Results 281 to 290 of about 330,568 (380)

The efficacy of longevity interventions in Caenorhabditis elegans is determined by the early life activity of RNA splicing factors. [PDF]

PLoS Biol
Dutta S, Perez Matos MC, Heintz C, Mutlu AS, Piper M, Mistry M, Sharma A, Morrow CS, Smith H, Howell P, Sehgal R, Lanjuin A, Wang MC, Mair WB.   +13 more
europepmc   +1 more source

Helping RNAi Deliver

Molecular Therapy, 2005
openaire   +2 more sources

Screening of a multi-virus resistant RNAi construct in cowpea through transient vacuum infiltration method

, 2019
K. Prasad Babu, M. Manamohan, R. Asokan, M. Krishna Reddy   +3 more
openalex   +2 more sources

RNF13 is a previously undescribed interactor of iduronate 2‐sulfatase that modifies its glycosylation and maturation

The FEBS Journal, EarlyView.
Iduronate 2‐sulfatase (IDS; purple) is expressed as a precursor protein that goes through multiple steps of maturation, modification, and trafficking to become an active lysosomal enzyme that degrades glycosaminoglycans. Our study shows that the transmembrane ubiquitin ligases RNF13 (orange) and RNF167 (pink) heterodimerize, affecting IDS intracellular
Valérie C. Cabana, Antoine Y. Bouchard, Audrey M. Sénécal, Laurent Cappadocia, Marc P. Lussier   +4 more
wiley   +1 more source

Knockdown of PR-DUB subunit calypso in the developing Drosophila eye and wing results in mis-patterned tissues with altered size and shape. [PDF]

G3 (Bethesda)
Luf M, Begani P, Bowcock AM, Pfleger CM.
europepmc   +1 more source

Lentivirus-delivered stable gene silencing by RNAi in primary cells.

RNA: A publication of the RNA Society, 2003
S. Stewart, Derek M. Dykxhoorn, D. Palliser, H. Mizuno, E. Yu, D. An, D. Sabatini, I. Chen, W. Hahn, P. Sharp, R. Weinberg, C. Novina   +11 more
semanticscholar   +1 more source

LAT1/SLC7A5‐mediated amino acid uptake is regulated by redox signals triggered by formyl‐peptide receptor 2

The FEBS Journal, EarlyView.
FPR2 activation mediates NOX‐dependent LAT1 expression and, in turn, promotes mTORC1 signaling. Upon stimulation with WKYMVm, the FPR2‐NOX2‐ROS axis upregulates LAT1 via increased c‐Myc phosphorylation and decreased miR‐126. Additionally, it promotes CD98 translocation to the plasma membrane.
Myrhiam Cassese, Chiara Brignola, Stefano Marrone, Gabriella Esposito, Rosario Ammendola, Fabio Cattaneo   +5 more
wiley   +1 more source

Nanomaterial-Mediated RNAi Targeting Chitin Metabolism Genes in MEAM1 Cryptic Species of <i>Bemisia tabaci</i> (Hemiptera: Aleyrodidae). [PDF]

Insects
Kong D, Gu H, Gao Y, Hou Y, Li J.
europepmc   +1 more source

Intrinsic specificity of a ‘core’ TIP60 acetyltransferase complex in Drosophila

The FEBS Journal, EarlyView.
The intrinsic substrate selectivity of the Drosophila TIP60‐core acetyltransferase was determined using synthetic nucleosome arrays. Targeted mass spectrometry revealed site‐specific acetylation of histones H2A, H2A.V, and H4, uncovering distinct acetylation rates and patterns across individual lysines.
Silke Krause, Marco Borsò, Marisa Müller, Axel Imhof, Zivkos Apostolou, Peter B. Becker   +5 more
wiley   +1 more source

The conserved outer mitochondrial membrane protein Mtch regulates mitophagy during Drosophila intestinal development. [PDF]

PLoS Biol
Restrepo LJ, Graslie JK, Fortier TM, Baehrecke EH.   +3 more
europepmc   +1 more source