Results 221 to 230 of about 195,676 (344)

Tall, skinny, RNAi decaf, to go [PDF]

, 2003
Tudor Toma
openalex   +1 more source

A virus-targeted plant receptor-like kinase promotes cell-to-cell spread of RNAi

Proceedings of the National Academy of Sciences of the United States of America, 2018
Tábata Rosas-Díaz, Dan Zhang, Pengfei Fan, Liping Wang, Xue Ding, Yuli Jiang, Tamara Jimenez-Gongora, L. Medina-Puche, Xinyan Zhao, Zhengyan Feng, Guiping Zhang, Xiaokun Liu, E. Bejarano, Li Tan, Heng Zhang, Jian‐Kang Zhu, Weiman Xing, C. Faulkner, Shingo Nagawa, Rosa Lozano-Durán   +19 more
semanticscholar   +1 more source

Helping RNAi Deliver

Molecular Therapy, 2005
openaire   +3 more sources

Zic family member 5 promotes RIO kinase 3 expression to enhance pancreatic cancer survival

The FEBS Journal, EarlyView.
This study demonstrates that targeting ZIC5 increases gemcitabine sensitivity and induces pancreatic cancer shrinkage in vivo. The findings also show that ALDH3B1, PTGES, and TUFT1, the downstream genes of ZIC5, contribute to gemcitabine resistance in pancreatic cancer cells.
Reiko Satow, Yuki Kashiwaba, Misaki Okao, Shin Takano, Yuna Aiga, Atsuko Yoneda, Kazuyoshi Hosomichi, Kiyoko Fukami   +7 more
wiley   +1 more source

The Drosophila histone variant H2Av facilitates Notch signaling activity in a two-tier regulatory fashion. [PDF]

Cell Commun Signal
Chen Y, Zhang X, Song Y, Shen J, Zhang J.   +4 more
europepmc   +1 more source

A guide to heat shock factors as multifunctional transcriptional regulators

The FEBS Journal, EarlyView.
The heat shock factors (HSFs) are evolutionarily conserved transcription factors best known as regulators of molecular chaperone genes in response to heat shock and other protein‐damaging stresses. Vertebrate HSFs, HSF1‐5, HSFX, and HSFY, are implicated in various physiological and pathological processes, including organismal development and cancer ...
Hendrik S. E. Hästbacka, Alejandro J. Da Silva, Lea Sistonen, Eva Henriksson   +3 more
wiley   +1 more source

Divide and survive: PuZFP1 coordinates dual root developmental pathways for drought adaptation in Populus. [PDF]

Plant Physiol
Torres-Martínez HH.
europepmc   +1 more source

Reaping the rewards of RNAi [PDF]

, 2003
Jonathan B Weitzman
openalex   +1 more source

Targeting of Antithrombin in Hemophilia A or B with RNAi Therapy

New England Journal of Medicine, 2017
K. Pasi, S. Rangarajan, P. Georgiev, T. Mant, T. Mant, M. D. Creagh, T. Lissitchkov, D. Bevan, S. Austin, C. Hay, I. Hegemann, R. Kazmi, P. Chowdary, L. Gercheva‐Kyuchukova, V. Mamonov, M. Timofeeva, C. Soh, P. Garg, A. Vaishnaw, Akin Akinc, B. Sørensen, M. Ragni   +21 more
semanticscholar   +1 more source

High‐throughput screening identifies a previously undescribed checkpoint controlling mitotic progression in response to DNA damage

The FEBS Journal, EarlyView.
DNA damage can cause mitotic delay to allow DNA repair to occur. However, the mechanism underlying this is unclear. Here, we show that in response to cells entering mitosis with DNA damage, SOD1 restrains PP2a activity via oxidation of cysteine residues at the active site. This leads to a reduction in PP2a activity at the mitotic kinetochore, resulting
Nan Li, Rachel Gatenby, Thomas Walne, Caroline Daye, Steven Watson, Priya Lata, Stephen Brown, Ruth Thompson   +7 more
wiley   +1 more source