Results 41 to 50 of about 330,568 (380)

Effects of silencing APN gene on proliferation, invasion and apoptosis of human glioma U251 cells

Di-san junyi daxue xuebao, 2020
Objective To determine the effect of aminopeptidase N (APN) on the proliferation, invasion, and apoptosis in human glioma U251 cells and to investigate the possible mechanism.
DONG Yunpeng, CHENG Yuan, CHEN Jin
doaj   +1 more source

Improving RNAi efficiency for pest control in crop species

BioTechniques, 2020
The application of RNAi promotes the development of novel approaches toward plant protection in a sustainable way. Genetically modified crops expressing dsRNA have been developed as commercial products with great potential in insect pest management ...
Shuo Yan, Binyuan Ren, Bo Zeng, Jie Shen
semanticscholar   +1 more source

The Roles of DNA Methyltransferases 1 (DNMT1) in Regulating Sexual Dimorphism in the Cotton Mealybug, Phenacoccus solenopsis

Insects, 2020
The cotton mealybug, Phenacoccus solenopsis, is an invasive pest that can cause massive damage to many host plants of agricultural importance. P. solenopsis is highly polyphagous, and shows extreme sexual dimorphism between males and females.
Mohamed A.A. Omar, Meizhen Li, Feiling Liu, Kang He, Muhammad Qasim, Huamei Xiao, Mingxing Jiang, Fei Li   +7 more
doaj   +1 more source

The ribosomal protein RACK1 is required for microRNA function in both C. elegans and humans [PDF]

, 2011
Despite the importance of microRNAs (miRNAs) in gene regulation, it is unclear how the miRNA-Argonaute complex-or miRNA-induced silencing complex (miRISC)-can regulate the translation of their targets in such diverse ways.
Bajan, Sarah, Banville, Isabelle H., Bouasker, Samir, Giguère, Nellie J., Hutvagner, Gyorgy, Jannot, Guillaume, Piquet, Sandra, Simard, Martin J.   +7 more
core   +3 more sources

Silencing of STAT3 via Peptidomimetic LNP-Mediated Systemic Delivery of RNAi Downregulates PD-L1 and Inhibits Melanoma Growth

Biomolecules, 2020
Cutaneous melanoma is the most aggressive skin cancer with notorious drug resistance. Inhibition of immune checkpoint molecules is one of the most promising approaches for cancer therapy.
Ehexige Ehexige, Mingming Bao, Purevbat Bazarjav, Xiang Yu, Hai Xiao, Shuqin Han, Huricha Baigude   +6 more
doaj   +1 more source

Tracking autophagy during proliferation and differentiation of trypanosoma brucei [PDF]

, 2014
Autophagy is a lysosome-dependent degradation mechanism that sequesters target cargo into autophagosomal vesicles. The Trypanosoma brucei genome contains apparent orthologues of several autophagy-related proteins including an ATG8 family. These ubiquitin-
Coombs, Graham H., Jones, Nathaniel G., Mottram, Jeremy C., Proto, William R.   +3 more
core   +3 more sources

dsRNA Uptake in Plant Pests and Pathogens: Insights into RNAi-Based Insect and Fungal Control Technology

Plants, 2020
Efforts to develop more environmentally friendly alternatives to traditional broad-spectrum pesticides in agriculture have recently turned to RNA interference (RNAi) technology.
Nick Wytinck, Christopher L Manchur, Vivian Li, S. Whyard, Mark F. Belmonte   +4 more
semanticscholar   +1 more source

Limitations in harnessing oral RNA interference as an antiviral strategy in Aedes aegypti

iScience
Summary: Mosquitoes, particularly Aedes aegypti, are critical vectors for globally significant pathogenic viruses. This study examines the limitations of oral RNA interference (RNAi) as a strategy to disrupt viral transmission by Ae. aegypti.
Ottavia Romoli, Annabelle Henrion-Lacritick, Hervé Blanc, Lionel Frangeul, Maria-Carla Saleh   +4 more
doaj   +1 more source

Functional interplay between ribosomal protein paralogues in the eRpL22 family in Drosophila melanogaster

Fly, 2018
Duplicated ribosomal protein (RP) genes in the Drosophila melanogaster eRpL22 family encode structurally-divergent and differentially-expressed rRNA-binding RPs.
Catherine M. Mageeney, Michael G. Kearse, Brett W. Gershman, Caroline E. Pritchard, Jennifer M. Colquhoun, Vassie C. Ware   +5 more
doaj   +1 more source

Genome-wide Identification and Bioinformatics Analysis of Scavenger Receptor Gene Family in Plutella xylostella

Guangdong nongye kexue, 2023
【Objective】The resistance of Plutella xylostella to chemical insecticides is increasing year by year, which makes RNAi (RNA interference) pesticides widely concerned. The P.
Jianbin TAN, Jin XU, Peiqiong SHI, Hongkai ZHOU   +3 more
doaj   +1 more source