Results 31 to 40 of about 837,608 (280)
Methanol in the RNA world: An astrochemical perspective
Frontiers in Astronomy and Space Sciences, 2022 The role and relevance of methanol in the origin and structure of the RNA world is discussed. Methanol is a pivotal, renewable, and regenerable source from which almost all chemical materials, simple or complex, can be accessed.
Thomas Mathew +2 more
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Two genetic codes: Repetitive syntax for active non-coding RNAs; non-repetitive syntax for the DNA archives [PDF]
, 2017 Current knowledge of the RNA world indicates 2 different genetic codes being present throughout the living world. In contrast to non-coding RNAs that are built of repetitive nucleotide syntax, the sequences that serve as templates for proteins share—as ...
Guenther, Witzany
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The new world of RNA diagnostics and therapeutics
Journal of Experimental & Clinical Cancer Research, 2023 The 5th Workshop IRE on Translational Oncology was held in Rome (Italy) on 27–28 March at the IRCCS Regina Elena National Cancer Institute. This meeting entitled “The New World of RNA diagnostics and therapeutics” highlightes the significant progress in ...
Giovanni Blandino +18 more
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The RNA Worlds in Context [PDF]
Cold Spring Harbor Perspectives in Biology, 2011 There are two RNA worlds. The first is the primordial RNA world, a hypothetical era when RNA served as both information and function, both genotype and phenotype. The second RNA world is that of today's biological systems, where RNA plays active roles in catalyzing biochemical reactions, in translating mRNA into proteins, in regulating gene expression,
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Acta Societatis Botanicorum Poloniae, 2014 Among the numerous hypotheses offering a scenario for the origin of life on Earth, the one called “The RNA World” has gained the most attention. According to this hypothesis RNA acted as a genetic information storage material, as a catalyst of all ...
Zofia Szweykowska-Kulińska
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Impact of template backbone heterogeneity on RNA polymerase II transcription. [PDF]
, 2014 Variations in the sugar component (ribose or deoxyribose) and the nature of the phosphodiester linkage (3'-5' or 2'-5' orientation) have been a challenge for genetic information transfer from the very beginning of evolution.
Chong, Jenny +5 more
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Reflections on the RNA world [PDF]
RNA, 2015 The authors of these reflections are a generation apart, yet their career paths have much in common. After training in medicine, they both followed the call of “real science” to discover a passion for the world of RNAs, a little corner of which they are now exploring jointly. This is a brief account of these meanderings.
Zavolan, Mihaela, Keller, Walter
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RNA Vaccine: novel approach for cancer treatment [PDF]
, 2011 Cancer is still an unsolved puzzle and a major cause of mortality and morbidity in the world. Today, about one in every thousand people is dying due to cancer. No effective agent has yet been found which can cure cancer in its metastatic stage.
Kanika Bhalla +2 more
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The RNA World: 4,000,000,050 years old
Life, 2015 The RNA World is now some four billion years behind us, but only recently turned 50 as a human hypothesis. [...]
Niles Lehman
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RNA, 2015 My research entered the RNA world when I joined the EMBL Heidelberg. During my doctoral and postdoctoral research I had focused on developing and applying solution NMR methods and studied protein structure and dynamics of the Bcl family proteins, which are important regulators of apoptosis.
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