Results 71 to 80 of about 323,847 (388)
Targeted mutagenesis of the Sap47 gene of Drosophila: Flies lacking the synapse associated protein of 47 kDa are viable and fertile [PDF]
, 2004 BACKGROUND: Conserved proteins preferentially expressed in synaptic terminals of the nervous system are likely to play a significant role in brain function.
Becker, Sonja +4 more
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Molecular Cell, 2003 RNA interference (RNAi) describes the ability of double-stranded RNA (dsRNA) to inhibit homologous gene expression at the RNA or DNA level. In a recent paper, Feinberg and Hunter report that a single transmembrane dsRNA transport protein may enable RNAi to spread systemically from one cell to another.
openaire +3 more sources
Cellular phenotyping by RNAi [PDF]
Briefings in Functional Genomics and Proteomics, 2006 A systematic characterization of genes with unknown function is a key challenge after the sequencing of the human genome and the genomes of many model organisms. High-throughput RNA-interference (RNAi) screenings have become a widely used approach in invertebrate model organisms and also promise to revolutionize cell biology in mammals.
Michael Boutros, Florian Fuchs
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Exit from Pluripotency Assay of Mouse Embryonic Stem Cells
Bio-Protocol, 2017 A novel method to assess the dissolution of the core pluripotency transcription-factor circuit of mouse Embryonic Stem Cells (mESCs) has been developed (Ying et al., 2003; Betschinger et al., 2013).
Daniel Cirera-Salinas, Constance Ciaudo
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Molecules, 2020 Development of nanotechnology has become prominent in many fields, such as medicine, electronics, production of materials, and modern drugs. Nanomaterials and nanoparticles have gained recognition owing to the unique biochemical and physical properties ...
Anna Graczyk +3 more
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Effector Caspase Dcp-1 and IAP Protein Bruce Regulate Starvation-Induced Autophagy during Drosophila Melanogaster Oogenesis [PDF]
, 2008 A complex relationship exists between autophagy and apoptosis, but the regulatory mechanisms underlying their interactions are largely unknown. We conducted a systematic study of Drosophila melanogaster cell death–related genes to determine their ...
Barbosa, Sharon González +4 more
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Nature Methods, 2011 A recent study turns the creation of conditional short hairpin RNA transgenic mice into a rapid, flexible and scalable process.
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RNAi and Heterochromatin Assembly [PDF]
Cold Spring Harbor Perspectives in Biology, 2015 The involvement of RNA interference (RNAi) in heterochromatin formation has become clear largely through studies in the fission yeast Schizosaccharomyces pombe and plants like Arabidopsis thaliana. This article discusses how heterochromatic small interfering RNAs are produced and how the RNAi machinery participates in the formation and function of ...
Danesh Moazed, Robert A. Martienssen
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BMC Plant BiologyBackground Mungbean is one of the most economically important grain legume crops in Asia. Functional genomics studies in mungbean are necessary to understand the molecular mechanisms behind agronomic traits, to advance the crop improvement. However, this
Sanjeev Kumar +3 more
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When an Intruder Comes Home: GM and GE Strategies to Combat Virus Infection in Plants
AgricultureViruses are silent enemies that intrude and take control of the plant cell’s machinery for their own multiplication. Infection by viruses and the resulting damage is still a major challenge in the agriculture sector.
Adeeb Rahman, Neeti Sanan-Mishra
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