Results 121 to 130 of about 198,612 (296)

Identification, Expression and Function of Heat Shock Transcription Factor (HSF-1) Gene in Exopalaemon carinicauda Under High Temperature Stress [PDF]

open access: yesProgress in Fishery Sciences
Exopalaemon carinicauda, a shrimp Litopenaeus vannamei species endemic to China, holds significant economic value due to its desirable meat quality, high protein content, and low fat levels, making it a popular choice among consumers.
XIA Jinqi   +7 more
doaj   +1 more source

Heat Stress Promotes Fibroblast‐Derived WNT5A Secretion Through m6A Modification to Activate Melanogenesis

open access: yesAdvanced Science, EarlyView.
Heat stress promotes WNT5A secretion from fibroblasts via METTL3/YTHDC1‐dependent m6A methylation. Subsequently, WNT5A binds to FZD10 on melanocytes, activating β‐catenin‐driven melanogenesis. ABSTRACT As the impact of global warming continues to intensify, the effects of heat stress on the skin are becoming increasingly evident.
Yuanyuan Wan   +13 more
wiley   +1 more source

Identification and functional analysis of six DNAJ genes from Myzus persicae (Hemiptera: Aphididae) in response to UV-B stress

open access: yesEuropean Journal of Entomology
Ultraviolet B (UV-B) is a significant environmental factor affecting insect development, survival, and reproduction. DNAJ proteins are molecular chaperones found ubiquitously in insects that are crucial for their adaptation to environmental stresses ...
Long-Chun HE   +5 more
doaj   +1 more source

Entwicklung und Etablierung von induzierbaren RNAi-Systemen zur Regulierung der Expression von Polo-like Kinase 1 (Plk1) in vitro und in vivo [PDF]

open access: yes, 2007
RNA-Interferenz (RNAi) erlangte eine herausragende Bedeutung zum Studium der Genfunktion, nachdem auch in Säugersystemen gezeigt wurde, daß durch Applikation von 21 nt langen siRNAs (small interfering RNAs) eine Sequenz-spezifische Degradierung der mRNA ...
Kappel, Sven
core  

Adaptation of Echinococcus Multilocularis to Oxidative Stress Depends on EmPDK‐Mediated Metabolic Reprogramming

open access: yesAdvanced Science, EarlyView.
Metabolic adaption presents a vital survival strategy for E. multilocularis. This study identifies EmPDK as a central metabolic regulator governing glucose metabolic reprogramming. Oxidative stress activates EmHIF1α to induce EmPDK expression. Mechanistic characterization reveals this ROS/EmHIF1α/EmPDK axis drives glycolytic reprogramming to sustain ...
Huijuan Wang   +5 more
wiley   +1 more source

Functional analysis of two SfHsp90 genes in response to high temperature and insecticide stress in Spodoptera frugiperda (Lepidoptera: Noctuidae)

open access: yesEuropean Journal of Entomology
Spodoptera frugiperda, a worldwide pest, can feed on 353 crops species, including corn, rice, and sorghum. It is highly adaptable to various environments.
Hong-Yun RUAN   +4 more
doaj   +1 more source

Suppression of WWP1 Gene Via RNAi Induced the Reduction of Proliferation Rate of C2C12 Myoblasts

open access: yesThe Journal of Poultry Science, 2010
The WW domain containing E3 ubiquitin protein ligase 1 (WWP1), which plays an important role in ubiquitin-proteasome pathway to degrade unneeded or damaged proteins, was recently identified as the responsible for chicken muscular dystrophy.
Hirokazu Matsumoto   +5 more
doaj   +1 more source

Sildenafil feeding suppresses w-RNAi-induced delay of locomotor recovery.

open access: yes, 2017
(A) Time to recovery in flies (w+;; R50E11-Gal4/UAS-w-RNAi) fed with food containing 0, 1, 10 or 100 μM sildenafil. * P μM sildenafil). Flies were fed for 4 days after eclosion. * P μM sildenafil. Feeding duration was the same as B.
Chengfeng Xiao (192558)   +1 more
core   +1 more source

Concerted Action of Targeted Nucleic Acid Therapeutics as Flexible, Precision and Personalized Cancer Treatment

open access: yesAdvanced Science, EarlyView.
Combinations of small activating RNAs and small interfering RNAs were developed as personalized precision therapies that simultaneously activate tumor suppressors and silence oncogenes according to the molecular signatures of patient tumors. This combination strategy demonstrated superior anticancer efficacy, highlighting the promise of precision ...
Jing Wu   +18 more
wiley   +1 more source

RNAi-mediated depletion of Rcd1, Rcd5 or MBD-R2 reduces the levels of Cid and Ndc80.

open access: yes, 2019
(A) Western blotting analysis and band intensity quantification relative to the control from 3 independent experiments showing that in Rcd1, Rcd5, MBD-R2 and wds RNAi cells the Cid level is reduced to 38%, 43%, 42% and 78% of the control level ...
Anastasiya L. Oshchepkova (7392689)   +11 more
core   +1 more source

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