Results 221 to 230 of about 778,146 (302)

Short peptide perturbs spermatogenesis via immune microenvironment dysregulation and mitochondrial imbalance

FEBS Open Bio, EarlyView.
In the blood–testis barrier, occludin is crucial for tight junctions. This study demonstrates that occludin‐targeting short peptides disrupt junction integrity, inducing immune cell infiltration, tumor necrosis factor‐α/interleukin‐6 secretion and mitochondrial dysfunction, ultimately triggering apoptosis.
Heng Wang, Xiaofang Tan, Deyu Chen
wiley   +1 more source

Architecture of an RNA polymerase ribozyme illuminates the RNA World. [PDF]

Trends Genet
Shechner DM.
europepmc   +1 more source

Seq'ing identity and function in a repeat-derived noncoding RNA world. [PDF]

Chromosome Res, 2020
O'Neill RJ.
europepmc   +1 more source

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

FEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian, Khodakaram Jahanbin, Shekoofeh Nikooei, Marzieh Rostaminejad, Arezoo Rahimi, Pedram Abdizadeh, Behnam Alipoor   +6 more
wiley   +1 more source

Origin of the RNA World in Cold Hadean Geothermal Fields Enriched in Zinc and Potassium: Abiogenesis as a Positive Fallout from the Moon-Forming Impact? [PDF]

Life (Basel)
Mulkidjanian AY, Dibrova DV, Bychkov AY.
europepmc   +1 more source

Multi-agent approach to sequence structure simulation in the RNA World hypothesis. [PDF]

PLoS One, 2020
Synak J, Rybarczyk A, Blazewicz J.
europepmc   +1 more source

Gene expression associated with PTSD in World Trade Center responders: An RNA sequencing study [PDF]

, 2017
Pei Fen Kuan, Monika A. Waszczuk, Roman Kotov, Sean Clouston, Xiaohua Yang, Prashant K. Singh, Sean T. Glenn, Eduardo Cortes Gomez, Jianmin Wang, Evelyn J. Bromet, Benjamin J. Luft   +10 more
openalex   +1 more source

An efficient strategy for producing RNA‐free Nucleocapsid protein of SARS‐CoV‐2 for biochemical and structural investigations

FEBS Open Bio, EarlyView.
Cleavable N‐terminal Thioredoxin fusion enabled soluble expression and purification of otherwise insoluble SARS‐CoV‐2 Nucleocapsid (N) protein. A four‐step purification strategy yielded highly homogeneous, RNA‐free N protein. Binding assays showed high RNA affinity (Kd ~ 28 nm). The study will facilitate high‐resolution structural studies of N protein,
Shweta Singh, Gagan D. Gupta
wiley   +1 more source

Constraint on an RNA world on montmorillonite clay. [PDF]

Biophys J
Mizuuchi R.
europepmc   +1 more source

Post-transcriptional Processing of mRNA in Neurons: The Vestiges of the RNA World Drive Transcriptome Diversity [PDF]

, 2018
Catia Andreassi, Hamish Crerar, Antonella Riccio   +2 more
openalex   +1 more source