Results 21 to 30 of about 369,072 (266)

Comparative Profiling of Ubiquitin Proteasome System Interplay with Influenza A Virus PB2 Polymerase Protein Recapitulating Virus Evolution in Humans

open access: yesmSphere, 2017
The optimized exploitation of cell resources is one cornerstone of a successful infection. Differential mapping of host-pathogen protein-protein interactions (PPIs) on the basis of comparative interactomics of multiple strains is an effective strategy to
Elise Biquand   +14 more
doaj   +1 more source

PicPreview and PicSummary: Two Timesaving Plugins for the Fluorescence Microscopist

open access: yesCells, 2021
This article targets cell biologists who use fluorescence microscopy but lack automatic tools to summarize and manage their image datasets. When using microscopy to document a phenotype, multiple and random pictures are required to reflect the biological
Gabrielle Vieyres
doaj   +1 more source

RNA chaperones encoded by RNA viruses [PDF]

open access: yesVirologica Sinica, 2015
RNAs are functionally diverse macromolecules whose proper functions rely strictly upon their correct tertiary structures. However, because of their high structural flexibility, correct folding of RNAs is challenging and slow. Therefore, cells and viruses encode a variety of RNA remodeling proteins, including helicases and RNA chaperones. In RNA viruses,
Yang, Jie   +3 more
openaire   +2 more sources

Development of an RNA Virus-Based Episomal Vector Capable of Switching Transgene Expression

open access: yesFrontiers in Microbiology, 2019
Viral vectors are efficient gene delivery systems, although most of these vectors still present limitations to their practical use, such as achieving only transient transgene expression and a risk of insertional mutations.
Yusuke Yamamoto   +5 more
doaj   +1 more source

A novel SARS-CoV-2 related coronavirus in bats from Cambodia

open access: yesNature Communications, 2021
In this study, Delaune et al., isolate and characterise a SARS-CoV-2-related coronavirus from two bats sampled in Cambodia. Their findings suggest that the geographic distribution of SARS-CoV-2-related viruses is wider than previously reported.
Deborah Delaune   +17 more
doaj   +1 more source

Early phylodynamics analysis of the COVID-19 epidemic in France

open access: yesPeer Community Journal, 2021
France was one of the first countries to be reached by the COVID-19 pandemic. Here, we analyse 196 SARS-Cov-2 genomes collected between Jan 24 and Mar 24 2020, and perform a phylodynamics analysis.
Danesh, Gonché   +17 more
doaj   +1 more source

Translation of Plant RNA Viruses [PDF]

open access: yesViruses, 2021
Plant RNA viruses encode essential viral proteins that depend on the host translation machinery for their expression. However, genomic RNAs of most plant RNA viruses lack the classical characteristics of eukaryotic cellular mRNAs, such as mono-cistron, 5′ cap structure, and 3′ polyadenylation.
Guowei Geng   +7 more
openaire   +3 more sources

RNA viruses and mutations

open access: yesUirusu, 2005
Actively replicating RNA viruses in nature are continually changing their genetic information by spontaneous mutations. These changes often result in alterations in immune-sensitivity, drug-sensitivity, cell-tropism, and host-range, causing uncontrollability of the pathogen and emerging/re-emerging infections. To better understand the virus changes and
Hironori, Sato, Masaru, Yokoyama
openaire   +3 more sources

Tudor-SN Promotes Early Replication of Dengue Virus in the Aedes aegypti Midgut

open access: yesiScience, 2020
Summary: Diseases caused by mosquito-borne viruses have been on the rise for the last decades, and novel methods aiming to use laboratory-engineered mosquitoes that are incapable of carrying viruses have been developed to reduce pathogen transmission ...
Sarah Hélène Merkling   +9 more
doaj   +1 more source

Virus-derived DNA drives mosquito vector tolerance to arboviral infection

open access: yesNature Communications, 2016
Mosquitoes tolerate long-lasting viral infections, which makes them efficient vectors for human viral diseases. Here, the authors show that the tolerance of Aedesmosquitoes to infection with dengue or chikungunya viruses depends on the production of ...
Bertsy Goic   +10 more
doaj   +1 more source

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