Results 231 to 240 of about 778,146 (302)

Matrix: a complex amalgam of structures and functions in tumor microenvironment

FEBS Open Bio, EarlyView.
The matrix is a dynamic, intricate three‐dimensional mesh of biomolecules with both structural and functional properties. This review deals with the complexity of this ‘molecular amalgam’ in the tumor microenvironment and highlights its importance in the maintenance and evolution of tumors by describing certain matrix biomolecules, such as ...
Spyros S. Skandalis, Evgenia Tsoukala, Theodora D. Sarantopoulou, Maria‐Elpida Christopoulou   +3 more
wiley   +1 more source

Characterization of ribosome heterogeneity during endothelial to hematopoietic transition

FEBS Open Bio, EarlyView.
The panorama of ribosome heterogeneity during embryonic hematopoiesis has not yet been portrayed. In this study, utilizing dual‐omics data, the heterogenous dynamic of ribosome during endothelial‐to‐hematopoietic transition has been systemically described. Moreover, stage‐specific upregulation and peripheral localization of RPL27 and RACK1 in hemogenic
Xitong Tian, Di Liu, Bing Liu, Yu Lan, Jie Zhou   +4 more
wiley   +1 more source

Circular at the very beginning: on the initial genomes in the RNA world. [PDF]

RNA Biol
Luo Y, Liang M, Yu C, Ma W.
europepmc   +1 more source

Liver‐specific lncRNAs associated with liver cancers

FEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) are regulatory molecules with various functions. They are more tissue‐specific than proteins and can be used as potential biomarkers, particularly in cancer diagnostics and prognosis. In this review, we have systematically compiled all lncRNAs with exclusive expression in the human liver, verified their liver specificity ...
Olga Y. Burenina, Roman K. Makarchenko, Maria P. Rubtsova, Olga A. Dontsova   +3 more
wiley   +1 more source

Origin & influence of autocatalytic reaction networks at the advent of the RNA world. [PDF]

RNA Biol
Zorc SA, Roy RN.
europepmc   +1 more source

Characterization of WAC interactions with R2TP and TTT chaperone complexes linking glucose and glutamine availability to mTORC1 activity

FEBS Open Bio, EarlyView.
TTT and R2TP chaperone complexes are required for the assembly and activation of mTORC1. WAC directly interacts with components of TTT, R2TP, and mTORC1, and these interactions are affected by the availability of glucose and glutamine, correlating with changes in mTORC1 activity.
Sofía Cabezudo, Natalia Cuervo, Carmen García‐Martín, Andrés López‐Perrote, Clara Reglero, Adrián Maqueda‐Real, Ana González‐Corpas, Marina Serna, Diego Megías, Alejo Efeyan, Solip Park, Oscar Llorca   +11 more
wiley   +1 more source

The RNA world: from experimental laboratory to "in silico" approach. Part 1: User friendly RNA expression databases portals. [PDF]

Rep Pract Oncol Radiother
Kolenda T, Śmiełowska M, Lipowicz J, Ostapowicz J, Pacześna P, Rosochowicz MA, Poter P, Kozłowska-Masłoń J, Guglas K, Dudek K, Grzejda N, Regulska K, Florczak A, Kazimierczak U, Lamperska K, Teresiak A.   +15 more
europepmc   +1 more source

From Mutation Signature to Molecular Mechanism in the RNA World: A Case of SARS-CoV-2. [PDF]

Genomics Proteomics Bioinformatics, 2020
Yu J.
europepmc   +1 more source

A vast world of viroid-like circular RNAs revealed by mining metatranscriptomes

, 2022
Benjamin D. Lee, Uri Neri, Simon Roux, Yuri I. Wolf, Antônio Pedro Camargo, Mart Krupovìč, Peter Simmonds, Nikos C. Kyrpides, Uri Gophna, Valeria V. Dolja, Eugene V. Koonin   +10 more
openalex   +2 more sources

Polydatin ameliorates ovalbumin‐induced asthma in a rat model through NCOA4‐mediated ferroautophagy and ferroptosis pathway

FEBS Open Bio, EarlyView.
In this research, a rat model of asthma was created using OVA, and polydatin served as an intervention. By inhibiting ferroautophagy mediated by NCOA4 and averting ferroptosis, polydatin has been demonstrated to reduce asthma. This work presents new ideas for investigating the mechanism of polydatin's ability to alleviate asthma, in addition to ...
Wei Li, Yuwei Tang, Wenkang Liu, Fang Fang, Jiepeng Wang, Chaoyi Fang   +5 more
wiley   +1 more source