Results 221 to 230 of about 836,536 (329)

Origin of the RNA World in Cold Hadean Geothermal Fields Enriched in Zinc and Potassium: Abiogenesis as a Positive Fallout from the Moon-Forming Impact? [PDF]

Life (Basel)
Mulkidjanian AY, Dibrova DV, Bychkov AY.
europepmc   +1 more source

Boron and the RNA world

, 2019
Roberto Laos, Steven Benner
openalex   +1 more source

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

FEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito, Masashi Arakawa, Koki Maeda, Eiji Morita   +3 more
wiley   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Origin & influence of autocatalytic reaction networks at the advent of the RNA world. [PDF]

RNA Biol
Zorc SA, Roy RN.
europepmc   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

From Mutation Signature to Molecular Mechanism in the RNA World: A Case of SARS-CoV-2. [PDF]

Genomics Proteomics Bioinformatics, 2020
Yu J.
europepmc   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

The RNA world: from experimental laboratory to "in silico" approach. Part 1: User friendly RNA expression databases portals. [PDF]

Rep Pract Oncol Radiother
Kolenda T, Śmiełowska M, Lipowicz J, Ostapowicz J, Pacześna P, Rosochowicz MA, Poter P, Kozłowska-Masłoń J, Guglas K, Dudek K, Grzejda N, Regulska K, Florczak A, Kazimierczak U, Lamperska K, Teresiak A.   +15 more
europepmc   +1 more source

Circular RNAs from linear viral RNA genomes: A distinct dimension in the virus world

Eugene V. Koonin
openalex   +1 more source