Results 251 to 260 of about 3,202,245 (403)

High-Resolution Metatranscriptomics Reveals the Ecological Dynamics of Mosquito-Associated RNA Viruses in Western Australia

Journal of Virology, 2017
M. Shi, P. Neville, J. Nicholson, John-Sebastian Eden, A. Imrie, E. Holmes   +5 more
semanticscholar   +1 more source

Potent Liver‐Tropic mRNA Lipid Nanoparticles: ApoE‐Mediated Delivery Through a Low‐Density Lipoprotein Receptor Independent Uptake Mechanism

Advanced Materials, EarlyView.
Helper and ionizable lipids play a crucial role in determining ApoE binding and subsequent liver tropism and LDLR‐mediated uptake. Ionizable lipids primarily govern the LDLR‐independent uptake pathway. This complementary interplay between lipid components ultimately governs LNP delivery performance and therapeutic efficacy in the liver.
Ashish Sarode, Christian Ortiz, Tadeh Derstepanian, Natalia Vargas‐Montoya, Priyal Patel, Nikita Khadse, Saikat Manna, Ryan Landis, Joseph Skaleski, Lianne Boeglin, Hongfeng Deng, Anusha Dias, Hong Wang, Debora Barreiros Petropolis, Barak Yahalom, Shrirang Karve, Frank DeRosa   +16 more
wiley   +1 more source

Metagenomic Detection of RNA Viruses of <i>Hyalomma asiaticum</i> Ticks in the Southern Regions of Kazakhstan. [PDF]

Microorganisms
Sultankulova KT, Kozhabergenov NS, Shynybekova GO, Chervyakova OV, Usserbayev BS, Alibekova DA, Zhunushov AT, Orynbayev MB.   +7 more
europepmc   +1 more source

Serotonergic System‐Targeted Nucleic Acid Hydrogel Coordinates Excitability Restoration and Circuit Reconstruction for Spinal Cord Injury Therapy

Advanced Materials, EarlyView.
The study reports a DNA/RNA heteroduplex hydrogel (SeroPTEN‐CG) that undergoes DNase‐mediated hydrogel‐to‐nanogel transition for spinal cord injury therapy by targeting the serotonergic system, combining 5‐hydroxytryptamine (5‐HT)‐mediated excitability restoration to reactivate dormant interneurons with phosphatase and tensin homolog (PTEN)‐targeted ...
Chunlin Li, Xiaoqing Zhao, Kai Jiang, Haixia Kang, Shuo Liu, Linlin Jiang, Baoshuai Bai, Haonan Cui, Ziyang Zhang, Menglei Dong, Ruizhi Zhang, Chenbo Zou, Shenghui Shang, Chi Zhang, Xiangchuang Fan, Lijuan Zhu, Huiquan Duan, Chuan Zhang, Shiqing Feng, Hengxing Zhou   +19 more
wiley   +1 more source

Five novel RNA viruses of the invasive big-headed ant (Pheidole megacephala). [PDF]

Arch Virol
Hartle CT, Lee CC, Hsu HW, Lin CY, Liu KL, Chang JY, Lawrence JA, Tay JW, Yang CS.   +8 more
europepmc   +1 more source

Increasing hepatitis C virus RNA levels in hemophiliacs: relationship to human immunodeficiency virus infection and liver disease. Multicenter Hemophilia Cohort Study [PDF]

, 1994
M. Elaine Eyster, MW Fried, AM Di Bisceglie, J. J. Goedert   +3 more
openalex   +1 more source

Label‐Free Sensing of Coronaviral Sequences via Kretschmann‐Configuration Reflectance Spectroscopic Ellipsometry: Sensitivity, Specificity, and Interfacial Effects

Advanced Materials Interfaces, EarlyView.
Spectroscopic ellipsometry in the Kretschmann‐Raether configuration (KRSE) is employed to characterize a DNA‐functionalized platform for viral sequence recognition. By merging SE with surface plasmon resonance, KRSE outperforms conventional SE, achieving nanomolar targeting through resonance wavelength shifts (δλ) measurements. Its enhanced interfacial
Silvia Maria Cristina Rotondi, Paolo Canepa, Francesco Bisio, Ornella Cavalleri, Maurizio Canepa   +4 more
wiley   +1 more source

Codon Usage Bias in Human RNA Viruses and Its Impact on Viral Translation, Fitness, and Evolution. [PDF]

Viruses
Ventoso I.
europepmc   +1 more source

Bioinformatic and Physical Characterizations of Genome-Scale Ordered RNA Structure in Mammalian RNA Viruses

, 2008
Matthew P. Davis, Selena M. Sagan, John Paul Pezacki, David J. Evans, Peter Simmonds   +4 more
openalex   +2 more sources

Hepatitis C Virus RNA Elimination and Development of Resistance in Replicon Cells Treated with BMS-790052 [PDF]

, 2012
Chunfu Wang, Haichang Huang, Lourdes Valera, Jin-Hua Sun, Donald R. O’Boyle, Peter T. Nower, Lingling Jia, Dike Qiu, Xin Huang, Aneela Altaf, Min Gao, Robert A. Fridell   +11 more
openalex   +1 more source