fabris, Cara T. Pager   +10 more
semanticscholar   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Contribution of hypoxia inducible factor-1 during viral infections

Virulence, 2020
Hypoxia-inducible factor 1 (HIF-1) is a transcription factor that plays critical roles during the cellular response to hypoxia. Under normoxic conditions, its function is tightly regulated by the degradation of its alpha subunit (HIF-1α), which impairs ...
Antonia Reyes, Nicolás Corrales, Nicolás M. S. Gálvez, Susan M. Bueno, Alexis M. Kalergis, Pablo A. González   +5 more
doaj   +1 more source

Bionanomaterials from plant viruses [PDF]

, 2015
Plant virus capsids have emerged as useful biotemplates for material synthesis. All plant virus capsids are assembled with high-precision, three-dimensional structures providing nanoscale architectures that are highly monodisperse, can be produced in ...
Aljabali, Alaa A. A., Evans, David
core   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Multicolor Stimulated Emission Depletion (STED) Microscopy to Generate High-resolution Images of Respiratory Syncytial Virus Particles and Infected Cells

Bio-Protocol, 2017
Human respiratory syncytial virus (RSV) infection in human lung epithelial A549 cells induces filopodia, cellular protrusions consisting of F-actin, that extend to neighboring uninfected cells (Mehedi et al., 2016). High-resolution imaging via stimulated
Masfique Mehedi, Margery Smelkinson, Juraj Kabat, Sundar Ganesan, Peter Collins, Ursula Buchholz   +5 more
doaj   +1 more source

Emerging and Re-emerging Viral Infections in the 21st Century: Microbiological and Public Health Perspectives [PDF]

Journal of Krishna Institute of Medical Sciences University, 2021
Pathogens, especially viruses and bacteria are known to have great potential to emerge and evolve for thousands of years and it seems to be a never-ending process.
Mohan Bilikallahalli Sannathimmappa, Vinod Nambiar, Rajesh Patil   +2 more
doaj  

Molecular studies on a complex of potyviruses infecting solanaceous crops, and some specific virus-host interactions [PDF]

, 2003
This thesis constitutes a comprehensive analysis of the molecular and biological characteristics of three potyviruses (genus Potyvirus, family Potyviridae) naturally occurring in cultivated and wild species of family Solanaceae: Peru tomato virus (PTV ...
Spetz, Carl
core