Results 201 to 210 of about 1,710,125 (310)

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Editorial: The role of circular RNAs and MicroRNAs in non-small cell lung cancer: from mechanisms to therapeutic potential. [PDF]

Front Oncol
Tirpe A, Campomenosi P, Berindan-Neagoe I.   +2 more
europepmc   +1 more source

Circular RNAs in the Mammalian Brain Are Highly Abundant, Conserved, and Dynamically Expressed.

Molecules and Cells, 2015
A. Rybak-Wolf, Christin Stottmeister, Petar Glažar, Marvin Jens, Natalia S Pino, S. Giusti, M. Hanan, Mikaela Behm, Osnat Bartok, Reut Ashwal-Fluss, Margareta Herzog, Luisa Schreyer, Panagiotis Papavasileiou, Andranik Ivanov, Marie Öhman, D. Refojo, Sebastian Kadener, N. Rajewsky   +17 more
semanticscholar   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

The complete mitochondrial genome of <i>Brevimulticaecum sinensis</i> (Nematoda: Heterocheilidae), the first representative of the genus <i>Brevimulticaecum</i>. [PDF]

Mitochondrial DNA B Resour
Zhao J, Marisa T, Tu G, Kuris A, Wu X.
europepmc   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

The noncoding RNA revolution—three decades and still going strong!

Molecular Oncology, 2019
George A. Calin
doaj   +1 more source

Stress-induced breakup: tRNA-derived small RNAs in biology. [PDF]

Trends Cell Biol
Li G, Hao T, Ivanov P, Das S.
europepmc   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Correction: Roles of exosomal non-coding RNAs in osteoarthritis. [PDF]

Front Immunol
Lu J, Wen J, Ji J.
europepmc   +1 more source