Results 41 to 50 of about 7,640,682 (253)
Solvation and Stabilization of Single Strand RNA at the Air/ice Interface Support a Primordial RNA World on Ice [PDF]
, 2020 Outstanding questions about the RNA world hypothesis for the emergence of lifeon Earth concern the stability and self-replication of prebiotic aqueous RNA.Recent experimental work has suggested that solid substrates and lowtemperatures could help resolve
Margaret, Berrens +4 more
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Traversing the RNA world [PDF]
Journal of Biological Chemistry, 2017 An invitation to write a "Reflections" type of article creates a certain ambivalence: it is a great honor, but it also infers the end of your professional career. Before you vanish for good, your colleagues look forward to an interesting but entertaining account of the ups-and-downs of your past research and your views on science in general, peppered ...
openaire +3 more sources
Complete probabilistic analysis of RNA shapes [PDF]
, 2006 Voß B, Giegerich R, Rehmsmeier M. Complete probabilistic analysis of RNA shapes. BMC Biology. 2006;4(1): 5.Background: Soon after the first algorithms for RNA folding became available, it was recognised that the prediction of only one energetically ...
Marc Rehmsmeier +8 more
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Reviving the RNA world: An insight into the appearance of RNA methyltransferases
Frontiers in Genetics, 2016 RNA, the earliest genetic and catalytic molecule, has a relatively delicate and labile chemical structure, when compared to DNA. It is prone to be damaged by alkali, heat, nucleases or stress conditions. One mechanism to protect RNA or DNA from damage is
Ajay Kumar Rana, Serge eAnkri
doaj +1 more source
Diverging affinity of tospovirus RNA silencing suppressor proteins, NSs, for various RNA duplex molecules [PDF]
, 2010 The tospovirus NSs protein was previously shown to suppress the antiviral RNA silencing mechanism in plants. Here the biochemical analysis of NSs proteins from different tospoviruses, using purified NSs or NSs containing cell extracts, is described.
Kormelink, R.J.M. +16 more
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RNA Synthesis by in Vitro Selected Ribozymes for Recreating an RNA World
Life, 2015 The RNA world hypothesis states that during an early stage of life, RNA molecules functioned as genome and as the only genome-encoded catalyst. This hypothesis is supported by several lines of evidence, one of which is the in vitro selection of catalytic
Lyssa L. Martin +2 more
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Formamide significantly enhances the efficiency of chemical adenylation of RNA sequencing ligation adaptors [PDF]
, 2023 Preadenylated single-stranded DNA ligation adaptors are essential reagents in many next generation RNA sequencing library preparation protocols. These oligonucleotides can be adenylated enzymatically or chemically.
Watts, Jonathan K +4 more
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Riboswitches and the RNA World [PDF]
Cold Spring Harbor Perspectives in Biology, 2010 Riboswitches are structured noncoding RNA domains that selectively bind metabolites and control gene expression (Mandal and Breaker 2004a; Coppins et al. 2007; Roth and Breaker 2009). Nearly all examples of the known riboswitches reside in noncoding regions of messenger RNAs where they control transcription or translation.
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FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
The secret life of RNA and lipids
RNA BiologyThere is no life without RNA or lipids. But could there be life with only RNA and lipids? The discovery that RNA can catalyse reactions in addition to encoding information opened new directions for engineering life and the possibility of life emerging ...
Tomasz Czerniak, James P Saenz
doaj +1 more source