Results 11 to 20 of about 837,608 (280)

RNA world [PDF]

, 2011
Nisu pronađeni nikakvi dokazi o postojanju precelularnog života. Svi zaključci o njegovom postojanju su pretpostavke. Iako je teško zamisliti nastanak života iz neživog, precelularni život se morao pojaviti u vrlo kratkom vremenu.
Čule, Ana-Marija
core   +5 more sources

The Impact of Mutant p53 in the Non-Coding RNA World [PDF]

Biomolecules, 2020
Long non-coding RNAs (lncRNAs), circular RNAs (circRNAs), micro RNAs (miRNAs), and extracellular RNAs (exRNAs) are new groups of RNAs with regulation activities that have low or no protein-coding ability.
Silvia Di Agostino
doaj   +2 more sources

How Amino Acids and Peptides Shaped the RNA World

Life, 2015
The “RNA world” hypothesis is seen as one of the main contenders for a viable theory on the origin of life. Relatively small RNAs have catalytic power, RNA is everywhere in present-day life, the ribosome is seen as a ribozyme, and rRNA and tRNA are ...
Peter T.S. van der Gulik, Dave Speijer
doaj   +3 more sources

A novel viroid-like RNA element “Obelisks”: a major breakthrough in the RNA World [PDF]

Molecular Biomedicine
Li Li, Xinqin Zhang, Min Wu
doaj   +2 more sources

Editorial: The non-coding RNA world in animals and plants [PDF]

Frontiers in Genetics
Lingling Wang, Bin Hu, Min-Jin Han, Min-Jin Han, Q.-Z. Zhou   +4 more
doaj   +2 more sources

RNA silencing sheds light on the RNA world. [PDF]

PLoS Biology, 2006
RNA silencing — also known as RNA interference — is an intriguing phenomenon in which short, double-stranded RNA “triggers” can prevent the expression of specific genes. First discovered in plants, RNA interference is now recognized as a widespread, if not ubiquitous, phenomenon, and it is causing great excitement as an experimental technique for ...
Rachel Jones
doaj   +4 more sources

Safari in the RNA world: a special issue focused on RNA biogenesis, functions, and technologies [PDF]

Acta Biochimica et Biophysica Sinica
Chang Ya-Nan, Cheng Hong
doaj   +2 more sources

Chaperna: linking the ancient RNA and protein worlds

RNA Biology, 2021
As a mental framework for the transition of self-replicating biological forms, the RNA world concept stipulates a dual function of RNAs as genetic substance and catalyst.
Ahyun Son, Scott Horowitz, Baik L. Seong
doaj   +1 more source

Drugging the RNA World. [PDF]

Cold Spring Harb Perspect Biol, 2018
Although we live in the remnants of an RNA world, the world of drug discovery and chemical probes is firmly protein-centric. Developing highly selective small molecules targeting RNA is often considered to be an insurmountable challenge. Our goal is to demystify the design of such compounds.
Disney MD, Dwyer BG, Childs-Disney JL.
europepmc   +4 more sources

A Polyaddition Model for the Prebiotic Polymerization of RNA and RNA-Like Polymers

Life, 2020
Implicit in the RNA world hypothesis is that prebiotic RNA synthesis, despite occurring in an environment without biochemical catalysts, produced the long RNA polymers which are essential to the formation of life.
Alex Spaeth, Mason Hargrave
doaj   +1 more source